Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells.
Wu X, Zhu H, Liu J, Ouyang S, Lyu Z, Jin Y, Chen X, Meng Q.

Investigation of cryptic JAG1 splice variants as a cause of Alagille syndrome and performance evaluation of splice predictor tools.
Keefer-Jacques E, Valente N, Jacko AM, Matwijec G, Reese A, Tekriwal A, Loomes KM, Spinner NB, Gilbert MA., Free PMC Article

Jag1/2 maintain esophageal homeostasis and suppress foregut tumorigenesis by restricting the basal progenitor cell pool.
Huang H, Jiang Y, Liu J, Luo D, Yuan J, Mu R, Yu X, Sun D, Lin J, Chen Q, Li X, Jiang M, Xu J, Chu B, Yin C, Zhang L, Ye Y, Cao B, Wang Q, Zhang Y., Free PMC Article

Hypermethylation leads to the loss of HOXA5, resulting in JAG1 expression and NOTCH signaling contributing to kidney fibrosis.
Xiao X, Wang W, Guo C, Wu J, Zhang S, Shi H, Kwon S, Chen J, Dong Z.

Splicing factor ESRP1 derived circ_0068162 promotes the progression of oral squamous cell carcinoma via the miR-186/JAG axis.
Chen S, Zong Y, Hou Z, Deng Z, Xia Z.

Novel JAG1 variants leading to Alagille syndrome in two Chinese cases.
Feng X, Ping J, Gao S, Han D, Song W, Li X, Tao Y, Wang L., Free PMC Article

Jagged1 contained in MSC-derived small extracellular vesicles promotes squamous differentiation of cervical cancer by activating NOTCH pathway.
Li W, Zhang X, Gao T, Liu L, Zhang C, Yang H, Xie J, Pan W, Deng DYB, Zhang C, Li T., Free PMC Article

Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion.
Kim JY, Hong N, Park S, Ham SW, Kim EJ, Kim SO, Jang J, Kim Y, Kim JK, Kim SC, Park JW, Kim H., Free PMC Article

Jagged1 Acts as an RBP-J Target and Feedback Suppresses TNF-Mediated Inflammatory Osteoclastogenesis.
Ng C, Qin Y, Xia Y, Hu X, Zhao B., Free PMC Article

Annexin A2 Stabilizes Oncogenic JAG1 Intracellular Domain by Inhibiting Proteasomal Degradation in Glioblastoma Cells.
Ham SW, Kim JY, Seo S, Hong N, Park MJ, Kim Y, Jang J, Park S, Lee SJ, Kim JK, Kim EJ, Kim SO, Kim SC, Park JW, Kim H., Free PMC Article

Hematopoietic Jagged1 is a fetal liver niche factor required for functional maturation and engraftment of fetal hematopoietic stem cells.
Shao L, Paik NY, Sanborn MA, Bandara T, Vijaykumar A, Sottoriva K, Rehman J, Nombela-Arrieta C, Pajcini KV., Free PMC Article

[JAG1 affects monocytes-macrophages to reshape the pre-metastatic niche of triple-negative breast cancer through LncRNA MALAT1 in exosomes].
Xu M, Shi Y, Liu J, Wu M, Zhang F, He Z, Tang M., Free PMC Article

Aberrant expression of PELI1 caused by Jagged1 accelerates the malignant phenotype of pancreatic cancer.
Zhou W, Hu Y, Wang B, Yuan L, Ma J, Meng X.

YY1/miR-140-5p/Jagged1/Notch axis mediates cartilage progenitor/stem cells fate reprogramming in knee osteoarthritis.
Chen Y, Liao G, Ma T, Li L, Yang J, Shen B, Lu Y, Si H.

JAG1 is associated with the prognosis and metastasis in breast cancer.
Qiao X, Ma B, Sun W, Zhang N, Liu Y, Jia L, Liu C., Free PMC Article

Isolated aneurysmal disease as an underestimated finding in individuals with JAG1 pathogenic variants.
Rodrigues Bento J, Krebsová A, Van Gucht I, Valdivia Callejon I, Van Berendoncks A, Votypka P, Luyckx I, Peldova P, Laga S, Havelka M, Van Laer L, Trunecka P, Boeckx N, Verstraeten A, Macek M, Meester JAN, Loeys B., Free PMC Article

Indirect Immobilised Jagged-1 Enhances Matrisome Proteins Associated with Osteogenic Differentiation of Human Dental Pulp Stem Cells: A Proteomic Study.
Chansaenroj A, Kornsuthisopon C, Roytrakul S, Phothichailert S, Rochanavibhata S, Fournier BPJ, Srithanyarat SS, Nowwarote N, Osathanon T., Free PMC Article

An N-glycan on the C2 domain of JAGGED1 is important for Notch activation.
Meng Y, Sanlidag S, Jensen SA, Burnap SA, Struwe WB, Larsen AH, Feng X, Mittal S, Sansom MSP, Sahlgren C, Handford PA.

JAG1-NOTCH4 mechanosensing drives atherosclerosis.
Souilhol C, Tardajos Ayllon B, Li X, Diagbouga MR, Zhou Z, Canham L, Roddie H, Pirri D, Chambers EV, Dunning MJ, Ariaans M, Li J, Fang Y, Jørgensen HF, Simons M, Krams R, Waltenberger J, Fragiadaki M, Ridger V, De Val S, Francis SE, Chico TJ, Serbanovic-Canic J, Evans PC., Free PMC Article

[JAG1 promotes migration, invasion, and adhesion of triple-negative breast cancer cells by promoting angiogenesis].
Liu J, Shi Y, Wu M, Xu M, Zhang F, He Z, Tang M., Free PMC Article

Leptin modulated microRNA-628-5p targets Jagged-1 and inhibits prostate cancer hallmarks.
Rios-Colon L, Chijioke J, Niture S, Afzal Z, Qi Q, Srivastava A, Ramalinga M, Kedir H, Cagle P, Arthur E, Sharma M, Moore J, Deep G, Suy S, Collins SP, Kumar D., Free PMC Article

Identifying potential regulators of JAGGED1 expression in portal mesenchymal cells.
Nishino T, Yoshihara M, Nakayama T, Tsuchiya T, Tahara S, Ozaki H, Takahashi S., Free PMC Article

A novel mechanism of the lncRNA PTTG3P/miR-142-5p/JAG1 axis modulating tongue cancer cell phenotypes through the Notch1 signaling.
Zhang T, Liu X, Su K, Zheng Q, Liu P, Xu Z, Zhang Y.

IncRNA XIST Targets miR-124/JAG1 via CeRNA Mechanism to Facilitate the Migration and Proliferation of Tongue Squamous Cell Carcinoma.
Gao S, Yu J, Shan Z, Zuo L, Huang W, Gan L, Tian H.

Evaluation of the Genetic Association and Expressions of Notch-2 /Jagged-1 in Patients with Type 2 Diabetes Mellitus.
Al-Awaida WJ, Hameed WS, Al Hassany HJ, Al-Dabet MM, Al-Bawareed O, Hadi NR., Free PMC Article