| MYO10 promotes transzonal projection-dependent germ line-somatic contact during mammalian folliculogenesisdagger. | MYO10 promotes transzonal projection-dependent germ line-somatic contact during mammalian folliculogenesis†.
Granados-Aparici S, Volodarsky-Perel A, Yang Q, Anam S, Tulandi T, Buckett W, Son WY, Younes G, Chung JT, Jin S, Terret ME, Clarke HJ., Free PMC Article | 08/27/2022 |
| Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex. | Cytoneme delivery of Sonic Hedgehog from ligand-producing cells requires Myosin 10 and a Dispatched-BOC/CDON co-receptor complex.
Hall ET, Dillard ME, Stewart DP, Zhang Y, Wagner B, Levine RM, Pruett-Miller SM, Sykes A, Temirov J, Cheney RE, Mori M, Robinson CG, Ogden SK., Free PMC Article | 01/29/2022 |
| Myosin-X is dispensable for spindle morphogenesis and positioning in the mouse oocyte. | Myosin-X is dispensable for spindle morphogenesis and positioning in the mouse oocyte.
Crozet F, Da Silva C, Verlhac MH, Terret ME., Free PMC Article | 09/18/2021 |
| Circ-calm4 Serves as an miR-337-3p Sponge to Regulate Myo10 (Myosin 10) and Promote Pulmonary Artery Smooth Muscle Proliferation. | Circ-calm4 Serves as an miR-337-3p Sponge to Regulate Myo10 (Myosin 10) and Promote Pulmonary Artery Smooth Muscle Proliferation.
Zhang J, Li Y, Qi J, Yu X, Ren H, Zhao X, Xin W, He S, Zheng X, Ma C, Zhang L, Wu B, Zhu D. | 02/27/2021 |
| Myosin X Interaction with KIF13B, a Crucial Pathway for Netrin-1-Induced Axonal Development. | Myosin X Interaction with KIF13B, a Crucial Pathway for Netrin-1-Induced Axonal Development.
Yu HL, Peng Y, Zhao Y, Lan YS, Wang B, Zhao L, Sun D, Pan JX, Dong ZQ, Mei L, Ding YQ, Zhu XJ, Xiong WC., Free PMC Article | 02/20/2021 |
| Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells. | Lack of Myosin X Enhances Osteoclastogenesis and Increases Cell Surface Unc5b in Osteoclast-Lineage Cells.
Wang B, Pan JX, Yu H, Xiong L, Zhao K, Xiong S, Guo JP, Lin S, Sun D, Zhao L, Guo H, Mei L, Xiong WC., Free PMC Article | 08/13/2020 |
| Our current study reveals involvement of Myo10 in murine skin pigmentation. | Myosin 10 is involved in murine pigmentation.
Liakath-Ali K, Vancollie VE, Sequeira I, Lelliott CJ, Watt FM., Free PMC Article | 05/30/2020 |
| involvement of Myo10 not only in melanoblast migration, but also in melanoma development and metastasis. | Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis.
Tokuo H, Bhawan J, Coluccio LM., Free PMC Article | 11/2/2019 |
| Osteoclast differentiation is regulated by Myo10. | Regulation of Osteoclast Differentiation by Myosin X.
Tasca A, Astleford K, Lederman A, Jensen ED, Lee BS, Gopalakrishnan R, Mansky KC., Free PMC Article | 02/23/2019 |
| These results suggest that the lever-arm of full-length myosin-X is flexible enough to processively steps on different actin filaments within the actin bundles of filopodia. This characteristic of myosin-X may facilitate actin filament convergence for filopodia production. | Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directions.
Sato O, Jung HS, Komatsu S, Tsukasaki Y, Watanabe TM, Homma K, Ikebe M., Free PMC Article | 11/10/2018 |
| Reduction in ADD1 protein in NEK1 mutant mice is associated with hyperphosphorylation of ADD1, thereby preventing the interaction with MYO10 during meiotic spindle formation | NIMA-related kinase 1 (NEK1) regulates meiosis I spindle assembly by altering the balance between α-Adducin and Myosin X.
Brieño-Enríquez MA, Moak SL, Holloway JK, Cohen PE., Free PMC Article | 11/4/2017 |
| analysis of phenotypes of Cdc42 and Myo10 deletion that show multiple roles of filopodial dynamics | Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion.
