| Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis. | Effect of genetic variation in Notch regulator DTX1 on SCLC prognosis compared with the effect on NSCLC prongosis.
Yoo SS, Lee JH, Hong MJ, Choi JE, Kang HG, Do SK, Kim JH, Baek SA, Choi SH, Lee WK, Lee YH, Seo H, Lee J, Lee SY, Cha SI, Kim CH, Park JY., Free PMC Article | 11/22/2021 |
| DTX1 rs1732786 single nucleotide polymorphism is associated with lung Cancer. | Genetic Variant of Notch Regulator DTX1 Predicts Survival After Lung Cancer Surgery.
Lee JH, Shin KM, Lee SY, Hong MJ, Choi JE, Kang HG, Do SK, Lee WK, Lee EB, Seok Y, Jeong JY, Yoo SS, Lee J, Cha SI, Kim CH, Cho S, Jheon S, Kim YC, Oh IJ, Na KJ, Kim MS, Lee JM, Yang HC, Jung CY, Park CK, Lee MK, Kim DK, Park JY. | 02/15/2020 |
| frameshift mutations in DTX1 and NLRC5, two genes involved in immune regulation, were identified in a family with familial pityriasis rubra pilaris. | Immune-regulatory genes as possible modifiers of familial pityriasis rubra pilaris - lessons from a family with PRP and psoriasis.
Spoerri I, Herms S, Eytan O, Sarig O, Heinimann K, Sprecher E, Itin PH, Burger B. | 08/24/2019 |
| DTX1 is an E3 ligase for c-FLIP in gastric cancer cells. | c-FLIP is a target of the E3 ligase deltex1 in gastric cancer.
Hsu TS, Mo ST, Hsu PN, Lai MZ., Free PMC Article | 08/3/2019 |
| Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma | Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma.
Meriranta L, Pasanen A, Louhimo R, Cervera A, Alkodsi A, Autio M, Taskinen M, Rantanen V, Karjalainen-Lindsberg ML, Holte H, Delabie J, Lehtonen R, Hautaniemi S, Leppä S., Free PMC Article | 09/15/2018 |
| PI5P4Kgamma positively regulates the DTX1-mediated Notch pathway by promoting receptor recycling | PI5P4Kγ functions in DTX1-mediated Notch signaling.
Zheng L, Conner SD., Free PMC Article | 08/11/2018 |
| Data indicate that decreased expression of deltex E3 ubiquitin ligase 1 (DTX1) in head and neck squamous cell carcinoma (HNSCC) tumors maybe associated with NOTCH pathway activation and increased migration potential. | Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC.
Gaykalova DA, Zizkova V, Guo T, Tiscareno I, Wei Y, Vatapalli R, Hennessey PT, Ahn J, Danilova L, Khan Z, Bishop JA, Gutkind JS, Koch WM, Westra WH, Fertig EJ, Ochs MF, Califano JA., Free PMC Article | 09/2/2017 |
| Two SNPs (rs2384077 and rs10744794) in an intron of DTX1 and the linkage disequilibrium (LD) block are significantly associated with the immune response to HBV vaccination. | Deltex1 Polymorphisms Are Associated with Hepatitis B Vaccination Non-Response in Southwest China.
Xie B, Zhang P, Liu M, Zeng W, Yang J, Liu H., Free PMC Article | 07/30/2016 |
| this study reports the identification of two new hGIP-interacting partners, DTX1 and STAU1. | New partner proteins containing novel internal recognition motif for human glutaminase interacting protein (hGIP).
Zencir S, Banerjee M, Dobson MJ, Ayaydin F, Fodor EA, Topcu Z, Mohanty S., Free PMC Article | 09/21/2013 |
| characterization of two genes expressed in centroblasts of human tonsils: deltex (Drosophila) homolog 1 (DTX1), which is related to the Notch pathway and a new Kelch-like protein, KLHL6 | Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells.
Gupta-Rossi N, Storck S, Griebel PJ, Reynaud CA, Weill JC, Dahan A. | 01/21/2010 |
| It is reported that BBAP and the human family of DTX proteins (DTX1, DTX2, and DTX3) function as E3 ligases based on their capacity for self-ubiquitination. | The BAL-binding protein BBAP and related Deltex family members exhibit ubiquitin-protein isopeptide ligase activity.
Takeyama K, Aguiar RC, Gu L, He C, Freeman GJ, Kutok JL, Aster JC, Shipp MA. | 06/9/2005 |