| PRDX1 inhibits ferroptosis by binding to Cullin-3 as a molecular chaperone in colorectal cancer. | PRDX1 inhibits ferroptosis by binding to Cullin-3 as a molecular chaperone in colorectal cancer.
Song Y, Wang X, Sun Y, Yu N, Tian Y, Han J, Qu X, Yu X., Free PMC Article | 10/22/2024 |
| The interaction of PRDX1 with Cofilin promotes oral squamous cell carcinoma metastasis. | The interaction of PRDX1 with Cofilin promotes oral squamous cell carcinoma metastasis.
Shen Y, You Z, Li L, Tang X, Shan X. | 09/11/2024 |
| Peroxiredoxin 1 promotes proliferation and inhibits differentiation of MC3T3-E1 cells via AKT1 / NF-kappaB signaling pathway. | Peroxiredoxin 1 promotes proliferation and inhibits differentiation of MC3T3-E1 cells via AKT1 / NF-κB signaling pathway.
Du J, Zhou W, Sun Z, Zhang W, Luo W, Liu S. | 06/27/2024 |
| Hspb1 protects against severe acute pancreatitis by attenuating apoptosis and ferroptosis via interacting with Anxa2 to restore the antioxidative activity of Prdx1. | Hspb1 protects against severe acute pancreatitis by attenuating apoptosis and ferroptosis via interacting with Anxa2 to restore the antioxidative activity of Prdx1.
He J, Hou X, Wu J, Wang K, Qi X, Wei Z, Sun Y, Wang C, Yao H, Liu K., Free PMC Article | 03/15/2024 |
| DDAH1 recruits peroxiredoxin 1 and sulfiredoxin 1 to preserve its activity and regulate intracellular redox homeostasis. | DDAH1 recruits peroxiredoxin 1 and sulfiredoxin 1 to preserve its activity and regulate intracellular redox homeostasis.
Yuan J, Yu Z, Zhang P, Luo K, Xu Y, Lan T, Zhang M, Chen Y, Lu Z., Free PMC Article | 02/28/2024 |
| Hepatocytes-derived Prdx1 regulates macrophage phenotypes via TLR4 activation in acute liver injury. | Hepatocytes-derived Prdx1 regulates macrophage phenotypes via TLR4 activation in acute liver injury.
Zhang Y, Zhang X, Zhang M, Zhang F, Chen T, Zha J, Shen Q, Wang D, Hou C. | 01/29/2024 |
| Extracellular Prdx1 mediates bacterial infection and inflammatory bone diseases. | Extracellular Prdx1 mediates bacterial infection and inflammatory bone diseases.
Kang JH, Lee HY, Kim NY, Lee DS, Yim M. | 10/30/2023 |
| PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice. | PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice.
Bai Z, Yin W, Liu R, Tang M, Shi X, Luo C, Xie X., Free PMC Article | 09/11/2023 |
| Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-kappaB signaling. | Peroxiredoxin 1 aggravates acute kidney injury by promoting inflammation through Mincle/Syk/NF-κB signaling.
Li S, Zhang Y, Lu R, Lv X, Lei Q, Tang D, Dai Q, Deng Z, Liao X, Tu S, Yang H, Xie Y, Meng J, Yuan Q, Qin J, Pu J, Peng Z, Tao L. | 07/25/2023 |
| PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo. | PRDX1 negatively regulates bleomycin-induced pulmonary fibrosis via inhibiting the epithelial-mesenchymal transition and lung fibroblast proliferation in vitro and in vivo.
Sun HN, Ren CX, Lee DH, Wang WH, Guo XY, Hao YY, Wang XM, Zhang HN, Xiao WQ, Li N, Cong J, Han YH, Kwon T., Free PMC Article | 06/16/2023 |
| Extracellular vesicles from bone marrow stromal cells reduce the impact of stroke on glial cell activation and blood brain-barrier permeability via a putative miR-124/PRX1 signalling pathway. | Extracellular vesicles from bone marrow stromal cells reduce the impact of stroke on glial cell activation and blood brain-barrier permeability via a putative miR-124/PRX1 signalling pathway.
Tian J, Yao H, Liu Y, Wang X, Wu J, Wang J, Yu D, Xie Y, Gao J, Zhu Y, Yang C. | 07/23/2022 |
| The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke. | The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke.
Kim S, Lee W, Jo H, Sonn SK, Jeong SJ, Seo S, Suh J, Jin J, Kweon HY, Kim TK, Moon SH, Jeon S, Kim JW, Kim YR, Lee EW, Shin HK, Park SH, Oh GT., Free PMC Article | 07/16/2022 |
| Post natal expression of Prx1 labels appendicular restricted progenitor cell populations of multiple tissues. | Post natal expression of Prx1 labels appendicular restricted progenitor cell populations of multiple tissues.
