| Correlation of FBXO45 Expression Levels with Cancer Severity by ZEB1 Ubiquitin in Non-Small-Cell Lung Cancer. | Correlation of FBXO45 Expression Levels with Cancer Severity by ZEB1 Ubiquitin in Non-Small-Cell Lung Cancer.
Zhang F, Wang Y, He Y, Dong B. | 08/5/2024 |
| LncRNA MEG8 ameliorates Parkinson's disease neuro-inflammation through miR-485-3p/FBXO45 axis. | LncRNA MEG8 ameliorates Parkinson's disease neuro-inflammation through miR-485-3p/FBXO45 axis.
Lin X, Tao T, He X, Mao L, Pan L, Chen L. | 03/29/2024 |
| Fbxo45-mediated NP-STEP46 degradation via K6-linked ubiquitination sustains ERK activity in lung cancer. | Fbxo45-mediated NP-STEP(46) degradation via K6-linked ubiquitination sustains ERK activity in lung cancer.
Wang Q, Xu C, Cai R, An W, Yuan H, Xu M., Free PMC Article | 08/27/2022 |
| MiR-30a-5p hampers proliferation of lung squamous cell carcinoma through targeting FBXO45. | MiR-30a-5p hampers proliferation of lung squamous cell carcinoma through targeting FBXO45.
Zeng F, You S, Dai X. | 07/2/2022 |
| Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation. | Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.
Wu L, Yu K, Chen K, Zhu X, Yang Z, Wang Q, Gao J, Wang Y, Cao T, Xu H, Pan X, Wang L, Xia J, Li Y, Wang ZP, Ma J., Free PMC Article | 04/16/2022 |
| Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation. | Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.
Lin XT, Yu HQ, Fang L, Tan Y, Liu ZY, Wu D, Zhang J, Xiong HJ, Xie CM., Free PMC Article | 12/18/2021 |
| DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1. | DNAJB9 suppresses the metastasis of triple-negative breast cancer by promoting FBXO45-mediated degradation of ZEB1.
Kim HY, Kim YM, Hong S., Free PMC Article | 10/16/2021 |
| FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation. | FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.
Richter KT, Kschonsak YT, Vodicska B, Hoffmann I., Free PMC Article | 07/3/2021 |
| A SNP at the rs6583331 locus 3q29 is associated with the susceptibility of vitiligo in the Chinese Han population. The T allele of the locus within the FBXO45-NRROS gene (3q29) was significantly associated with vitiligo (odds ratio = 1.22, 95% confidence interval: 1.10-1.36, p = 0.0001). Association at the genotype level was strong (p = 0.0007). | Association Study Reveals One Susceptibility Locus with Vitiligo in the Chinese Han Population.
Tang X, Fang F, Yang J, Zheng X, Fan M, Wang L, Zhang A. | 03/21/2020 |
| Genetic variations in FBXO45 are associated with emotional expression. | A genome-wide association study of coping behaviors suggests FBXO45 is associated with emotional expression.
Shimanoe C, Hachiya T, Hara M, Nishida Y, Tanaka K, Sutoh Y, Shimizu A, Hishida A, Kawai S, Okada R, Tamura T, Matsuo K, Ito H, Ozaki E, Matsui D, Ibusuki R, Shimoshikiryo I, Takashima N, Kadota A, Arisawa K, Uemura H, Suzuki S, Watanabe M, Kuriki K, Endoh K, Mikami H, Nakamura Y, Momozawa Y, Kubo M, Nakatochi M, Naito M, Wakai K. | 03/23/2019 |
| FBXO45 does not simply function in substrate recognition but is important for assembly of the PAM/FBXO45/SKP1 complex. | PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2.
Desbois M, Crawley O, Evans PR, Baker ST, Masuho I, Yasuda R, Grill B., Free PMC Article | 03/2/2019 |
| Relatively low FBXO45 expression in gastric cancer tissues is associated with cancer progression and constitutes an independent prognostic factor | Low Expression of FBXO45 Is Associated with Gastric Cancer Progression and Poor Prognosis.
Kogure N, Yokobori T, Ogata K, Altan B, Mochiki E, Ohno T, Toyomasu Y, Yanai M, Kimura A, Yanoma T, Suzuki M, Bai T, Asao T, Kuwano H. | 01/28/2017 |
| Data show that epithelial-mesenchymal transition (EMT)-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 (SPFFbxo45). | Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.
Xu M, Zhu C, Zhao X, Chen C, Zhang H, Yuan H, Deng R, Dou J, Wang Y, Huang J, Chen Q, Jiang B, Yu J., Free PMC Article | 11/28/2015 |
| Fbxo45 is the substrate-receptor subunit of a functional E3 ligase for Par-4 that has a critical role in cancer cell survival. | Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival.
Chen X, Sahasrabuddhe AA, Szankasi P, Chung F, Basrur V, Rangnekar VM, Pagano M, Lim MS, Elenitoba-Johnson KS., Free PMC Article | 06/20/2015 |
| Study found that the R108C mutation in FBXO45 is a rare variant with a modest effect on schizophrenia risk that may disrupt the structure and function of the FBXO45 protein | Novel rare variants in F-box protein 45 (FBXO45) in schizophrenia.
Wang C, Koide T, Kimura H, Kunimoto S, Yoshimi A, Nakamura Y, Kushima I, Banno M, Kawano N, Takasaki Y, Xing J, Noda Y, Mouri A, Aleksic B, Ikeda M, Okada T, Iidaka T, Inada T, Iwata N, Ozaki N. | 02/28/2015 |
| FBXO45 promotes the proteasome-dependent degradation of p73. | The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.
Peschiaroli A, Scialpi F, Bernassola F, Pagano M, Melino G., Free PMC Article | 01/21/2010 |
| FBXO45 gene consisting of 3 exons, and the vicinity of the transcriptional start site had several estrogen receptor binding consensus sequences. | Characterization of estrogen-induced F-box protein FBXO45.
Yoshida K. | 01/21/2010 |