Horsthemke M, Bachg AC, Groll K, Moyzio S, Müther B, Hemkemeyer SA, Wedlich-Söldner R, Sixt M, Tacke S, Bähler M, Hanley PJ., Free PMC Article | 07/15/2017 |
| Myo10 is required for neurogenic cell migration through N-cadherin mediated cell adhesion. | Myo10 is required for neurogenic cell adhesion and migration.
Yu H, Lai M, Guo Y, Yuan L, Lan Y, Wang X, Zhu X. | 04/30/2016 |
| Myo10 is involved in neuronal development both in vitro and in vivo by regulating microtubule stability | Headless Myo10 is a regulator of microtubule stability during neuronal development.
Yu H, Sun D, Wang N, Wang M, Lan Y, Fan W, Zhao Y, Guo W, Zhu X. | 01/16/2016 |
| Results indicate that, in neuronal cells, TNTs can arise from a subset of Myo10-driven dorsal filopodia, independent of its binding to integrins and N-cadherins. | Myo10 is a key regulator of TNT formation in neuronal cells.
Gousset K, Marzo L, Commere PH, Zurzolo C. | 07/5/2014 |
| The study analyzed and cloned 2-kb of the 5'-upstream sequences of mouse full-length Myo10 (fMyo10) and headless Myo10 (hMyo10) to understand the transcriptional regulation of the Myo10 gene. | Cloning, characterization, and promoter analysis of mouse Myo10 gene.
Lai M, Li L, Ju X, Yu H, Zhu X. | 12/28/2013 |
| headless Myo10 can function as a negative regulator of full-length Myo10 and that the two isoforms of Myo10 have opposing roles in axon outgrowth. | Headless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neurons.
Raines AN, Nagdas S, Kerber ML, Cheney RE., Free PMC Article | 10/20/2012 |
| Myo10 was required for neuronal morphological transition during radial neuronal migration in the developmental neocortex | PtdIns (3,4,5) P3 recruitment of Myo10 is essential for axon development.
Yu H, Wang N, Ju X, Yang Y, Sun D, Lai M, Cui L, Sheikh MA, Zhang J, Wang X, Zhu X., Free PMC Article | 09/22/2012 |
| DCC promotes movement of Myo X along basal actin filaments and enhances Myo-X-mediated basal filopodium elongation. | Differential regulation of myosin X movements by its cargos, DCC and neogenin.
Liu Y, Peng Y, Dai PG, Du QS, Mei L, Xiong WC., Free PMC Article | 09/8/2012 |
| Myo10 plays a role in osteoclast attachment and podosome positioning by direct linkage of actin to the microtubule network | Myosin X regulates sealing zone patterning in osteoclasts through linkage of podosomes and microtubules.
McMichael BK, Cheney RE, Lee BS., Free PMC Article | 05/3/2010 |
| Data show that myosin X suppresses adhesion pf GnRH cells to the matrix and decreases their migratory activity. | Involvement of headless myosin X in the motility of immortalized gonadotropin-releasing hormone neuronal cells.
Wang JJ, Fu XQ, Guo YG, Yuan L, Gao QQ, Yu HL, Shi HL, Wang XZ, Xiong WC, Zhu XJ., Free PMC Article | 01/21/2010 |
| Our data indicate that Myo10 is required to guide endothelial migration toward BMP6 gradients via the regulation of filopodial function and amplification of BMP signals. | Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors.
Pi X, Ren R, Kelley R, Zhang C, Moser M, Bohil AB, Divito M, Cheney RE, Patterson C., Free PMC Article | 01/21/2010 |
| The motor function of the two-headed form of myoX is critical for actin reorganization at the leading edge, leading to filopodia formation. | The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.
Tokuo H, Mabuchi K, Ikebe M., Free PMC Article | 01/21/2010 |
| Knock-down of Myo10 by siRNA impaired integrin function in cell adhesion, whereas overexpression of Myo10 stimulated the formation and elongation of filopodia in an integrin-dependent manner. | Myosin-X provides a motor-based link between integrins and the cytoskeleton.
Zhang H, Berg JS, Li Z, Wang Y, Lång P, Sousa AD, Bhaskar A, Cheney RE, Strömblad S. | 01/21/2010 |
| myosin X PH domains have roles in signaling events and in regulating its cellular function | The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblasts.
Mashanov GI, Tacon D, Peckham M, Molloy JE. | 01/21/2010 |