| GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4. | GABPA inhibits tumorigenesis in clear cell renal cell carcinoma by regulating ferroptosis through ACSL4.
Wu Y, Wu Z, Yao M, Liu L, Song Y, Ma L, Liu C., Free PMC Article | 11/7/2024 |
| ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells. | ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells.
Rupa D, Chuang HW, Hu CE, Su WM, Wu SR, Lee HS, Yuan TC., Free PMC Article | 10/18/2024 |
| ACSL4-Mediated Membrane Phospholipid Remodeling Induces Integrin beta1 Activation to Facilitate Triple-Negative Breast Cancer Metastasis. | ACSL4-Mediated Membrane Phospholipid Remodeling Induces Integrin β1 Activation to Facilitate Triple-Negative Breast Cancer Metastasis.
Qiu Y, Wang X, Sun Y, Jin T, Tang R, Zhou X, Xu M, Gan Y, Wang R, Luo H, Liu M, Tang X., Free PMC Article | 09/3/2024 |
| The m[6]A eraser FTO suppresses ferroptosis via mediating ACSL4 in LPS-induced macrophage inflammation. | The m(6)A eraser FTO suppresses ferroptosis via mediating ACSL4 in LPS-induced macrophage inflammation.
Zhao Y, Ding W, Cai Y, Li Q, Zhang W, Bai Y, Zhang Y, Xu Q, Feng Z. | 08/19/2024 |
| Silencing CK19 regulates ferroptosis by affecting the expression of GPX4 and ACSL4 in oral squamous cell carcinoma in vivo and in vitro. | Silencing CK19 regulates ferroptosis by affecting the expression of GPX4 and ACSL4 in oral squamous cell carcinoma in vivo and in vitro.
Rao Y, Li J, Shi L, Chen X, Hu Y, Mao Y, Zhang X, Liu X., Free PMC Article | 08/6/2024 |
| SIAH2-Mediated Degradation of ACSL4 Inhibits the Anti-Tumor Activity of CD8+ T Cells in Hepatocellular Carcinoma. | SIAH2-Mediated Degradation of ACSL4 Inhibits the Anti-Tumor Activity of CD8+ T Cells in Hepatocellular Carcinoma.
Shu F, Shi Y, Shan X, Zha W, Fan R, Xue W. | 06/14/2024 |
| ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription. | ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription.
Wu D, Zuo Z, Sun X, Li X, Yin F, Yin W. | 06/5/2024 |
| Long-chain acyl-CoA synthetase-4 regulates endometrial decidualization through a fatty acid beta-oxidation pathway rather than lipid droplet accumulation. | Long-chain acyl-CoA synthetase-4 regulates endometrial decidualization through a fatty acid β-oxidation pathway rather than lipid droplet accumulation.
Zhang H, Sun Q, Dong H, Jin Z, Li M, Jin S, Zeng X, Fan J, Kong Y., Free PMC Article | 05/30/2024 |
| METTL3 promotes trophoblast ferroptosis in preeclampsia by stabilizing the ACSL4 m[6]A modification. | METTL3 promotes trophoblast ferroptosis in preeclampsia by stabilizing the ACSL4 m(6)A modification.
Wang Y, Zhang G, Gao Y, Zhang X, Qi H. | 04/11/2024 |
| Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer. | Autocrine phosphatase PDP2 inhibits ferroptosis by dephosphorylating ACSL4 in the Luminal A Breast Cancer.
Zhu JJ, Huang FY, Chen H, Zhang YL, Chen MH, Wu RH, Dai SZ, He GS, Tan GH, Zheng WP., Free PMC Article | 03/14/2024 |
| The ERK-cPLA2-ACSL4 axis mediating M2 macrophages ferroptosis impedes mucosal healing in ulcerative colitis. | The ERK-cPLA2-ACSL4 axis mediating M2 macrophages ferroptosis impedes mucosal healing in ulcerative colitis.
Ye Y, Liu L, Feng Z, Liu Y, Miao J, Wei X, Li H, Yang J, Cao X, Zhao J. | 03/6/2024 |
| Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4-mediated ferroptosis. | Loss of nephric augmenter of liver regeneration facilitates acute kidney injury via ACSL4-mediated ferroptosis.
