| Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study. | Sigma-1 Receptors Control Neuropathic Pain and Peripheral Neuroinflammation After Nerve Injury in Female Mice: A Transcriptomic Study.
Ruiz-Cantero MC, Entrena JM, Artacho-Cordón A, Huerta MÁ, Portillo-Salido E, Nieto FR, Baeyens JM, Costigan M, González-Cano R, Cobos EJ. | 10/1/2024 |
| Activation of the sigma-1 receptor ameliorates neuronal ferroptosis via IRE1alpha after spinal cord injury. | Activation of the sigma-1 receptor ameliorates neuronal ferroptosis via IRE1α after spinal cord injury.
Tan R, Sui C, Diao Y, Shi G, Hu X, Hao Z, Li C, Hao M, Xie M, Zhu T. | 06/27/2024 |
| Genetic and Neuroimaging Analysis of SIGMAR1 for Frontotemporal Dementia. | Genetic and Neuroimaging Analysis of SIGMAR1 for Frontotemporal Dementia.
Che XQ, Lin GZ, Liu XH, Wang G, Zhao QH, Ren RJ. | 09/21/2023 |
| Sigma-1 receptor expression in a subpopulation of lumbar spinal cord microglia in response to peripheral nerve injury. | Sigma-1 receptor expression in a subpopulation of lumbar spinal cord microglia in response to peripheral nerve injury.
Schonfeld E, Johnstone TM, Haider G, Shah A, Marianayagam NJ, Biswal S, Veeravagu A., Free PMC Article | 09/13/2023 |
| The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants. | The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants.
Hosszu A, Toth AR, Lakat T, Stepanova G, Antal Z, Wagner LJ, Szabo AJ, Fekete A., Free PMC Article | 08/19/2023 |
| Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1. | Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.
Huang R, Cai L, Ma X, Shen K. | 08/11/2023 |
| Pharmacological Analysis of GABAA Receptor and Sigma1R Chaperone Interaction: Research Report I-Investigation of the Anxiolytic, Anticonvulsant and Hypnotic Effects of Allosteric GABAA Receptors' Ligands. | Pharmacological Analysis of GABA(A) Receptor and Sigma1R Chaperone Interaction: Research Report I-Investigation of the Anxiolytic, Anticonvulsant and Hypnotic Effects of Allosteric GABA(A) Receptors' Ligands.
Voronin MV, Shangin SV, Litvinova SA, Abramova EV, Kurbanov RD, Rybina IV, Vakhitova YV, Seredenin SB., Free PMC Article | 06/15/2023 |
| Sigma 1 receptor activation improves retinal structure and function in the Rho[P23H/+] mouse model of autosomal dominant retinitis pigmentosa. | Sigma 1 receptor activation improves retinal structure and function in the Rho(P23H/+) mouse model of autosomal dominant retinitis pigmentosa.
Barwick SR, Xiao H, Wolff D, Wang J, Perry E, Marshall B, Smith SB., Free PMC Article | 05/1/2023 |
| Specific detection and deletion of the sigma-1 receptor widely expressed in neurons and glial cells in vivo. | Specific detection and deletion of the sigma-1 receptor widely expressed in neurons and glial cells in vivo.
Liu Q, Guo Q, Fang LP, Yao H, Scheller A, Kirchhoff F, Huang W. | 03/30/2023 |
| Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis. | Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.
Watanabe S, Horiuchi M, Murata Y, Komine O, Kawade N, Sobue A, Yamanaka K. | 03/23/2023 |
| The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors. | The sigma-1 receptor curtails endogenous opioid analgesia during sensitization of TRPV1 nociceptors.
Ruiz-Cantero MC, Cortés-Montero E, Jain A, Montilla-García Á, Bravo-Caparrós I, Shim J, Sánchez-Blázquez P, Woolf CJ, Baeyens JM, Cobos EJ. | 03/20/2023 |
| Sigma-1 receptor-regulated efferocytosis by infiltrating circulating macrophages/microglial cells protects against neuronal impairments and promotes functional recovery in cerebral ischemic stroke. | Sigma-1 receptor-regulated efferocytosis by infiltrating circulating macrophages/microglial cells protects against neuronal impairments and promotes functional recovery in cerebral ischemic stroke.
Zhang G, Li Q, Tao W, Qin P, Chen J, Yang H, Chen J, Liu H, Dai Q, Zhen X., Free PMC Article | 02/15/2023 |
| Sigma-1 Receptor as a Protective Factor for Diabetes-Associated Cognitive Dysfunction via Regulating Astrocytic Endoplasmic Reticulum-Mitochondrion Contact and Endoplasmic Reticulum Stress. | Sigma-1 Receptor as a Protective Factor for Diabetes-Associated Cognitive Dysfunction via Regulating Astrocytic Endoplasmic Reticulum-Mitochondrion Contact and Endoplasmic Reticulum Stress.
