Epigenetic mechanisms differentially regulate blood pressure and renal dysfunction in male and female Npr1 haplotype mice.
Kumar P, Neelamegam K, Ramasamy C, Samivel R, Xia H, Kapusta DR, Pandey KN., Free PMC Article

Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi.
Sugioka S, Yamada H, Ishii A, Kato Y, Yamada R, Mori KP, Ohno S, Handa T, Ikushima A, Ishimura T, Osaki K, Tokudome T, Matsusaka T, Nebreda AR, Yanagita M, Yokoi H.

The landscape of N6-methyladenosine modification patterns and altered transcript profiles in the cardiac-specific deletion of natriuretic peptide receptor A.
Shen X, Chang P, Zhang X, Zhang J, Wang X, Quan Z, Wang P, Liu T, Niu Y, Zheng R, Chen B, Yu J.

Lack of NPR1 Increases Vascular Endothelial Adhesion through Induction of Integrin Beta 4.
Liu H, Liu J, Long C, Chen L, Zhan W, Xiao W, Gong X, Liu M, Tian XL, Chen S., Free PMC Article

Genetic Disruption of Guanylyl Cyclase/Natriuretic Peptide Receptor-A Triggers Differential Cardiac Fibrosis and Disorders in Male and Female Mutant Mice: Role of TGF-β1/SMAD Signaling Pathway.
Subramanian U, Ramasamy C, Ramachandran S, Oakes JM, Gardner JD, Pandey KN., Free PMC Article

Endothelial Natriuretic Peptide Receptor 1 Play Crucial Role for Acute and Chronic Blood Pressure Regulation by Atrial Natriuretic Peptide.
Tokudome T, Otani K, Mao Y, Jensen LJ, Arai Y, Miyazaki T, Sonobe T, Pearson JT, Osaki T, Minamino N, Ishida J, Fukamizu A, Kawakami H, Onozuka D, Nishimura K, Miyazato M, Nishimura H.

BNP facilitates NMB-encoded histaminergic itch via NPRC-NMBR crosstalk.
Meng QT, Liu XY, Liu XT, Liu J, Munanairi A, Barry DM, Liu B, Jin H, Sun Y, Yang Q, Gao F, Wan L, Peng J, Jin JH, Shen KF, Kim R, Yin J, Tao A, Chen ZF., Free PMC Article

Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice.
Wagner BM, Robinson JW, Healy CL, Gauthier M, Dickey DM, Yee SP, Osborn JW, O'Connell TD, Potter LR., Free PMC Article

GRPR/Extracellular Signal-Regulated Kinase and NPRA/Extracellular Signal-Regulated Kinase Signaling Pathways Play a Critical Role in Spinal Transmission of Chronic Itch.
Liu X, Wang Y, Tao T, Zeng L, Wang D, Wen Y, Li Y, Zhao Z, Tao A.

Cardiac‑specific deletion of natriuretic peptide receptor A induces differential myocardial expression of circular RNA and mRNA molecules involved in metabolism in mice.
Chen B, Chang P, Shen X, Zhang X, Zhang J, Wang X, Yu J., Free PMC Article

Spinal GRPR and NPRA Contribute to Chronic Itch in a Murine Model of Allergic Contact Dermatitis.
Liu X, Wang D, Wen Y, Zeng L, Li Y, Tao T, Zhao Z, Tao A.

Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates renal (pro) renin receptor expression in Npr1 null mutant mice.
Periyasamy R, Das S, Pandey KN., Free PMC Article

Genetic disruption of Npr1 depletes regulatory T cells and provokes high levels of proinflammatory cytokines and fibrosis in the kidneys of female mutant mice.
Gogulamudi VR, Mani I, Subramanian U, Pandey KN., Free PMC Article

Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function.
Pandey KN., Free PMC Article

Natriuretic peptide receptor guanylyl cyclase-A pathway counteracts glomerular injury evoked by aldosterone through p38 mitogen-activated protein kinase inhibition.
Kato Y, Mori K, Kasahara M, Osaki K, Ishii A, Mori KP, Toda N, Ohno S, Kuwabara T, Tokudome T, Kishimoto I, Saleem MA, Matsusaka T, Nakao K, Mukoyama M, Yanagita M, Yokoi H., Free PMC Article

Regulation of natriuretic peptides postprandially in vivo and of their receptors in adipocytes by fatty acids in vitro.
Schmid A, Albrecht J, Brock J, Koukou M, Arapogianni E, Schäffler A, Karrasch T.

β Cell-specific deletion of guanylyl cyclase A, the receptor for atrial natriuretic peptide, accelerates obesity-induced glucose intolerance in mice.
Tauscher S, Nakagawa H, Völker K, Werner F, Krebes L, Potapenko T, Doose S, Birkenfeld AL, Baba HA, Kuhn M., Free PMC Article

Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice.
Subramanian U, Kumar P, Mani I, Chen D, Kessler I, Periyasamy R, Raghavaraju G, Pandey KN., Free PMC Article

Natriuretic peptide receptor A inhibition suppresses gastric cancer development through reactive oxygen species-mediated G2/M cell cycle arrest and cell death.
Li Z, Wang JW, Wang WZ, Zhi XF, Zhang Q, Li BW, Wang LJ, Xie KL, Tao JQ, Tang J, Wei S, Zhu Y, Xu H, Zhang DC, Yang L, Xu ZK.

Klf10 deficiency in mice exacerbates pulmonary inflammation by increasing expression of the proinflammatory molecule NPRA.
Huang LT, Chang HW, Wu MJ, Lai YT, Wu WC, Yu WCY, Chang VHS.

Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in Npr1 haplotype male mice.
Kumar P, Gogulamudi VR, Periasamy R, Raghavaraju G, Subramanian U, Pandey KN., Free PMC Article

Loss of inhibition by brain natriuretic peptide over P2X3 receptors contributes to enhanced spike firing of trigeminal ganglion neurons in a mouse model of familial hemiplegic migraine type-1.
Marchenkova A, van den Maagdenberg AM, Nistri A.

Transforming growth factor β1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of δEF1.
Sen A, Kumar P, Garg R, Lindsey SH, Katakam PV, Bloodworth M, Pandey KN., Free PMC Article

Systemic, but not cardiomyocyte-specific, deletion of the natriuretic peptide receptor guanylyl cyclase A increases cardiomyocyte number in neonatal mice.
Schipke J, Roloff K, Kuhn M, Mühlfeld C.

Importance of Endogenous Atrial and Brain Natriuretic Peptides in Murine Embryonic Vascular and Organ Development.
Tokudome T, Kishimoto I, Shindo T, Kawakami H, Koyama T, Otani K, Nishimura H, Miyazato M, Kohno M, Nakao K, Kangawa K.