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    ENO2 enolase 2 [ Homo sapiens (human) ]

    Gene ID: 2026, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circular RNA circESYT2 serves as a microRNA-665 sponge to promote the progression of hepatocellular carcinoma through ENO2.

    Circular RNA circESYT2 serves as a microRNA-665 sponge to promote the progression of hepatocellular carcinoma through ENO2.
    Du W, Li Y, Wang X, Xie S, Ci H, Zhou J, Zhu N, Chen Z, Zheng Y, Jia H., Free PMC Article

    09/18/2024
    gamma-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells.

    γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells.
    Pišlar A, Kos J., Free PMC Article

    08/27/2024
    HOXC6-mediated transcriptional activation of ENO2 promotes oral squamous cell carcinoma progression through the Warburg effect.

    HOXC6-mediated transcriptional activation of ENO2 promotes oral squamous cell carcinoma progression through the Warburg effect.
    Feng J, Fang J.

    07/22/2024
    Lactic acid, neuron-specific enolase, and blood-brain barrier index after a severe traumatic brain injury: a prospective study.

    Lactic acid, neuron-specific enolase, and blood-brain barrier index after a severe traumatic brain injury: a prospective study.
    Lu W, Jiang C, Wang Z, Chen Y, Bai R, Yan G, Wang G, Ren H.

    03/25/2024
    Tumor-derived Exosomal ENO2 Modulates Polarization of Tumor-associated Macrophages through Reprogramming Glycolysis to Promote Progression of Diffuse Large B-cell Lymphoma.

    Tumor-derived Exosomal ENO2 Modulates Polarization of Tumor-associated Macrophages through Reprogramming Glycolysis to Promote Progression of Diffuse Large B-cell Lymphoma.
    Shao R, Liu C, Xue R, Deng X, Liu L, Song C, Xie J, Tang H, Liu W., Free PMC Article

    02/16/2024
    Neuron-specific enolase at admission as a predictor for stroke volume, severity and outcome in ischemic stroke patients: a prognostic biomarker review.

    Neuron-specific enolase at admission as a predictor for stroke volume, severity and outcome in ischemic stroke patients: a prognostic biomarker review.
    Mochetti MM, Silva EGP, Correa AAF, Cabette MR, Perissinotti IN, E Silva LOJ, Pessoa AS, de Oliveira RC, da Silva LFF, de Souza HP, de Alencar JCG., Free PMC Article

    02/12/2024
    Evaluating the diagnostic and prognostic value of serum TuM2-PK, NSE, and ProGRP in small cell lung cancer.

    Evaluating the diagnostic and prognostic value of serum TuM2-PK, NSE, and ProGRP in small cell lung cancer.
    Li L, Zhang Q, Wang Y, Xu C., Free PMC Article

    06/1/2023
    Neuron-specific enolase in hypertension patients with acute ischemic stroke and its value forecasting long-term functional outcomes.

    Neuron-specific enolase in hypertension patients with acute ischemic stroke and its value forecasting long-term functional outcomes.
    Gao L, Xie J, Zhang H, Zheng H, Zheng W, Pang C, Cai Y, Deng B., Free PMC Article

    05/22/2023
    MRI changes and expressions of neuron-specific enolase and monocyte chemoattractant protein-1 in cerebrospinal fluid in patients with severe herpes simplex virus encephalitis.

    MRI changes and expressions of neuron-specific enolase and monocyte chemoattractant protein-1 in cerebrospinal fluid in patients with severe herpes simplex virus encephalitis.
    Yao Y, Gu J, Li M, Li G, Zhao L, Ai J.

    05/3/2023
    Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness.

    Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness.
    Andreou D, Steen NE, Jørgensen KN, Smelror RE, Wedervang-Resell K, Nerland S, Westlye LT, Nærland T, Myhre AM, Joa I, Reitan SMK, Vaaler A, Morken G, Bøen E, Elvsåshagen T, Boye B, Malt UF, Aukrust P, Skrede S, Kroken RA, Johnsen E, Djurovic S, Andreassen OA, Ueland T, Agartz I., Free PMC Article

    04/4/2023
    ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis.

    ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis.
    De Vitis C, Battaglia AM, Pallocca M, Santamaria G, Mimmi MC, Sacco A, De Nicola F, Gaspari M, Salvati V, Ascenzi F, Bruschini S, Esposito A, Ricci G, Sperandio E, Massacci A, Prestagiacomo LE, Vecchione A, Ricci A, Sciacchitano S, Salerno G, French D, Aversa I, Cereda C, Fanciulli M, Chiaradonna F, Solito E, Cuda G, Costanzo F, Ciliberto G, Mancini R, Biamonte F., Free PMC Article

    03/29/2023
    CSF neuron-specific enolase as a biomarker of neurovascular conflict severity in drug-resistant trigeminal neuralgia: a prospective study in patients submitted to microvascular decompression.

    CSF neuron-specific enolase as a biomarker of neurovascular conflict severity in drug-resistant trigeminal neuralgia: a prospective study in patients submitted to microvascular decompression.
    Baroni S, Rapisarda A, Gentili V, Burattini B, Moretti G, Sarlo F, Izzo A, D'Ercole M, Olivi A, Urbani A, Montano N.

