| Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling. | Macrophage neogenin deficiency exacerbates myocardial remodeling and inflammation after acute myocardial infarction through JAK1-STAT1 signaling.
Zhang J, Xu Y, Wei C, Yin Z, Pan W, Zhao M, Ding W, Xu S, Liu J, Yu J, Ye J, Ye D, Qin JJ, Wan J, Wang M., Free PMC Article | 11/18/2023 |
| Down-Regulation of Neogenin Decreases Proliferation and Differentiation of Spermatogonia during the Early Phase of Spermatogenesis. | Down-Regulation of Neogenin Decreases Proliferation and Differentiation of Spermatogonia during the Early Phase of Spermatogenesis.
Park JW, Kim YJ, Lee SJ, Ko JJ, Kim DK, Lee JH., Free PMC Article | 03/3/2023 |
| Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells. | Neogenin pathway positively regulates fibronectin production by glomerular mesangial cells.
Chaudhari S, Yazdizadeh Shotorbani P, Tao Y, Kasetti R, Zode G, Mathis KW, Ma R., Free PMC Article | 07/16/2022 |
| Transsynaptic cerebellin 4-neogenin 1 signaling mediates LTP in the mouse dentate gyrus. | Transsynaptic cerebellin 4-neogenin 1 signaling mediates LTP in the mouse dentate gyrus.
Liakath-Ali K, Polepalli JS, Lee SJ, Cloutier JF, Südhof TC., Free PMC Article | 05/21/2022 |
| Linking cortical astrocytic neogenin deficiency to the development of Moyamoya disease-like vasculopathy. | Linking cortical astrocytic neogenin deficiency to the development of Moyamoya disease-like vasculopathy.
Ren X, Yao LL, Pan JX, Zhang JS, Mei L, Wang YG, Xiong WC. | 01/22/2022 |
| Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response. | Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response.
Sun D, Tan ZB, Sun XD, Liu ZP, Chen WB, Milibari L, Ren X, Yao LL, Lee D, Shen C, Pan JX, Huang ZH, Mei L, Xiong WC., Free PMC Article | 12/11/2021 |
| Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice. | Hepatocyte neogenin is required for hemojuvelin-mediated hepcidin expression and iron homeostasis in mice.
Enns CA, Jue S, Zhang AS., Free PMC Article | 12/4/2021 |
| RGMa can induce skeletal muscle cell hyperplasia via association with neogenin signalling pathway. | RGMa can induce skeletal muscle cell hyperplasia via association with neogenin signalling pathway.
do Carmo Costa A, Copola AGL, Carvalho E Souza C, Nogueira JM, Silva GAB, Jorge EC. | 12/4/2021 |
| Astrocytic neogenin/netrin-1 pathway promotes blood vessel homeostasis and function in mouse cortex. | Astrocytic neogenin/netrin-1 pathway promotes blood vessel homeostasis and function in mouse cortex.
Yao LL, Hu JX, Li Q, Lee D, Ren X, Zhang JS, Sun D, Zhang HS, Wang YG, Mei L, Xiong WC., Free PMC Article | 02/20/2021 |
| Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation. | Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.
Lin S, Liu W, Chen CL, Sun D, Hu JX, Li L, Ye J, Mei L, Xiong WC., Free PMC Article | 02/13/2021 |
| Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. | Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1.
Renders S, Svendsen AF, Panten J, Rama N, Maryanovich M, Sommerkamp P, Ladel L, Redavid AR, Gibert B, Lazare S, Ducarouge B, Schönberger K, Narr A, Tourbez M, Dethmers-Ausema B, Zwart E, Hotz-Wagenblatt A, Zhang D, Korn C, Zeisberger P, Przybylla A, Sohn M, Mendez-Ferrer S, Heikenwälder M, Brune M, Klimmeck D, Bystrykh L, Frenette PS, Mehlen P, de Haan G, Cabezas-Wallscheid N, Trumpp A., Free PMC Article | 02/6/2021 |
| Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration. | Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration.
Charish J, Shabanzadeh AP, Chen D, Mehlen P, Sethuramanujam S, Harada H, Bonilha VL, Awatramani G, Bremner R, Monnier PP., Free PMC Article | 01/2/2021 |
| Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signaling. | Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling.
Huyghe A, Furlan G, Ozmadenci D, Galonska C, Charlton J, Gaume X, Combémorel N, Riemenschneider C, Allègre N, Zhang J, Wajda P, Rama N, Vieugué P, Durand I, Brevet M, Gadot N, Imhof T, Merrill BJ, Koch M, Mehlen P, Chazaud C, Meissner A, Lavial F. | 04/25/2020 |
| Investigated role of neogenin (NEO1) and homeobox B5 (Hoxb5) in differentiation of a specific subpopulation of mouse hematopoietic stem cells. | Neogenin-1 distinguishes between myeloid-biased and balanced Hoxb5(+) mouse long-term hematopoietic stem cells.