Huang L, Zhang L, Zhang Z, Tan F, Ma Y, Zeng X, Cao D, Deng L, Liu Q, Sun H, Shen B, Liao X., Free PMC Article | 02/9/2024 |
| Serum ACSL4 levels in patients with ST-segment elevation myocardial infarction (STEMI) and its association with one-year major adverse cardiovascular events (MACE): A prospective cohort study. | Serum ACSL4 levels in patients with ST-segment elevation myocardial infarction (STEMI) and its association with one-year major adverse cardiovascular events (MACE): A prospective cohort study.
Hu Y, Li Q, Wang Y., Free PMC Article | 02/6/2024 |
| RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4. | RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.
Wang C, Chen Z, Yi Y, Ding Y, Xu F, Kang H, Lin K, Shu X, Zhong Z, Zhang Z, Liu J, Xu Z, Liu L, He X, Chang Y, Zhao Q. | 01/31/2024 |
| SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1. | SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J., Free PMC Article | 01/12/2024 |
| miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4. | miRNA-211 maintains metabolic homeostasis in medulloblastoma through its target gene long-chain acyl-CoA synthetase 4.
Yuan M, Mahmud I, Katsushima K, Joshi K, Saulnier O, Pokhrel R, Lee B, Liyanage W, Kunhiraman H, Stapleton S, Gonzalez-Gomez I, Kannan RM, Eisemann T, Kolanthai E, Seal S, Garrett TJ, Abbasi S, Bockley K, Hanes J, Chapagain P, Jallo G, Wechsler-Reya RJ, Taylor MD, Eberhart CG, Ray A, Perera RJ., Free PMC Article | 12/29/2023 |
| Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis. | Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis.
Habaxi K, Wang W, Taximaimaiti M, Wang L. | 12/20/2023 |
| MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis. | MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis.
Phadnis VV, Snider J, Varadharajan V, Ramachandiran I, Deik AA, Lai ZW, Kunchok T, Eaton EN, Sebastiany C, Lyakisheva A, Vaccaro KD, Allen J, Yao Z, Wong V, Geng B, Weiskopf K, Clish CB, Brown JM, Stagljar I, Weinberg RA, Henry WS., Free PMC Article | 10/11/2023 |
| LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity. | LPCAT3 Is Transcriptionally Regulated by YAP/ZEB/EP300 and Collaborates with ACSL4 and YAP to Determine Ferroptosis Sensitivity.
Cui J, Wang Y, Tian X, Miao Y, Ma L, Zhang C, Xu X, Wang J, Fang W, Zhang X. | 09/19/2023 |
| Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer. | Inhibition of CDK1 Overcomes Oxaliplatin Resistance by Regulating ACSL4-mediated Ferroptosis in Colorectal Cancer.
Zeng K, Li W, Wang Y, Zhang Z, Zhang L, Zhang W, Xing Y, Zhou C., Free PMC Article | 09/7/2023 |
| Inhibition of ACSL4 Alleviates Parkinsonism Phenotypes by Reduction of Lipid Reactive Oxygen Species. | Inhibition of ACSL4 Alleviates Parkinsonism Phenotypes by Reduction of Lipid Reactive Oxygen Species.
Tang F, Zhou LY, Li P, Jiao LL, Chen K, Guo YJ, Ding XL, He SY, Dong B, Xu RX, Xiong H, Lei P., Free PMC Article | 08/30/2023 |
| ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma. | ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H. | 08/30/2023 |
| Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis. | Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
Zhang M, Yu Z, Zhao L, Luo H. | 06/7/2023 |
| ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in Hepatocellular Carcinoma. | ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in Hepatocellular Carcinoma.
Yang H, Sun W, Bi T, Sun J, Lu Z, Li J, Wei H. | 06/7/2023 |
| ACSL4: a double-edged sword target in multiple myeloma, promotes cell proliferation and sensitizes cell to ferroptosis. | ACSL4: a double-edged sword target in multiple myeloma, promotes cell proliferation and sensitizes cell to ferroptosis.
Zhang J, Liu Y, Li Q, Zuo L, Zhang B, Zhao F, Fan F, Luo S, Hu Y, Sun C. | 05/31/2023 |