Bragdon BC, Bennie A, Molinelli A, Liu Y, Gerstenfeld LC., Free PMC Article | 05/28/2022 |
| PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress. | PRDX-1 Supports the Survival and Antitumor Activity of Primary and CAR-Modified NK Cells under Oxidative Stress.
Klopotowska M, Bajor M, Graczyk-Jarzynka A, Kraft A, Pilch Z, Zhylko A, Firczuk M, Baranowska I, Lazniewski M, Plewczynski D, Goral A, Soroczynska K, Domagala J, Marhelava K, Slusarczyk A, Retecki K, Ramji K, Krawczyk M, Temples MN, Sharma B, Lachota M, Netskar H, Malmberg KJ, Zagozdzon R, Winiarska M., Free PMC Article | 05/7/2022 |
| Peroxiredoxin-I Sustains Inflammation During Pancreatitis. | Peroxiredoxin-I Sustains Inflammation During Pancreatitis.
Buckens H, Pirenne S, Achouri Y, Baldan J, Dahou H, Bouwens L, Lemaigre FP, Jacquemin P, Assi M., Free PMC Article | 01/29/2022 |
| Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy. | Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy.
Zhang Z, Ji Z, He J, Lu Y, Tian W, Zheng C, Chen H, Zhang Q, Yang F, Zhang M, Yin Y, Jiang R, Chu WM, Zhang W, Sun B. | 01/15/2022 |
| Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins. | Nicotine promotes the development of oral leukoplakia via regulating peroxiredoxin 1 and its binding proteins.
Qi M, Li L, Tang X, Lu Y, Wang M, Yang J, Zhang M., Free PMC Article | 06/12/2021 |
| Peroxiredoxin I deficiency increases pancreatic betacell apoptosis after streptozotocin stimulation via the AKT/GSK3beta signaling pathway. | Peroxiredoxin I deficiency increases pancreatic β‑cell apoptosis after streptozotocin stimulation via the AKT/GSK3β signaling pathway.
Jin MH, Shen GN, Jin YH, Sun HN, Zhen X, Zhang YQ, Lee DS, Cui YD, Yu LY, Kim JS, Kwon T, Han YH., Free PMC Article | 04/24/2021 |
| Peroxiredoxin-1 ameliorates pressure overload-induced cardiac hypertrophy and fibrosis. | Peroxiredoxin-1 ameliorates pressure overload-induced cardiac hypertrophy and fibrosis.
Tang C, Yin G, Huang C, Wang H, Gao J, Luo J, Zhang Z, Wang J, Hong J, Chai X. | 02/27/2021 |
| Peroxiredoxin-1 aggravates lipopolysaccharide-induced septic shock via promoting inflammation. | Peroxiredoxin-1 aggravates lipopolysaccharide-induced septic shock via promoting inflammation.
He Y, Peng Y, Tao L, Peng Z, Yang H. | 01/16/2021 |
| Ablation of Tsc1 in kidney stromal cells causes cysts from loop of Henle, which is different from the cysts caused by ablation of Tsc1 in Osterix-labeled tubular cells in morphology and origin. | Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse.
Wu Z, Wu H, Md S, Yu G, Habib SL, Li B, Li J., Free PMC Article | 08/12/2020 |
| Data indicate that eroxiredoxin 1 (PRDX1) contributed to cerebral stroke by interacting with toll-like receptor-4 (TLR4), providing an effective therapeutic approach for cerebral ischemia-reperfusion injury (I-R injury). | PRDX1 enhances cerebral ischemia-reperfusion injury through activation of TLR4-regulated inflammation and apoptosis.
Liu Q, Zhang Y. | 06/27/2020 |
| this study provides the first demonstration for serum Prdx1 contributing to acute liver injury | Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation.
He Y, Li S, Tang D, Peng Y, Meng J, Peng S, Deng Z, Qiu S, Liao X, Chen H, Tu S, Tao L, Peng Z, Yang H. | 06/13/2020 |
| In this study we have used the mouse RAW 264.7 macrophage and the human THP-1 monocyte cell line to investigate the pattern of expression of three Nrf2 target genes, PRDX1, TXN reductase (TXNRD1) and heme oxygenase (HMOX1), by activation of different Toll-like receptors (TLRs) | Differential induction of nuclear factor-like 2 signature genes with toll-like receptor stimulation.
Ingram S, Mengozzi M, Sacre S, Mullen L, Ghezzi P. | 05/23/2020 |
| These data suggest that PRDX1 repressed the activated phenotype of fibroblasts in part through JNK inhibition which may present a novel therapeutic option for cancer-associated fibroblasts-enriched cancers such as breast cancer. | The peroxidase PRDX1 inhibits the activated phenotype in mammary fibroblasts through regulating c-Jun N-terminal kinases.
Jezierska-Drutel A, Attaran S, Hopkins BL, Skoko JJ, Rosenzweig SA, Neumann CA., Free PMC Article | 02/29/2020 |