The role of serum/glucocorticoid-regulated kinase 1 in brain function following cerebral ischemia.
Wu CY, Zhang Y, Xu L, Huang Z, Zou P, Clemons GA, Li C, Citadin CT, Zhang Q, Lee RH.,

Integrating analysis of mRNA expression profiles indicates Sgk1 as a key mediator in muscle-brain crosstalk during resistance exercise.
Liu Y, Ye Q, Dai Y, Hu J, Chen J, Dong J, Li H, Dou Z.

Endothelial cell serum and glucocorticoid regulated kinase 1 (SGK1) mediates vascular stiffening.
Zhang L, Sun Z, Yang Y, Mack A, Rodgers M, Aroor A, Jia G, Sowers JR, Hill MA.

SGLT2 knockdown restores the Th17/Treg balance and suppresses diabetic nephropathy in db/db mice by regulating SGK1 via Na().
Wang D, Zhang Q, Dong W, Ren S, Wang X, Su C, Lin X, Zheng Z, Xue Y.

SGK1 aggravates idiopathic pulmonary fibrosis by triggering H3k27ac-mediated macrophage reprogramming and disturbing immune homeostasis.
Wu J, Gong L, Li Y, Liu T, Sun R, Jia K, Liu R, Dong F, Gu X, Li X., Free PMC Article

SGK1 is involved in doxorubicin-induced chronic cardiotoxicity and dysfunction through activation of the NFκB pathway.
Zhang Y, Zhang D, Meng T, Tian P, Chen J, Liu A, Zheng Y, Su G.

Renal tubular SGK1 is required to achieve blood pressure surge and circadian rhythm.
Staub O, Debonneville A, Stifanelli M, Juffre A, Maillard MP, Gumz ML, Al-Qusairi L., Free PMC Article

Association between SGK1 and α-synuclein in skeletal muscle in an MPTP-induced Parkinson's disease model.
Heo EJ, Lee Y, Hyung Seo M, Yeo S.

Inflammasome activation and metabolic remodelling in p16-positive aging cells aggravates high-fat diet-induced lung fibrosis by inhibiting NEDD4L-mediated K48-polyubiquitin-dependent degradation of SGK1.
Gu X, Meng H, Peng C, Lin S, Li B, Zhao L, Yang X, Wang G, Cai W, Zhou J, Liu S, Wu P, Du Y, Jin J, Wang X., Free PMC Article

Cutting Edge: mTORC2 Regulates CD8+ Effector and Memory T Cell Differentiation through Serum and Glucocorticoid Kinase 1.
Patel CH, Heikamp EB, Xu W, Sun IH, Oh MH, Sun IM, Wen J, Tam AJ, Blosser RL, Powell JD., Free PMC Article

Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3.
Li X, Wang Z, Jiao C, Zhang Y, Xia N, Yu W, Chen X, Wikana LP, Liu Y, Sun L, Chen M, Xiao Y, Shi Y, Han S, Pu L., Free PMC Article

Transcriptomic Profile Identifies Hippocampal Sgk1 as the Key Mediator of Ovarian Estrogenic Regulation on Spatial Learning and Memory and Aβ Accumulation.
Liu M, Lian B, Lan Z, Sun H, Zhao Y, Sun T, Meng Z, Zhao C, Zhang J.

SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity.
Han X, Ren J, Lohner H, Yakoumatos L, Liang R, Wang H., Free PMC Article

SGK1 is essential for meiotic resumption in mammalian oocytes.
Del Llano E, Iyyappan R, Aleshkina D, Masek T, Dvoran M, Jiang Z, Pospisek M, Kubelka M, Susor A., Free PMC Article

Serum/glucocorticoid-regulated kinase 1-targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activated T cell nuclear factor transcription factor 2.
He J, Yang J, Chen L, He P, Liu X, Wang K, Dong T, Li J, Ma X, Bastian A, Arnulf S., Free PMC Article

Columbianetin alleviates lipopolysaccharides (LPS)-induced inflammation and apoptosis in chondrocyte through activation of autophagy by inhibiting serum and glucocorticoid-induced protein kinase 1 (SGK1) expression.
Chen W, Zheng H, Zhang X, Xu Y, Fu Z, Ji X, Wei C, An G, Tan M, Zhou M., Free PMC Article

High-fat diet-induced activation of SGK1 promotes Alzheimer's disease-associated tau pathology.
Elahi M, Motoi Y, Shimonaka S, Ishida Y, Hioki H, Takanashi M, Ishiguro K, Imai Y, Hattori N., Free PMC Article

Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy.
Zhang S, Wang Y, Yu M, Shang Y, Chang Y, Zhao H, Kang Y, Zhao L, Xu L, Zhao X, Difrancesco D, Baruscotti M, Wang Y., Free PMC Article

Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase.
Zhou B, Zhang Y, Li S, Wu L, Fejes-Toth G, Naray-Fejes-Toth A, Soukas AA., Free PMC Article

SGK1.1 limits brain damage after status epilepticus through M current-dependent and independent mechanisms.
Martin-Batista E, Maglio LE, Armas-Capote N, Hernández G, Alvarez de la Rosa D, Giraldez T.

Serum- and Glucocorticoid-Inducible Kinase 1 Promotes Alternative Macrophage Polarization and Restrains Inflammation through FoxO1 and STAT3 Signaling.
Ren J, Han X, Lohner H, Liang R, Liang S, Wang H., Free PMC Article

SGK1.1 Reduces Kainic Acid-Induced Seizure Severity and Leads to Rapid Termination of Seizures.
Armas-Capote N, Maglio LE, Pérez-Atencio L, Martin-Batista E, Reboreda A, Barios JA, Hernandez G, Alvarez de la Rosa D, Lamas JA, Barrio LC, Giraldez T.

ETS-dependent enhancers for endothelial-specific expression of serum/glucocorticoid-regulated kinase 1 during mouse embryo development.
Harada Y, Tanaka T, Arai Y, Isomoto Y, Nakano A, Nakao S, Urasaki A, Watanabe Y, Kawamura T, Nakagawa O.

SGK1 enhances Th9 cell differentiation and airway inflammation through NF-κB signaling pathway in asthma.
Wu X, Jiang W, Wang X, Zhang C, Cai J, Yu S, Sun J, Tian Z.

Hippocampal overexpression of SGK1 ameliorates spatial memory, rescues Aβ pathology and actin cytoskeleton polymerization in middle-aged APP/PS1 mice.
Lian B, Liu M, Lan Z, Sun T, Meng Z, Chang Q, Liu Z, Zhang J, Zhao C.