| Piezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway. | Piezo1 activation on microglial cells exacerbates demyelination in sepsis by influencing the CCL25/GRP78 pathway.
Xie D, Ma Y, Gao C, Pan S. | 10/17/2024 |
| ZIM3 activation of CCL25 expression in pulmonary metastatic nodules of osteosarcoma recruits M2 macrophages to promote metastatic growth. | ZIM3 activation of CCL25 expression in pulmonary metastatic nodules of osteosarcoma recruits M2 macrophages to promote metastatic growth.
Li J, Zhao C, Wang D, Wang S, Dong H, Wang D, Yang Y, Li J, Cui F, He X, Qin J., Free PMC Article | 03/23/2023 |
| The murine DCs transfected with DNA-plasmid encoding CCR9 demonstrate the increased migration to CCL25 and thymic cells in vitro and to the thymus in vivo. | The murine DCs transfected with DNA-plasmid encoding CCR9 demonstrate the increased migration to CCL25 and thymic cells in vitro and to the thymus in vivo.
Tereshchenko V, Bulygin A, Zavodskii R, Maksyutov A, Kurilin V, Fisher M, Semenyuk N, Aladev S, Sennikov S. | 01/22/2022 |
| Impaired CCR9/CCL25 signalling induced by inefficient dendritic cells contributes to intestinal immune imbalance in nonalcoholic steatohepatitis. | Impaired CCR9/CCL25 signalling induced by inefficient dendritic cells contributes to intestinal immune imbalance in nonalcoholic steatohepatitis.
Gao W, Wang Y, Bi J, Chen X, Li N, Wang Y, Tang H, Mao J. | 04/17/2021 |
| Toll-Like Receptor 4 Promotes Th17 Lymphocyte Infiltration Via CCL25/CCR9 in Pathogenesis of Experimental Autoimmune Encephalomyelitis. | Toll-Like Receptor 4 Promotes Th17 Lymphocyte Infiltration Via CCL25/CCR9 in Pathogenesis of Experimental Autoimmune Encephalomyelitis.
Zhang Y, Han J, Wu M, Xu L, Wang Y, Yuan W, Hua F, Fan H, Dong F, Qu X, Yao R. | 09/19/2020 |
| these results showed a site- and cell-specific expressions of Ccl25 and its receptor Ccr9 within both maternal and embryonic compartments of implantation sites and suggested a role in inducing specific Ccr9+ leukocytes at the maternal-fetal interface during the initial steps of embryo implantation in the mouse model | Chemokine (C-C motif) ligand 25 expressed by trophoblast cells and leukocytes bearing its receptor Ccr9: An alliance during embryo implantation?
Weingrill RB, Hoshida MS, Martinhago CD, Correa-Silva S, Cardoso E, Palmeira P, Marinho CRF, Bevilacqua E. | 07/14/2018 |
| MicroRNA-205 maintains T cell development following stress by regulating Foxn1 and its two regulated targets, stem cell factor and ccl25, following stress. | MicroRNA-205 Maintains T Cell Development following Stress by Regulating Forkhead Box N1 and Selected Chemokines.
Hoover AR, Dozmorov I, MacLeod J, Du Q, de la Morena MT, Forbess J, Guleserian K, Cleaver OB, van Oers NS., Free PMC Article | 09/30/2017 |
| CCR9 and CCL25 expressions are induced in the early stages of airway inflammation and they have an important role modulating eosinophils and lymphocytes recruitment at the first stages of inflammatory process | CCR9 Is a Key Regulator of Early Phases of Allergic Airway Inflammation.
López-Pacheco C, Soldevila G, Du Pont G, Hernández-Pando R, García-Zepeda EA., Free PMC Article | 08/12/2017 |
| TECK was shown to be expressed by osteoblasts, and its receptor, CCR9, by osteoclast precursors. TECK increased P. gingivalis LPS-induced osteoclast numbers in an in vitro osteoclast formation assay using osteoclast precursors. T | Thymus-expressed chemokine enhances Porphyromonas gingivalis LPS-induced osteoclast formation via NFATc1 activation.
Usui M, Okamatsu Y, Sato T, Hanatani T, Moritani Y, Sano K, Yamamoto M, Nakashima K. | 02/18/2017 |
| CCR9/CCL25 is involved in acute skin transplantation rejection and anti-CCL25 strategies might be useful in preventing acute rejection. | Anti-CCL25 antibody prolongs skin allograft survival by blocking CCR9 expression and impairing splenic T-cell function.
Li J, Xiong T, Xiao R, Xiong A, Chen J, Altaf E, Zheng Y, Zhu G, He Y, Tan J. | 10/26/2013 |
| Accumulated CD11b(+) macrophages are critical for activating hepatic stellate cells through the CCR9/CCL25 axis and therefore promote liver fibrosis. | C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.
Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito H, Hibi T. | 08/31/2013 |
| The results revealed that during an allergic reaction, CCL25 drives IL-17 gammadelta T-cell mobilization to inflamed tissue via alpha4beta7 integrin and modulates IL-17 levels. | CCL25 induces α₄β₇ integrin-dependent migration of IL-17⁺ γδ T lymphocytes during an allergic reaction.
