| Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8. | Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8.
Mizote Y, Inoue T, Akazawa T, Kunimasa K, Tamiya M, Kumamoto Y, Tsuda A, Yoshida S, Tatsumi K, Ekawa T, Honma K, Nishino K, Tahara H., Free PMC Article | 04/24/2024 |
| MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination. | MFG-E8 Alleviates Cognitive Impairments Induced by Chronic Cerebral Hypoperfusion by Phagocytosing Myelin Debris and Promoting Remyelination.
Dong X, Zhang Z, Shu X, Zhuang Z, Liu P, Liu R, Xia S, Bao X, Xu Y, Chen Y., Free PMC Article | 04/16/2024 |
| PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the beta5 integrin. | PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
Datta R, Mukherjee D, Podolsky MJ, Yang CD, Alba DL, Singh S, Arnold TD, Koliwad S, Lizama CO, Atabai K., Free PMC Article | 02/27/2024 |
| MFG-E8 facilitates heart repair through M1/M2 polarization after myocardial infarction by inhibiting CaMKII. | MFG-E8 facilitates heart repair through M1/M2 polarization after myocardial infarction by inhibiting CaMKII.
Ding P, Liu J, Meng Y, Wang H, Huang Y, Su G, Xia C, Du X, Dong N, Cui T, Zhang J, Li J. | 01/4/2024 |
| hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B. | hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B.
Ma J, Li Y, Chen M, Wang W, Zhao Q, He B, Zhang M, Jiang Y. | 06/9/2023 |
| Medin co-aggregates with vascular amyloid-beta in Alzheimer's disease. | Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.
Wagner J, Degenhardt K, Veit M, Louros N, Konstantoulea K, Skodras A, Wild K, Liu P, Obermüller U, Bansal V, Dalmia A, Häsler LM, Lambert M, De Vleeschouwer M, Davies HA, Madine J, Kronenberg-Versteeg D, Feederle R, Del Turco D, Nilsson KPR, Lashley T, Deller T, Gearing M, Walker LC, Heutink P, Rousseau F, Schymkowitz J, Jucker M, Neher JJ., Free PMC Article | 12/17/2022 |
| MFG-E8 has guiding significance for the prognosis and treatment of sepsis. | MFG-E8 has guiding significance for the prognosis and treatment of sepsis.
Wu W, Wang J, Chen J, Lu J, Lao Y, Huang K, Lin J., Free PMC Article | 12/17/2022 |
| MicroRNA-34b-5p binds enhancer of zeste 2 to inhibit milk fat globule-EGF factor 8 expression, affecting liver fibrosis. | MicroRNA-34b-5p binds enhancer of zeste 2 to inhibit milk fat globule-EGF factor 8 expression, affecting liver fibrosis.
Ma J, Liu Q, Chen M, He B, Li Y, Zhang M, Jiang Y. | 12/3/2022 |
| MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-kappaB Signaling in Mice. | MFG-E8 Knockout Aggravated Nonalcoholic Steatohepatitis by Promoting the Activation of TLR4/NF-κB Signaling in Mice.
Hu J, Du H, Yuan Y, Guo P, Yang J, Yin X, Liu J, Wu S, Wan J, Gong X., Free PMC Article | 07/9/2022 |
| MFG-E8 Reduces Aortic Intimal Proliferation in a Murine Model of Transplant Vasculopathy. | MFG-E8 Reduces Aortic Intimal Proliferation in a Murine Model of Transplant Vasculopathy.
Brilland B, Laplante P, Thebault P, Geoffroy K, Brissette MJ, Latour M, Chassé M, Qi S, Hébert MJ, Cardinal H, Cailhier JF., Free PMC Article | 04/30/2022 |
| Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation. | Increased MFG-E8 at neuromuscular junctions is an exacerbating factor for sarcopenia-associated denervation.
Ikemoto-Uezumi M, Zhou H, Kurosawa T, Yoshimoto Y, Toyoda M, Kanazawa N, Nakazawa T, Morita M, Tsuchida K, Uezumi A., Free PMC Article | 04/2/2022 |
| Protective Effect of MFG-E8 on Necroptosis-Induced Intestinal Inflammation and Enteroendocrine Cell Function in Diabetes. | Protective Effect of MFG-E8 on Necroptosis-Induced Intestinal Inflammation and Enteroendocrine Cell Function in Diabetes.
Hua X, Li B, Yu F, Zhao W, Tan Y, Li X, Fu C, Yu X, Gao H, Cheng M., Free PMC Article | 03/19/2022 |
| MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy. | MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy.
Marazuela P, Solé M, Bonaterra-Pastra A, Pizarro J, Camacho J, Martínez-Sáez E, Kuiperij HB, Verbeek MM, de Kort AM, Schreuder FHBM, Klijn CJM, Castillo-Ribelles L, Pancorbo O, Rodríguez-Luna D, Pujadas F, Delgado P, Hernández-Guillamon M., Free PMC Article | 01/29/2022 |
| Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart. | Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart.
