| Neuroplastin Expression in Male Mice Is Essential for Fertility, Mating, and Adult Testosterone Levels. | Neuroplastin Expression in Male Mice Is Essential for Fertility, Mating, and Adult Testosterone Levels.
Chen J, Lin X, Bhattacharya S, Wiesehöfer C, Wennemuth G, Müller K, Montag D., Free PMC Article | 01/16/2024 |
| The role of neuroplastin65 in macrophage against E. coli infection in mice. | The role of neuroplastin65 in macrophage against E. coli infection in mice.
Ren H, Xia X, Dai X, Dai Y. | 10/1/2022 |
| Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing. | Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.
Newton S, Kong F, Carlton AJ, Aguilar C, Parker A, Codner GF, Teboul L, Wells S, Brown SDM, Marcotti W, Bowl MR., Free PMC Article | 03/5/2022 |
| Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts. | Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.
Ilic K, Lin X, Malci A, Stojanović M, Puljko B, Rožman M, Vukelić Ž, Heffer M, Montag D, Schnaar RL, Kalanj-Bognar S, Herrera-Molina R, Mlinac-Jerkovic K., Free PMC Article | 01/29/2022 |
| The amino-terminal domain of GluA1 mediates LTP maintenance via interaction with neuroplastin-65. | The amino-terminal domain of GluA1 mediates LTP maintenance via interaction with neuroplastin-65.
Jiang CH, Wei M, Zhang C, Shi YS., Free PMC Article | 08/7/2021 |
| Np65 KO mice display display enhanced anxiety-like behavior, a reduction in some aspects of depressive-like behaviors, and increased sociability and memory. Np65 KO mice show increased neurons proliferation, reduced 5-HT level and impaired long-term potentiation in the hippocampus. | Neuroplastin 65 modulates anxiety- and depression-like behavior likely through adult hippocampal neurogenesis and central 5-HT activity.
Li H, Liu Y, Gao X, Liu L, Amuti S, Wu D, Jiang F, Huang L, Wang G, Zeng J, Ma B, Yuan Q. | 05/30/2020 |
| these results indicate that epilation induces McSCs activation through EDN3/EDNRB signaling and in turn leads to skin and hair hyperpigmentation. The findings suggest that EDN/EDNRB signaling may serve as a potential therapeutic target to promote repigmentation in hypopigmentation disorders. | Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration.
Herrera-Molina R, Mlinac-Jerkovic K, Ilic K, Stöber F, Vemula SK, Sandoval M, Milosevic NJ, Simic G, Smalla KH, Goldschmidt J, Bognar SK, Montag D., Free PMC Article | 02/23/2019 |
| findings suggest that ablation of Np65 influences gene expression, which may contribute to abnormal brain development; these results provide clues to the mechanisms underlying the altered brain functions of Np65-deficient mice | Microarray Analysis of Gene Expression Changes in Neuroplastin 65-Knockout Mice: Implications for Abnormal Cognition and Emotional Disorders.
Li H, Zeng J, Huang L, Wu D, Liu L, Liu Y, Yuan Q., Free PMC Article | 11/10/2018 |
| results establish neuroplastin and basigin as obligatory auxiliary subunits of native Plasma Membrane Calcium Atpases and key regulators of intracellular Ca2+ concentration. | Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca(2+)-ATPases and Key Regulators of Ca(2+) Clearance.
Schmidt N, Kollewe A, Constantin CE, Henrich S, Ritzau-Jost A, Bildl W, Saalbach A, Hallermann S, Kulik A, Fakler B, Schulte U. | 12/23/2017 |
| The current study shows that neuroplastin, a member of the Ig superfamily, which has previously been linked to the regulation of synaptic plasticity, is critical to maintain a stable mechanical link of outer hair cells with the tectorial membrane. | Neuroplastin Isoform Np55 Is Expressed in the Stereocilia of Outer Hair Cells and Required for Normal Outer Hair Cell Function.
Zeng WZ, Grillet N, Dewey JB, Trouillet A, Krey JF, Barr-Gillespie PG, Oghalai JS, Müller U., Free PMC Article | 08/19/2017 |
| Neuroplastins are essential for learning and memory. Retrograde amnesia after an associative learning task can be induced by ablation of the neuroplastin gene. | Genetically Induced Retrograde Amnesia of Associative Memories After Neuroplastin Ablation.
Bhattacharya S, Herrera-Molina R, Sabanov V, Ahmed T, Iscru E, Stöber F, Richter K, Fischer KD, Angenstein F, Goldschmidt J, Beesley PW, Balschun D, Smalla KH, Gundelfinger ED, Montag D. | 08/12/2017 |
| In the mammalian cochlea, the sensory inner hair cells (IHCs) encode auditory information. | Absence of Neuroplastin-65 Affects Synaptogenesis in Mouse Inner Hair Cells and Causes Profound Hearing Loss.
Carrott L, Bowl MR, Aguilar C, Johnson SL, Chessum L, West M, Morse S, Dorning J, Smart E, Hardisty-Hughes R, Ball G, Parker A, Barnard AR, MacLaren RE, Wells S, Marcotti W, Brown SD., Free PMC Article | 05/14/2016 |
| Np65 is an important regulator of the number and function of synapses in the hippocampus | Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65.
Herrera-Molina R, Sarto-Jackson I, Montenegro-Venegas C, Heine M, Smalla KH, Seidenbecher CI, Beesley PW, Gundelfinger ED, Montag D., Free PMC Article | 05/24/2014 |
| We report changes in neuroplastin gene and protein expression in the hippocampus of B4galnt1 null mice, which lacks complex ganglioside structures. | Neuroplastin expression in the hippocampus of mice lacking complex gangliosides.
Mlinac K, Jovanov Milošević N, Heffer M, Smalla KH, Schnaar RL, Kalanj Bognar S. | 01/12/2013 |