    03/22/2023
    ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune microenvironment.

    ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune microenvironment.
    Chen WJ, Yang W, Gong M, He Y, Xu D, Chen JX, Chen WJ, Li WY, Wang YQ, Dong KQ, Song X, Pan XW, Cui XG., Free PMC Article

    01/14/2023
    Integrated Analysis of the Role of Enolase 2 in Clear Cell Renal Cell Carcinoma.

    Integrated Analysis of the Role of Enolase 2 in Clear Cell Renal Cell Carcinoma.
    Pan J, Jin Y, Xu X, Wei W, Pan H., Free PMC Article

    12/3/2022
    Two Useful Umbilical Biomarkers for Therapeutic Hypothermia Decision in Patients with Hypoxic Ischemic Encephalopathy with Perinatal Asphyxia: Netrin-1 and Neuron Specific Enolase.

    Two Useful Umbilical Biomarkers for Therapeutic Hypothermia Decision in Patients with Hypoxic İschemic Encephalopathy with Perinatal Asphyxia: Netrin-1 and Neuron Specific Enolase.
    Cakir U, Ceran B, Tayman C.

    11/5/2022
    The Value of the Biomarkers Neuron-Specific Enolase and S100 Calcium-Binding Protein for Prediction of Mortality in Children Resuscitated After Cardiac Arrest.

    The Value of the Biomarkers Neuron-Specific Enolase and S100 Calcium-Binding Protein for Prediction of Mortality in Children Resuscitated After Cardiac Arrest.
    Bangshøj J, Liebetrau B, Wiberg S, Gjedsted J, Kjærgaard J, Hassager C, Wanscher M., Free PMC Article

    10/15/2022
    ENO2 Promotes Colorectal Cancer Metastasis by Interacting with the LncRNA CYTOR and Activating YAP1-Induced EMT.

    ENO2 Promotes Colorectal Cancer Metastasis by Interacting with the LncRNA CYTOR and Activating YAP1-Induced EMT.
    Lv C, Yu H, Wang K, Chen C, Tang J, Han F, Mai M, Ye K, Lai M, Zhang H., Free PMC Article

    08/20/2022
    Brain damage markers neuron-specific enolase (NSE) and S100B in serum in children with Lyme neuroborreliosis-detection and evaluation as prognostic biomarkers for clinical outcome.

    Brain damage markers neuron-specific enolase (NSE) and S100B in serum in children with Lyme neuroborreliosis-detection and evaluation as prognostic biomarkers for clinical outcome.
    Arnason S, Molewijk K, Henningsson AJ, Tjernberg I, Skogman BH., Free PMC Article

    07/23/2022
    Neuron Specific Enolase, S100-beta protein and progranulin as diagnostic biomarkers of status epilepticus.

    Neuron Specific Enolase, S100-beta protein and progranulin as diagnostic biomarkers of status epilepticus.
    Hanin A, Denis JA, Frazzini V, Cousyn L, Imbert-Bismut F, Rucheton B, Bonnefont-Rousselot D, Marois C, Lambrecq V, Demeret S, Navarro V.

    07/2/2022
    Clinical Value of Serum Neuron-Specific Enolase Combined with Serum S100B Protein in the Diagnosis of Systemic Lupus Erythematosus.

    Clinical Value of Serum Neuron-Specific Enolase Combined with Serum S100B Protein in the Diagnosis of Systemic Lupus Erythematosus.
    Chen J, Yan Cheng, Zhang X, Wang F, Chuai X., Free PMC Article

    06/18/2022
    E2F1 promotes Warburg effect and cancer progression via upregulating ENO2 expression in Ewing sarcoma.

    E2F1 promotes Warburg effect and cancer progression via upregulating ENO2 expression in Ewing sarcoma.
    Jiang X, Chen Z, Zhu J, Han J, You G, Li Y, Liu T, Ye H., Free PMC Article

    06/11/2022
    NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.

    NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
    Lu L, Zha Z, Zhang P, Li D, Liu G., Free PMC Article

    03/12/2022
    Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients.

    Plasma Neuron-Specific Enolase is not a reliable biomarker for staging Trypanosoma brucei rhodesiense sleeping sickness patients.
    Kato CD, Twesigye D, Alibu VP, Nanteza A, Nsubuga J, Mugasa CM, Matovu E., Free PMC Article

    03/12/2022
    Overexpression of let-7d explains down-regulated KDM3A and ENO2 in the pathogenesis of preeclampsia.

    Overexpression of let-7d explains down-regulated KDM3A and ENO2 in the pathogenesis of preeclampsia.
    Xu Q, Song Y, Lu L., Free PMC Article

    02/19/2022
    Neuron-specific enolase level is a useful biomarker for distinguishing amyotrophic lateral sclerosis from cervical spondylotic myelopathy.

    Neuron-specific enolase level is a useful biomarker for distinguishing amyotrophic lateral sclerosis from cervical spondylotic myelopathy.
    Tsukahara A, Hosokawa T, Nishioka D, Kotani T, Ishida S, Takeuchi T, Kimura F, Arawaka S., Free PMC Article

    02/5/2022
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