Erbin alleviates sepsis-induced cardiomyopathy by inhibiting RIPK1-dependent necroptosis through activating PKA/CREB pathway.
Zhou H, Gong H, Liu H, Jing G, Xia Y, Wang Y, Wu D, Yang C, Zuo J, Wang Y, Wu X, Song X.

Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection.
Jetton D, Muendlein HI, Connolly WM, Magri Z, Smirnova I, Batorsky R, Mecsas J, Degterev A, Poltorak A., Free PMC Article

ASIC1/RIP1 accelerates atherosclerosis via disrupting lipophagy.
Wang YM, Tang H, Tang YJ, Liu J, Yin YF, Tang YL, Feng YG, Gu HF., Free PMC Article

RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia.
Veli Ö, Kaya Ö, Varanda AB, Hildebrandt X, Xiao P, Estornes Y, Poggenberg M, Wang Y, Pasparakis M, Bertrand MJM, Walczak H, Annibaldi A, Cardozo AK, Peltzer N., Free PMC Article

Sirt1 Deficiency Promotes Age-Related AF Through Enhancing Atrial Necroptosis by Activation of RIPK1 Acetylation.
Jin X, Zhang Y, Zhou Y, Luo Y, Han X, Gao Y, Yu H, Duan Y, Shi L, Wu Y, Li Y.

A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death.
Mannion J, Gifford V, Bellenie B, Fernando W, Ramos Garcia L, Wilson R, John SW, Udainiya S, Patin EC, Tiu C, Smith A, Goicoechea M, Craxton A, Moraes de Vasconcelos N, Guppy N, Cheung KJ, Cundy NJ, Pierrat O, Brennan A, Roumeliotis TI, Benstead-Hume G, Alexander J, Muirhead G, Layzell S, Lyu W, Roulstone V, Allen M, Baldock H, Legrand A, Gabel F, Serrano-Aparicio N, Starling C, Guo H, Upton J, Gyrd-Hansen M, MacFarlane M, Seddon B, Raynaud F, Roxanis I, Harrington K, Haider S, Choudhary JS, Hoelder S, Tenev T, Meier P.,

RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis.
Huysentruyt J, Steels W, Ruiz Perez M, Verstraeten B, Vadi M, Divert T, Flies K, Takahashi N, Lambrecht BN, Declercq W, Vanden Berghe T, Maelfait J, Vandenabeele P, Tougaard P., Free PMC Article

RIP1 kinase inactivation protects against LPS-induced acute respiratory distress syndrome in mice.
Mago E, Zhao X, Zhang W, Shao Q, Li P, Huang S, Ding X, Liu H, Sun T, He F, Weng D.

Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice.
Camps G, Maestro S, Torella L, Herrero D, Usai C, Bilbao-Arribas M, Aldaz A, Olagüe C, Vales A, Suárez-Amarán L, Aldabe R, Gonzalez-Aseguinolaza G., Free PMC Article

Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1.
Yang Y, Zhang J, Lv M, Cui N, Shan B, Sun Q, Yan L, Zhang M, Zou C, Yuan J, Xu D.

PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.
Hou S, Zhang J, Jiang X, Yang Y, Shan B, Zhang M, Liu C, Yuan J, Xu D.

Binding of RAGE and RIPK1 induces cognitive deficits in chronic hyperglycemia-derived neuroinflammation.
Zhou X, Zhu Y, Gao L, Li Y, Li H, Huang C, Liu Y, Hu A, Ying C, Song Y., Free PMC Article

Inhibiting RIPK1-driven neuroinflammation and neuronal apoptosis mitigates brain injury following experimental subarachnoid hemorrhage.
Wu Y, Xu Y, Sun J, Dai K, Wang Z, Zhang J.

RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT.
Cao Z, Min X, Xie X, Huang M, Liu Y, Sun W, Xu G, He M, He K, Li Y, Yuan J., Free PMC Article

The role and mechanism of RIPK1 in vascular endothelial dysfunction in chronic kidney disease.
Wang C, Chen H, Su H, Sheng Q, Lang Y, Yu Q, Lv Z, Wang R.

RIPK1 plays a crucial role in maintaining regulatory T-Cell homeostasis by inhibiting both RIPK3- and FADD-mediated cell death.
Deng X, Wang L, Zhai Y, Liu Q, Du F, Zhang Y, Zhao W, Wu T, Tao Y, Deng J, Cao Y, Hao P, Ren J, Shen Y, Yu Z, Zheng Y, Zhang H, Wang H.,

IKKε and TBK1 prevent RIPK1 dependent and independent inflammation.
Eren RO, Kaya GG, Schwarzer R, Pasparakis M., Free PMC Article

Excessive apoptosis of Rip1-deficient T cells leads to premature aging.
Wang L, Zhang X, Zhang H, Lu K, Li M, Li X, Ou Y, Zhao X, Wu X, Wu X, Liu J, Xing M, Liu H, Zhang Y, Tan Y, Li F, Deng X, Deng J, Zhang X, Li J, Zhao Y, Ding Q, Wang H, Wang X, Luo Y, Zhou B, Zhang H., Free PMC Article

Inhibitor of nuclear factor kappa B kinase subunit epsilon regulates murine acetaminophen toxicity via RIPK1/JNK.
Xu Y, Xu H, Ling T, Cui Y, Zhang J, Mu X, Zhou D, Zhao T, Li Y, Su Z, You Q.

Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation.
Lin Y, Sheng M, Qin H, Zhang P, Wang C, Fu W, Meng X, Wang D, Hou Y., Free PMC Article

RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development.
Hägglöf T, Parthasarathy R, Liendo N, Dudley EA, Leadbetter EA., Free PMC Article

Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases.
Xinyu W, Qian W, Yanjun W, Jingwen K, Keying X, Jiazheng J, Haibing Z, Kai W, Xiao X, Lixing Z., Free PMC Article

A novel RIP1-mediated canonical WNT signaling pathway that promotes colorectal cancer metastasis via β -catenin stabilization-induced EMT.
Kang AR, Kim JL, Kim Y, Kang S, Oh SC, Park JK., Free PMC Article

Immune regulator IRF1 contributes to ZBP1-, AIM2-, RIPK1-, and NLRP12-PANoptosome activation and inflammatory cell death (PANoptosis).
Sharma BR, Karki R, Rajesh Y, Kanneganti TD., Free PMC Article

PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.
Wang YK, Ma N, Xu S, Huang JY, Ni QZ, Cao HJ, Zheng QW, Zhu B, Xia J, Zhang FK, Ding XF, Qiu XS, Chen TW, Wang K, Chen W, Li ZG, Cheng SQ, Xie D, Li JJ.