| Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-kappaB Activation through Phosphorylated STAT3-TET3 Signaling. | Transglutaminase 3 Attenuates Skin Inflammation in Psoriasis by Inhibiting NF-κB Activation through Phosphorylated STAT3-TET3 Signaling.
Ling S, Xu B, Luo Y, Fang X, Liu X, Wang A, Zhou Y, Zhang S, Zong W, Li W, Yao X. | 10/29/2022 |
| study concludes that the classic wellhaarig mutations result from defects in Tgm3 | The mouse wellhaarig (we) mutations result from defects in epidermal-type transglutaminase 3 (Tgm3).
Brennan BM, Huynh MT, Rabah MA, Shaw HE, Bisaillon JJ, Radden LA 2nd, Nguyen TV, King TR., Free PMC Article | 09/3/2016 |
| Fluctuations of BMP2 signaling pathway during hair cycles in skin with mutant genes we, wal and Fgf5(go). | Fluctuations of BMP signaling pathway during hair cycles in skin of mice with mutant genes we, wal and Fgf5(go).
Nesterova A, Nizamutdinov I, Golovatenko-Abramov P, Konyukhov B. | 05/31/2016 |
| The mutant gene we is probably responsible for a disrupted induction signal from the dermal papilla towards ectodermal cells of a hair follicle. | [Effects of the mutant gene wellhaarig in chimeric mice].
Martynova MIu, Isaev DA, Koniukhov BV. | 05/31/2016 |
| Interaction of mutant genes Fgf5(go-Y), we, and wal changes the duration of hair growth cycles in mice | [Interaction of mutant genes Fgf5(go-Y), we, and wal changes the duration of hair growth cycles in mice].
Nesterova AP, Nizamutdinov II, Koniukhov BV. | 05/31/2016 |
| The first signs of alopecia in mice of the +/Fgf5(go-Y) we/wewal/wal genotype appear only three days later than in double +/+ we/wewal/wal homozygotes. | [The angora gene weakens the effect of interaction of the mutant genes wellhaarig and waved alopecia in mice].
Koniukhov BV, Nesterova AP, Malinina NA. | 05/31/2016 |
| The clinically uninvolved skin in TGM3 knockout mice showed impaired barrier function and higher susceptibility to FITC sensitization indicating that TGM3 has a significant contribution to the functionally intact cutaneous barrier. | Reduced inflammatory threshold indicates skin barrier defect in transglutaminase 3 knockout mice.
Bognar P, Nemeth I, Mayer B, Haluszka D, Wikonkal N, Ostorhazi E, John S, Paulsson M, Smyth N, Pasztoi M, Buzas EI, Szipocs R, Kolonics A, Temesvari E, Karpati S. | 03/8/2014 |
| Loss of Tgm3 is associated with defective hair development. | Epidermal transglutaminase (TGase 3) is required for proper hair development, but not the formation of the epidermal barrier.
John S, Thiebach L, Frie C, Mokkapati S, Bechtel M, Nischt R, Rosser-Davies S, Paulsson M, Smyth N., Free PMC Article | 08/25/2012 |
| new information on the specific distribution of TGase 3 | Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles.
Yamane A, Fukui M, Sugimura Y, Itoh M, Alea MP, Thomas V, El Alaoui S, Akiyama M, Hitomi K. | 09/27/2010 |
| N-terminus sequence of the proteolyzed fragment was analyzed with specific antibodies. | Immunological detection of proteolytically activated epidermal-type transglutaminase (TGase 3) using cleavage-site-specific antibody.
Hitomi K, Ikeda N, Maki M. | 01/21/2010 |
| detected two splicing variants for TG3, as the transcription of these mRNAs appears to be not regulated during differentiation and in pathologies involving tranglutaminase activity | Identification of transglutaminase 3 splicing isoforms.
Zocchi L, Terrinoni A, Candi E, Ahvazi B, Bagetta G, Corasaniti MT, Lena AM, Melino G. | 01/21/2010 |
| The expression of TGM3 may play a important role in the epidermis differentiation in embryogenesis. | Transglutaminase 3 expression in C57BL/6J mouse embryo epidermis and the correlation with its differentiation.
Zhang J, Zhi HY, Ding F, Luo AP, Liu ZH. | 01/21/2010 |