Du M, Jiang T, He S, Cheng B, Zhang X, Li L, Yang L, Gao W, Li Y, Wang Q., Free PMC Article | 01/21/2023 |
| Sigma-1 receptor attenuates osteoclastogenesis by promoting ER-associated degradation of SERCA2. | Sigma-1 receptor attenuates osteoclastogenesis by promoting ER-associated degradation of SERCA2.
Wei X, Zheng Z, Feng Z, Zheng L, Tao S, Zheng B, Huang B, Zhang X, Liu J, Chen Y, Zong W, Shan Z, Fan S, Chen J, Zhao F., Free PMC Article | 07/16/2022 |
| Sigma-1 Receptor Alleviates Airway Inflammation and Airway Remodeling Through AMPK/CXCR4 Signal Pathway. | Sigma-1 Receptor Alleviates Airway Inflammation and Airway Remodeling Through AMPK/CXCR4 Signal Pathway.
Jiang T, Zhao D, Zheng Z, Li Z. | 05/21/2022 |
| Visualization of Dynamic Expression of Myocardial Sigma-1 Receptor After Myocardial Ischemia and Reperfusion Using Radioiodine-Labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) Imaging. | Visualization of Dynamic Expression of Myocardial Sigma-1 Receptor After Myocardial Ischemia and Reperfusion Using Radioiodine-Labeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) Imaging.
Wakabayashi H, Taki J, Mori H, Hiromasa T, Akatani N, Inaki A, Kozaka T, Shiba K, Ogawa K, Kinuya S. | 04/23/2022 |
| Activation of the sigma-1 receptor attenuates blood-brain barrier disruption by inhibiting amyloid deposition in Alzheimer's disease mice. | Activation of the sigma-1 receptor attenuates blood-brain barrier disruption by inhibiting amyloid deposition in Alzheimer's disease mice.
An Y, Qi Y, Li Y, Li Z, Yang C, Jia D. | 04/23/2022 |
| Molecular Characterization of Skeletal Muscle Dysfunction in Sigma 1 Receptor (Sigmar1) Knockout Mice. | Molecular Characterization of Skeletal Muscle Dysfunction in Sigma 1 Receptor (Sigmar1) Knockout Mice.
Aishwarya R, Abdullah CS, Remex NS, Alam S, Morshed M, Nitu S, Hartman B, King J, Bhuiyan MAN, Orr AW, Kevil CG, Bhuiyan MS., Free PMC Article | 02/19/2022 |
| The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models. | The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models.
Naia L, Ly P, Mota SI, Lopes C, Maranga C, Coelho P, Gershoni-Emek N, Ankarcrona M, Geva M, Hayden MR, Rego AC., Free PMC Article | 02/5/2022 |
| Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection. | Sigma-1 receptor regulates mitophagy in dopaminergic neurons and contributes to dopaminergic protection.
Wang M, Wan C, He T, Han C, Zhu K, Waddington JL, Zhen X. | 02/5/2022 |
| Intestinal inflammation-associated hypersensitivity is attenuated in a DSS model of colitis in Sigma-1 knockout C57BL/6 mice. | Intestinal inflammation-associated hypersensitivity is attenuated in a DSS model of colitis in Sigma-1 knockout C57BL/6 mice.
López-Estévez S, Gris G, de la Puente B, Carceller A, Martínez V. | 01/29/2022 |
| Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures. | Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures.
Vavers E, Zvejniece B, Stelfa G, Svalbe B, Vilks K, Kupats E, Mezapuke R, Lauberte L, Dambrova M, Zvejniece L. | 01/1/2022 |
| Sigma receptor knockdown augments dysfunction and apoptosis of beta cells induced by palmitate. | Sigma receptor knockdown augments dysfunction and apoptosis of beta cells induced by palmitate.
Ke M, He G, Wang H, Cheng S, Xu Y., Free PMC Article | 11/22/2021 |
| Sigma-1 receptor ablation impedes adipocyte-like differentiation of mouse embryonic fibroblasts. | Sigma-1 receptor ablation impedes adipocyte-like differentiation of mouse embryonic fibroblasts.
Yang H, Shen H, Li J, Stanford KI, Guo LW., Free PMC Article | 10/23/2021 |
| Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma. | Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma.
Li L, He S, Liu Y, Yorio T, Ellis DZ., Free PMC Article | 10/2/2021 |