| FANCD2 genome binding is nonrandom and is enriched at large transcriptionally active neural genes prone to copy number variation. | FANCD2 genome binding is nonrandom and is enriched at large transcriptionally active neural genes prone to copy number variation.
Blaize JL, Garzon JLN, Howlett NG., Free PMC Article | 10/18/2024 |
| FANCD2 counteracts O[6]-methylguanine-induced mismatch repair-dependent apoptosis. | FANCD2 counteracts O(6)-methylguanine-induced mismatch repair-dependent apoptosis.
Morita S, Fujikane R, Uechi Y, Matsuura T, Hidaka M. | 10/1/2024 |
| FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions. | FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.
Alcón P, Kaczmarczyk AP, Ray KK, Liolios T, Guilbaud G, Sijacki T, Shen Y, McLaughlin SH, Sale JE, Knipscheer P, Rueda DS, Passmore LA., Free PMC Article | 09/18/2024 |
| Pancancer analysis of the prognostic and immunological role of FANCD2: a potential target for carcinogenesis and survival. | Pancancer analysis of the prognostic and immunological role of FANCD2: a potential target for carcinogenesis and survival.
Zhao Z, Wang R, Wang R, Song J, Ma F, Pan H, Gao C, Wang D, Chen X, Fan X., Free PMC Article | 03/7/2024 |
| FANCD2 deficiency sensitizes SHH medulloblastoma to radiotherapy via ferroptosis. | FANCD2 deficiency sensitizes SHH medulloblastoma to radiotherapy via ferroptosis.
Zhou H, Wang YX, Wu M, Lan X, Xiang D, Cai R, Ma Q, Miao J, Fang X, Wang J, Luo D, He Z, Cui Y, Liang P, Wang Y, Bian XW. | 03/6/2024 |
| Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ. | Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ.
Traband EL, Hammerlund SR, Shameem M, Narayan A, Ramana S, Tella A, Sobeck A, Shima N., Free PMC Article | 02/1/2024 |
| FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination. | FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination.
Leung W, Baxley RM, Traband E, Chang YC, Rogers CB, Wang L, Durrett W, Bromley KS, Fiedorowicz L, Thakar T, Tella A, Sobeck A, Hendrickson EA, Moldovan GL, Shima N, Bielinsky AK., Free PMC Article | 01/5/2024 |
| FANCD2 as a novel prognostic biomarker correlated with immune and drug therapy in Hepatitis B-related hepatocellular carcinoma. | FANCD2 as a novel prognostic biomarker correlated with immune and drug therapy in Hepatitis B-related hepatocellular carcinoma.
Tang X, Luo B, Huang S, Jiang J, Chen Y, Ren W, Shi X, Zhang W, Shi L, Zhong X, Lü M., Free PMC Article | 11/3/2023 |
| FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress. | FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress.
Brunner A, Li Q, Fisicaro S, Kourtesakis A, Viiliäinen J, Johansson HJ, Pandey V, Mayank AK, Lehtiö J, Wohlschlegel JA, Spruck C, Rantala JK, Orre LM, Sangfelt O., Free PMC Article | 10/30/2023 |
| FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability. | FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.
Liu W, Polaczek P, Roubal I, Meng Y, Choe WC, Caron MC, Sedgeman CA, Xi Y, Liu C, Wu Q, Zheng L, Masson JY, Shen B, Campbell JL., Free PMC Article | 09/26/2023 |
| LncRNA SNHG1 upregulates FANCD2 and G6PD to suppress ferroptosis by sponging miR-199a-5p/3p in hepatocellular carcinoma. | LncRNA SNHG1 upregulates FANCD2 and G6PD to suppress ferroptosis by sponging miR-199a-5p/3p in hepatocellular carcinoma.
Zhou L, Zhang Q, Cheng J, Shen X, Li J, Chen M, Zhou C, Zhou J. | 09/20/2023 |
| FANCD2 inhibits ferroptosis by regulating the JAK2/STAT3 pathway in osteosarcoma. | FANCD2 inhibits ferroptosis by regulating the JAK2/STAT3 pathway in osteosarcoma.
