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    Mgl2 macrophage galactose N-acetyl-galactosamine specific lectin 2 [ Mus musculus (house mouse) ]

    Gene ID: 216864, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD301b[+] macrophage: the new booster for activating bone regeneration in periodontitis treatment.

    CD301b(+) macrophage: the new booster for activating bone regeneration in periodontitis treatment.
    Wang C, Zhao Q, Chen C, Li J, Zhang J, Qu S, Tang H, Zeng H, Zhang Y., Free PMC Article

    06/7/2023
    Effective CD4 T cell priming requires repertoire scanning by CD301b(+) migratory cDC2 cells upon lymph node entry.

    Effective CD4 T cell priming requires repertoire scanning by CD301b(+) migratory cDC2 cells upon lymph node entry.
    Tatsumi N, Codrington AL, El-Fenej J, Phondge V, Kumamoto Y., Free PMC Article

    03/12/2022
    The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2).

    The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2).
    da Costa V, van Vliet SJ, Carasi P, Frigerio S, García PA, Croci DO, Festari MF, Costa M, Landeira M, Rodríguez-Zraquia SA, Cagnoni AJ, Cutine AM, Rabinovich GA, Osinaga E, Mariño KV, Freire T.

    01/8/2022
    CD301b/MGL2(+) Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis.

    CD301b/MGL2(+) Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis.
    Meier LA, Auger JL, Engelson BJ, Cowan HM, Breed ER, Gonzalez-Torres MI, Boyer JD, Verma M, Marath A, Binstadt BA., Free PMC Article

    08/10/2019
    Reconstituting RELMalpha in CD301b(+) MNP-depleted animals restored body weight.

    CD301b(+) Mononuclear Phagocytes Maintain Positive Energy Balance through Secretion of Resistin-like Molecule Alpha.
    Kumamoto Y, Camporez JPG, Jurczak MJ, Shanabrough M, Horvath T, Shulman GI, Iwasaki A., Free PMC Article

    09/9/2017
    CD301b dermal dendritic cells drive T helper 2 cell-mediated immunity.

    CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity.
    Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A., Free PMC Article

    12/14/2013
    analysis of macrophage galactose-type C-type lectin 2 (MGL2/CD301b) uptake and presentation of glycosylated antigens by dendritic cells

    Distribution and function of macrophage galactose-type C-type lectin 2 (MGL2/CD301b): efficient uptake and presentation of glycosylated antigens by dendritic cells.
    Denda-Nagai K, Aida S, Saba K, Suzuki K, Moriyama S, Oo-Puthinan S, Tsuiji M, Morikawa A, Kumamoto Y, Sugiura D, Kudo A, Akimoto Y, Kawakami H, Bovin NV, Irimura T., Free PMC Article

    07/26/2010
    The results demonstrated the availability of MGL2 as a novel marker for DDCs and suggested the contribution of MGL2(+) DDCs for initiating CHS.

    MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo.
    Kumamoto Y, Denda-Nagai K, Aida S, Higashi N, Irimura T., Free PMC Article

    01/21/2010
    Mutations of MGL2 CRD at Leu, Arg, Arg, and Tyr at positions 61, 89, 115 and 125 were implicated in the preference for beta-GalNAc.

    The amino acids involved in the distinct carbohydrate specificities between macrophage galactose-type C-type lectins 1 and 2 (CD301a and b) of mice.
    Oo-Puthinan S, Maenuma K, Sakakura M, Denda-Nagai K, Tsuiji M, Shimada I, Nakamura-Tsuruta S, Hirabayashi J, Bovin NV, Irimura T.

    01/21/2010
    The mMGL2 protein is induced in diverse populations of aaMF, including peritoneal macrophages elicited during infection with the protozoan Trypanosoma brucei brucei or the Helminth Taenia crassiceps and alveolar macrophages elicited.

    Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation.
    Raes G, Brys L, Dahal BK, Brandt J, Grooten J, Brombacher F, Vanham G, Noël W, Bogaert P, Boonefaes T, Kindt A, Van den Bergh R, Leenen PJ, De Baetselier P, Ghassabeh GH.

    01/21/2010
    Molecular cloning and expression of mMGL2

    Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1.
    Tsuiji M, Fujimori M, Ohashi Y, Higashi N, Onami TM, Hedrick SM, Irimura T.

    01/21/2010
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