Patil M, Saheera S, Dubey PK, Kahn-Krell A, Kumar Govindappa P, Singh S, Tousif S, Zhang Q, Lal H, Zhang J, Qin G, Krishnamurthy P., Free PMC Article | 01/15/2022 |
| Milk fat globule EGF factor 8 restores mitochondrial function via integrin-medicated activation of the FAK-STAT3 signaling pathway in acute pancreatitis. | Milk fat globule EGF factor 8 restores mitochondrial function via integrin-medicated activation of the FAK-STAT3 signaling pathway in acute pancreatitis.
Ren Y, Liu W, Zhang L, Zhang J, Bi J, Wang T, Wang M, Du Z, Wang Y, Zhang L, Wu Z, Lv Y, Meng L, Wu R., Free PMC Article | 12/25/2021 |
| Autoregulation of insulin receptor signaling through MFGE8 and the alphavbeta5 integrin. | Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin.
Datta R, Lizama CO, Soltani AK, Mckleroy W, Podolsky MJ, Yang CD, Huynh TL, Cautivo KM, Wang B, Koliwad SK, Abumrad NA, Atabai K., Free PMC Article | 12/4/2021 |
| MFG-E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose-Dependent Mediation of Actin Polymerization. | MFG-E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose-Dependent Mediation of Actin Polymerization.
Chiang HY, Chu PH, Chen SC, Lee TH., Free PMC Article | 10/30/2021 |
| MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice. | MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice.
Bu HF, Subramanian S, Geng H, Wang X, Liu F, Chou PM, Du C, De Plaen IG, Tan XD., Free PMC Article | 10/23/2021 |
| MRP8/14 mediates macrophage efferocytosis through RAGE and Gas6/MFG-E8, and induces polarization via TLR4-dependent pathway. | MRP8/14 mediates macrophage efferocytosis through RAGE and Gas6/MFG-E8, and induces polarization via TLR4-dependent pathway.
Li K, Chen G, Luo H, Li J, Liu A, Yang C, Wang J, Xu J, Gao S, Chen P, Jiang Y. | 09/11/2021 |
| Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8. | Propofol suppresses microglial phagocytosis through the downregulation of MFG-E8.
Cai X, Li Y, Zheng X, Hu R, Li Y, Xiao L, Wang Z., Free PMC Article | 09/11/2021 |
| MFG-E8 alleviates oxygen-glucose deprivation-induced neuronal cell apoptosis by STAT3 regulating the selective polarization of microglia. | MFG-E8 alleviates oxygen-glucose deprivation-induced neuronal cell apoptosis by STAT3 regulating the selective polarization of microglia.
Fang YY, Zhang JH. | 08/28/2021 |
| Milk Fat Globule-Epidermal Growth Factor-Factor 8 Improves Hepatic Steatosis and Inflammation. | Milk Fat Globule-Epidermal Growth Factor-Factor 8 Improves Hepatic Steatosis and Inflammation.
Zhang L, Tian R, Yao X, Zhang XJ, Zhang P, Huang Y, She ZG, Li H, Ji YX, Cai J. | 08/14/2021 |
| The structure and properties of MFG-E8 and the In vitro assessment of its toxic effects on myoblast cells. | The structure and properties of MFG-E8 and the In vitro assessment of its toxic effects on myoblast cells.
Li H, Li L, Chen H, Wang R, Ma Y. | 07/3/2021 |
| Knockdown of milk-fat globule EGF factor-8 suppresses glioma progression in GL261 glioma cells by repressing microglial M2 polarization. | Knockdown of milk-fat globule EGF factor-8 suppresses glioma progression in GL261 glioma cells by repressing microglial M2 polarization.
Wu J, Yang H, Cheng J, Zhang L, Ke Y, Zhu Y, Wang C, Zhang X, Zhen X, Zheng LT. | 03/20/2021 |
| The expressions of MFG-E8 in murine and human angiosarcoma (AS) cells were significantly higher than those in melanoma cells, macrophages and endothelial cells. Depletion of MFG-E8 in murine AS cells by siRNA significantly inhibited the formation of capillary-like structures and migration. AS-derived MFG-E8 might enhance tumor growth via angiogenesis and the induction of TAMs in autocrine/paracrine manner. | The significance of tumor cells-derived MFG-E8 in tumor growth of angiosarcoma.
Fujiwara C, Motegi SI, Ohira A, Yamaguchi S, Sekiguchi A, Yasuda M, Nakamura H, Makiguchi T, Yokoo S, Hoshina D, Abe R, Takahashi K, Ishikawa O. | 04/4/2020 |