Li X, Liu J., Free PMC Article | 02/24/2023 |
| FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells. | FANCD2 promotes mitotic rescue from transcription-mediated replication stress in SETX-deficient cancer cells.
Said M, Barra V, Balzano E, Talhaoui I, Pelliccia F, Giunta S, Naim V., Free PMC Article | 01/28/2023 |
| Optimized structure of monoubiquitinated FANCD2 (human) at Lys 561: a theoretical approach. | Optimized structure of monoubiquitinated FANCD2 (human) at Lys 561: a theoretical approach.
Mondal S, Reddy S, Mukhopadhyay SS. | 01/11/2023 |
| RAD18 opposes transcription-associated genome instability through FANCD2 recruitment. | RAD18 opposes transcription-associated genome instability through FANCD2 recruitment.
Wells JP, Chang EY, Dinatto L, White J, Ryall S, Stirling PC., Free PMC Article | 12/31/2022 |
| FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value. | FANCD2 promotes the malignant behavior of endometrial cancer cells and its prognostic value.
Zheng C, Ren Z, Chen H, Yuan X, Suye S, Yin H, Zhou Z, Fu C. | 12/3/2022 |
| The AICD fragment of APP initiates a FoxO3a mediated response via FANCD2. | The AICD fragment of APP initiates a FoxO3a mediated response via FANCD2.
Greenwood EK, Angelova DM, Büchner HMI, Brown DR. | 09/24/2022 |
| Mechanism, specificity, and function of FANCD2-FANCI ubiquitination and deubiquitination. | Mechanism, specificity, and function of FANCD2-FANCI ubiquitination and deubiquitination.
Lemonidis K, Arkinson C, Rennie ML, Walden H. | 08/27/2022 |
| Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia. | Loss of FANCD2 and related proteins may predict malignant transformation in oral epithelial dysplasia.
Ho MW, Ryan MP, Gupta J, Triantafyllou A, Risk JM, Shaw RJ, Wilson JB. | 03/26/2022 |
| Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination. | Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination.
Ishiai M., Free PMC Article | 02/19/2022 |
| Focal Point of Fanconi Anemia Signaling. | Focal Point of Fanconi Anemia Signaling.
Zhan S, Siu J, Wang Z, Yu H, Bezabeh T, Deng Y, Du W, Fei P., Free PMC Article | 12/25/2021 |
| FANCI functions as a repair/apoptosis switch in response to DNA crosslinks. | FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Shah RB, Kernan JL, van Hoogstraten A, Ando K, Li Y, Belcher AL, Mininger I, Bussenault AM, Raman R, Ramanagoudr-Bhojappa R, Huang TT, D'Andrea AD, Chandrasekharappa SC, Aggarwal AK, Thompson R, Sidi S., Free PMC Article | 11/13/2021 |
| FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability. | FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability.
Fernandes P, Miotto B, Saint-Ruf C, Said M, Barra V, Nähse V, Ravera S, Cappelli E, Naim V., Free PMC Article | 08/14/2021 |
| Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery. | Functional cross talk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery.
Raghunandan M, Yeo JE, Walter R, Saito K, Harvey AJ, Ittershagen S, Lee EA, Yang J, Hoatlin ME, Bielinsky AK, Hendrickson EA, Schärer O, Sobeck A., Free PMC Article | 08/7/2021 |
| Whole exome sequencing identifies a novel FANCD2 gene splice site mutation associated with disease progression in chronic myeloid leukemia: Implication in targeted therapy of advanced phase CML. | Whole exome sequencing identifies a novel FANCD2 gene splice site mutation associated with disease progression in chronic myeloid leukemia: Implication in targeted therapy of advanced phase CML.
Absar M, Mahmood A, Akhtar T, Basit S, Ramzan K, Jameel A, Afzal S, Ullah A, Qureshi K, Alanazi N, Iqbal Z. | 08/7/2021 |