Gulati GS, Zukowska M, Noh JJ, Zhang A, Wesche DJ, Sinha R, George BM, Weissman IL, Szade K., Free PMC Article | 04/11/2020 |
| Ablation of Neogenin in the basolateral amygdala impaired fear memory and reduced EPSP frequency. | Neogenin in Amygdala for Neuronal Activity and Information Processing.
Sun XD, Chen WB, Sun D, Huang J, Li YQ, Pan JX, Wang YN, Zhao K, Dong ZQ, Wang HS, Xiong L, Xuan A, Zhao ST, Pillai A, Xiong WC, Mei L., Free PMC Article | 10/12/2019 |
| Together, these findings identify a crucial role for Neo1 in regulating tissue regeneration and resolution of inflammation, and determined Neo1 to be a predictor of morbidity and mortality in critically ill children affected by clinical inflammation. | Inhibition of neogenin fosters resolution of inflammation and tissue regeneration.
Schlegel M, Körner A, Kaussen T, Knausberg U, Gerber C, Hansmann G, Jónasdóttir HS, Giera M, Mirakaj V., Free PMC Article | 09/14/2019 |
| up and downregulation of neogenin signaling was associated with mitochondrial activity in embryos. | Neogenin regulates mitochondrial activity in pre-implantation mouse embryos.
Choi KH, Hong SH, Lee HR, Lee HT, Lee JH, Lee SJ. | 12/16/2017 |
| The results indicate that RGMB-neogenin-mediated cell-cell interactions between newly born neurons and progenitor cells control the ratio of glia and neurons produced in the developing olfactory epithelium. | RGMB and neogenin control cell differentiation in the developing olfactory epithelium.
Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF. | 09/23/2017 |
| Thus, our findings identify an unrecognized function of neogenin in mouse neocortical astrocyte differentiation, and suggest a signaling pathway, BMP2-neogenin-YAP-Smad1, underlying astrogliogenesis in developing mouse neocortex. | Neogenin Promotes BMP2 Activation of YAP and Smad1 and Enhances Astrocytic Differentiation in Developing Mouse Neocortex.
Huang Z, Sun D, Hu JX, Tang FL, Lee DH, Wang Y, Hu G, Zhu XJ, Zhou J, Mei L, Xiong WC., Free PMC Article | 07/8/2017 |
| Results indicate that an efficient induction of hepcidin expression by hemojuvelin (HJV) requires its interaction with neogenin. | Neogenin Facilitates the Induction of Hepcidin Expression by Hemojuvelin in the Liver.
Zhao N, Maxson JE, Zhang RH, Wahedi M, Enns CA, Zhang AS., Free PMC Article | 12/17/2016 |
| Neogenin acts to synchronize neuroblast migration and terminal differentiation through the regulation of neuroblast cell cycle kinetics within the neurogenic microenvironment of the RMS. | The Netrin/RGM receptor, Neogenin, controls adult neurogenesis by promoting neuroblast migration and cell cycle exit.
O'Leary CJ, Bradford D, Chen M, White A, Blackmore DG, Cooper HM. | 09/26/2015 |
| these results highlight Neogenin1 as a novel downstream effector of the Sonic Hedgehog pathway in medulloblastoma | Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression.
Milla LA, Arros A, Espinoza N, Remke M, Kool M, Taylor MD, Pfister SM, Wainwright BJ, Palma V. | 12/7/2013 |
| Strong expression of RGMa, RGMb and Neogenin protein was found on several major axon tracts such as the primary olfactory projections, anterior commissure and fasciculus retroflexus. | Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain.
van den Heuvel DM, Hellemons AJ, Pasterkamp RJ., Free PMC Article | 08/31/2013 |
| neogenin appears to suppress Myo X movement on the basal side, but increases its movement towards the apical and dorsal side of a cell, promoting dorsal filopodium formation and growth | Differential regulation of myosin X movements by its cargos, DCC and neogenin.
Liu Y, Peng Y, Dai PG, Du QS, Mei L, Xiong WC., Free PMC Article | 09/8/2012 |
| guidance receptor neogenin holds crucial importance for the propagation of an acute inflammatory response and further define mechanisms shared between the nervous and the immune system. | The axonal guidance receptor neogenin promotes acute inflammation.
König K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V., Free PMC Article | 08/4/2012 |