Costa MF, Bornstein VU, Candéa AL, Henriques-Pons A, Henriques MG, Penido C. | 07/7/2012 |
| CCL25/CCR9 interactions regulate inflammatory immune responses in the large intestinal mucosa by balancing different subsets of dendritic cells. | CCL25/CCR9 interactions regulate large intestinal inflammation in a murine model of acute colitis.
Wurbel MA, McIntire MG, Dwyer P, Fiebiger E., Free PMC Article | 08/6/2011 |
| Ovarian CC chemokine thymus-expressed chemokine (TECK) appears to be a chemoattractant for CD8 alpha alpha-positive cells. | Potential roles of a special CD8 alpha alpha+ cell population and CC chemokine thymus-expressed chemokine in ovulation related inflammation.
Zhou C, Wu J, Borillo J, Torres L, McMahon J, Lou YH., Free PMC Article | 01/21/2010 |
| CCL25 increases thymopoiesis after androgen withdrawal | CCL25 increases thymopoiesis after androgen withdrawal.
Williams KM, Lucas PJ, Bare CV, Wang J, Chu YW, Tayler E, Kapoor V, Gress RE., Free PMC Article | 01/21/2010 |
| Demonstrate development of intestinal inflammation in Tnf(DeltaARE) mice is critically dependent on beta7 integrin-mediated T-lymphocyte recruitment. the function of the CCL25/CCR9 axis appears dispensable in this model. | Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.
Apostolaki M, Manoloukos M, Roulis M, Wurbel MA, Müller W, Papadakis KA, Kontoyiannis DL, Malissen B, Kollias G. | 01/21/2010 |
| Intracellular signaling required for Ccl25-stimulated T cell adhesion mediated by the integrin alpha4beta1. | Intracellular signaling required for CCL25-stimulated T cell adhesion mediated by the integrin alpha4beta1.
Parmo-Cabañas M, García-Bernal D, García-Verdugo R, Kremer L, Márquez G, Teixidó J. | 01/21/2010 |
| role of CCL25 in the generation of the small-intestinal CD8alpha alpha(+)CD3(+) intraepithelial lymphocyte compartment | Involvement of CCL25 (TECK) in the generation of the murine small-intestinal CD8alpha alpha+CD3+ intraepithelial lymphocyte compartment.
Marsal J, Svensson M, Ericsson A, Iranpour AH, Carramolino L, Márquez G, Agace WW. | 01/21/2010 |
| Epithelial cells and venular endothelium of small intestine are immunologically positive for CCL25, a chemokine which plays a direct role in intestinal homing of IgA antibody-secreting cells by mediating their extravasation into intestinal lamina propria. | CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells.
Hieshima K, Kawasaki Y, Hanamoto H, Nakayama T, Nagakubo D, Kanamaru A, Yoshie O. | 01/21/2010 |
| demonstrate a unique pattern of regulation for CCL25 and suggest a role for caudal type homeo box proteins in regulating CCL25 transcription | Functional characterization of the CCL25 promoter in small intestinal epithelial cells suggests a regulatory role for caudal-related homeobox (Cdx) transcription factors.
Ericsson A, Kotarsky K, Svensson M, Sigvardsson M, Agace W. | 01/21/2010 |
| Chemokine CCL25 enhances CD103-mediated adhesion to E-cadherin. | CCL25 enhances CD103-mediated lymphocyte adhesion to E-cadherin.
Ericsson A, Arya A, Agace W. | 01/21/2010 |
| Neonatal CD8+ splenocytes uniformly express alpha(E) integrin and exhibit a high responsiveness to CC chemokine ligand 25. With increasing age, the frequency of CD8+ alpha(E) integrin(+) splenocytes decreases, roughly correlating with thymic involution. | Murine CD8+ recent thymic emigrants are alphaE integrin-positive and CC chemokine ligand 25 responsive.
Staton TL, Johnston B, Butcher EC, Campbell DJ. | 01/21/2010 |
| chemokine (C-C motif) ligand 25 may thus play an important role in the adherence of mucosal lymphocytes to the microvessels of the small intestine but not the colon under uninflamed as well as inflamed conditions | Demonstration of functional role of TECK/CCL25 in T lymphocyte-endothelium interaction in inflamed and uninflamed intestinal mucosa.
Hosoe N, Miura S, Watanabe C, Tsuzuki Y, Hokari R, Oyama T, Fujiyama Y, Nagata H, Ishii H. | 01/21/2010 |
| in vivo neutralization of the CCR9 ligand, CCL25, reduced the ability of activated CCR9(+) CD8alphabeta(+) lymphocytes cells to populate the small-intestinal epithelium | CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.
Svensson M, Marsal J, Ericsson A, Carramolino L, Brodén T, Márquez G, Agace WW., Free PMC Article | 01/21/2010 |
| CCL25 is indispensable for CD8 T cells trafficking to the small intestine. | Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria.
Wurbel MA, Malissen M, Guy-Grand D, Malissen B, Campbell JJ., Free PMC Article | 01/21/2010 |