| Rhodopsin mislocalization drives ciliary dysregulation in a novel autosomal dominant retinitis pigmentosa knock-in mouse model. | Rhodopsin mislocalization drives ciliary dysregulation in a novel autosomal dominant retinitis pigmentosa knock-in mouse model.
Takita S, Jahan S, S Imanishi S, Harikrishnan H, LePage D, Mann RJ, Conlon RA, Miyagi M, Imanishi Y., | 05/7/2024 |
| Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors. | Light regulation of rhodopsin distribution during outer segment renewal in murine rod photoreceptors.
Rose K, Chen N, Andreev A, Chen J, Kefalov VJ, Chen J., | 04/16/2024 |
| Knockout and Replacement Gene Surgery to Treat Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa. | Knockout and Replacement Gene Surgery to Treat Rhodopsin-Mediated Autosomal Dominant Retinitis Pigmentosa.
Sun X, Liang C, Chen Y, Cui T, Han J, Dai M, Zhang Y, Zhou Q, Li W. | 03/20/2024 |
| Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa. | Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa.
Vasudevan S, Senapati S, Pendergast M, Park PS., Free PMC Article | 03/1/2024 |
| Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway. | Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway.
Haggerty KN, Eshelman SC, Sexton LA, Frimpong E, Rogers LM, Agosto MA, Robichaux MA., Free PMC Article | 01/12/2024 |
| Microglia Preserve Visual Function in a Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant. | Microglia Preserve Visual Function in a Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant.
Yu C, Saban DR. | 09/1/2023 |
| Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity. | Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity.
Sun C, Ruzycki PA, Chen S., Free PMC Article | 08/11/2023 |
| Maintenance of optogenetic channel rhodopsin (ChR2) function in aging mice: Implications for pharmacological studies of inhibitory synaptic transmission, quantal content, and calcium homeostasis. | Maintenance of optogenetic channel rhodopsin (ChR2) function in aging mice: Implications for pharmacological studies of inhibitory synaptic transmission, quantal content, and calcium homeostasis.
DuBois DW, Murchison DA, Mahnke AH, Bang E, Winzer-Serhan U, Griffith WH, Souza KA. | 08/7/2023 |
| Structural abnormalities of retinal pigment epithelial cells in a light-inducible, rhodopsin mutant mouse. | Structural abnormalities of retinal pigment epithelial cells in a light-inducible, rhodopsin mutant mouse.
Napoli D, Strettoi E., Free PMC Article | 07/19/2023 |
| Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival. | Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival.
Poria D, Kolesnikov AV, Lee TJ, Salom D, Palczewski K, Kefalov VJ., Free PMC Article | 03/14/2023 |
| Overexpression of Rhodopsin or Its Mutants Leads to Energy Metabolism Dysfunction in 661w Cells. | Overexpression of Rhodopsin or Its Mutants Leads to Energy Metabolism Dysfunction in 661w Cells.
Liu Y, Wang X, Gong R, Xu G, Zhu M., Free PMC Article | 12/17/2022 |
| Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization. | Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization.
Getter T, Kemp A, Vinberg F, Palczewski K., Free PMC Article | 01/29/2022 |
| Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning. | Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.
Rhim I, Coello-Reyes G, Nauhaus I., Free PMC Article | 11/13/2021 |
| Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice. | Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice.
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, Jiang Z, Tian W, Liu W, Zhang S, Yang Y, Jiang L, Zhu X, Zhang L. | 08/14/2021 |
| Retinal degeneration in mice expressing the constitutively active G90D rhodopsin mutant. | Retinal degeneration in mice expressing the constitutively active G90D rhodopsin mutant.
Colozo AT, Vasudevan S, Park PS., Free PMC Article | 07/10/2021 |
| The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice. | The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice.
Lewis TR, Shores CR, Cady MA, Hao Y, Arshavsky VY, Burns ME., Free PMC Article | 01/9/2021 |
| Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis. | Rhodopsin and melanopsin coexist in mammalian sperm cells and activate different signaling pathways for thermotaxis.
Roy D, Levi K, Kiss V, Nevo R, Eisenbach M., Free PMC Article | 11/21/2020 |
| Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation. | Calpain Activation Is the Major Cause of Cell Death in Photoreceptors Expressing a Rhodopsin Misfolding Mutation.
Comitato A, Schiroli D, Montanari M, Marigo V. | 11/21/2020 |
| Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival. | Syntaxin 3 is essential for photoreceptor outer segment protein trafficking and survival.
Kakakhel M, Tebbe L, Makia MS, Conley SM, Sherry DM, Al-Ubaidi MR, Naash MI., Free PMC Article | 10/24/2020 |
| Enigmatic rhodopsin mutation creates an exceptionally strong splice acceptor site. | Enigmatic rhodopsin mutation creates an exceptionally strong splice acceptor site.
Riedmayr LM, Böhm S, Biel M, Becirovic E. | 10/24/2020 |
| These data demonstrated that loss of Tmem30a in mouse cone cells leads to mislocalization of cone opsin, loss of photopic electroretinogram (ERG) responses and loss of cone cells. | Loss of Tmem30a leads to photoreceptor degeneration.
Zhang L, Yang Y, Li S, Zhang S, Zhu X, Tai Z, Yang M, Liu Y, Guo X, Chen B, Jiang Z, Lu F, Zhu X., Free PMC Article | 04/20/2019 |
| Autosomal dominant retinitis pigmentosa rhodopsin mutant Q344X drives specific alterations in chromatin complex gene transcription. | Autosomal dominant retinitis pigmentosa rhodopsin mutant Q344X drives specific alterations in chromatin complex gene transcription.
Bales KL, Ianov L, Kennedy AJ, Sweatt JD, Gross AK., Free PMC Article | 11/17/2018 |
| we show that OPN2 and OPN4 participate in immediate pigment darkening induced by UVA in murine normal and malignant melanocytes through a conserved common pathway | Melanopsin and rhodopsin mediate UVA-induced immediate pigment darkening: Unravelling the photosensitive system of the skin.
de Assis LVM, Moraes MN, Magalhães-Marques KK, Castrucci AML. | 09/1/2018 |
| Photoactivation of rhodopsin increases near-Infrared backscattering from rods and causes lengthening of their rod outer segment. | In vivo optophysiology reveals that G-protein activation triggers osmotic swelling and increased light scattering of rod photoreceptors.
Zhang P, Zawadzki RJ, Goswami M, Nguyen PT, Yarov-Yarovoy V, Burns ME, Pugh EN Jr., Free PMC Article | 05/19/2018 |
| Specific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent beta3-adrenergic signaling. | Specific visible radiation facilitates lipolysis in mature 3T3-L1 adipocytes via rhodopsin-dependent β3-adrenergic signaling.
Park PJ, Cho JY, Cho EG. | 03/17/2018 |