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    Tnf tumor necrosis factor [ Mus musculus (house mouse) ]

    Gene ID: 21926, updated on 9-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Tumor necrosis factor alpha induces NOX2-dependent reactive oxygen species production in hypothalamic paraventricular nucleus neurons following angiotensin II infusion.

    Tumor necrosis factor alpha induces NOX2-dependent reactive oxygen species production in hypothalamic paraventricular nucleus neurons following angiotensin II infusion.
    Woods C, Wang G, Milner TA, Glass MJ.

    11/6/2024
    Tumour necrosis factor alpha regulates the miR-27a-3p-Sfrp1 axis in a mouse model of osteoporosis.

    Tumour necrosis factor α regulates the miR-27a-3p-Sfrp1 axis in a mouse model of osteoporosis.
    Zhang DF, Jin XN, Ma X, Qiu YS, Ma W, Dai X, Zhang Z., Free PMC Article

    07/11/2024
    TNF-alpha/Stearate Induced H3K9/18 Histone Acetylation Amplifies IL-6 Expression in 3T3-L1 Mouse Adipocytes.

    TNF-α/Stearate Induced H3K9/18 Histone Acetylation Amplifies IL-6 Expression in 3T3-L1 Mouse Adipocytes.
    Bahman F, Al-Roub A, Akhter N, Al Madhoun A, Wilson A, Almansour N, Al-Rashed F, Sindhu S, Al-Mulla F, Ahmad R., Free PMC Article

    07/5/2024
    TNF-alpha can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone-invasive pituitary adenoma.

    TNF-α can promote membrane invasion by activating the MAPK/MMP9 signaling pathway through autocrine in bone-invasive pituitary adenoma.
    Wu X, Gong L, Li B, Bai J, Li C, Zhang Y, Zhu H., Free PMC Article

    06/27/2024
    Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia.

    Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia.
    Kruckow KL, Murray E, Shayhidin E, Rosenberg AF, Bowdish DME, Orihuela CJ., Free PMC Article

    06/15/2024
    Microglial TNFalpha controls daily changes in synaptic GABAARs and sleep slow waves.

    Microglial TNFα controls daily changes in synaptic GABAARs and sleep slow waves.
    Pinto MJ, Bizien L, Fabre JMJ, Ðukanović N, Lepetz V, Henderson F, Pujol M, Sala RW, Tarpin T, Popa D, Triller A, Léna C, Fabre V, Bessis A., Free PMC Article

    05/7/2024
    Bub1 suppresses inflammatory arthritis-associated bone loss in mice through inhibition of TNFalpha-mediated osteoclastogenesis.

    Bub1 suppresses inflammatory arthritis-associated bone loss in mice through inhibition of TNFα-mediated osteoclastogenesis.
    Yoshida S, Ikedo A, Yanagihara Y, Sakaue T, Saeki N, Imai Y., Free PMC Article

    04/30/2024
    Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-alpha in rheumatoid arthritis.

    Proinflammatory phenotype of B10 and B10pro cells elicited by TNF-α in rheumatoid arthritis.
    Hu F, Shi L, Liu X, Chen Y, Zhang X, Jia Y, Liu X, Guo J, Zhu H, Liu H, Xu L, Li Y, Wang P, Fang X, Xue J, Xie Y, Wei C, Song J, Zheng X, Liu YY, Li Y, Ren L, Xu D, Lu L, Qiu X, Mu R, He J, Wang M, Zhang X, Liu W, Li Z.

    04/25/2024
    TNFalpha: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease.

    TNFα: TNFR1 signaling inhibits maturation and maintains the pro-inflammatory programming of monocyte-derived macrophages in murine chronic granulomatous disease.
    Gibbings SL, Haist KC, Redente EF, Henson PM, Bratton DL., Free PMC Article

    04/17/2024
    GSK3beta/NF-kappaB -dependent transcriptional regulation of homeostatic hepatocyte Tnf production.

    GSK3β/NF-κB -dependent transcriptional regulation of homeostatic hepatocyte Tnf production.
    Grayck MR, McCarthy WC, Solar M, Golden E, Balasubramaniyan N, Zheng L, Sherlock LG, Wright CJ.,

    03/26/2024
    TNF-alpha protects from exacerbated myocarditis and cardiac death by suppressing expansion of activated heart-reactive CD4+ T cells.

    TNF-α protects from exacerbated myocarditis and cardiac death by suppressing expansion of activated heart-reactive CD4+ T cells.
    Rolski F, Tkacz K, Węglarczyk K, Kwiatkowski G, Pelczar P, Jaźwa-Kusior A, Bar A, Kuster GM, Chłopicki S, Siedlar M, Kania G, Błyszczuk P., Free PMC Article

    03/1/2024
    Knockout of the Tnfa Gene Decreases Influenza Virus-Induced Histological Reactions in Laboratory Mice.

    Knockout of the Tnfa Gene Decreases Influenza Virus-Induced Histological Reactions in Laboratory Mice.
    Savenkova DA, Gudymo AS, Korablev AN, Taranov OS, Bazovkina DV, Danilchenko NV, Perfilyeva ON, Ivleva EK, Moiseeva AA, Bulanovich YA, Roshchina EV, Serova IA, Battulin NR, Kulikova EA, Yudkin DV., Free PMC Article

    02/28/2024
    TET1-mediated epigenetic regulation of tumor necrosis factor-alpha in trigeminal ganglia contributes to chronic temporomandibular joint pain.

    TET1-mediated epigenetic regulation of tumor necrosis factor-α in trigeminal ganglia contributes to chronic temporomandibular joint pain.
    Wang Z, Ma H, Nasir A, Liu S, Li Z, Tao F, Bai Q.

    02/16/2024
    TNF- alpha from the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy.

    TNF- α from the Proximal Nephron Exacerbates Aristolochic Acid Nephropathy.
    Wen Y, Lu X, Privratsky JR, Ren J, Ali S, Yang B, Rudemiller NP, Zhang J, Nedospasov SA, Crowley SD., Free PMC Article

    02/14/2024
    MicroRNA-18a regulates the Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) of osteoblasts induced by tumor necrosis factor-alpha via hypoxia-inducible factor-1alpha.

    MicroRNA-18a regulates the Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) of osteoblasts induced by tumor necrosis factor-α via hypoxia-inducible factor-1α.
    Zhang W, Xia CL, Qu YD, Li JX, Liu JB, Ou SJ, Yang Y, Qi Y, Xu CP.

    02/13/2024
    Mouse Trophoblast Cells Have Attenuated Responses to TNF-alpha and IFN-gamma and Can Avoid Synergic Cytotoxicity of the Two Cytokines.

    Mouse Trophoblast Cells Have Attenuated Responses to TNF-α and IFN-γ and Can Avoid Synergic Cytotoxicity of the Two Cytokines.
    Fendereski M, Ming H, Jiang Z, Guo YL.,

    01/9/2024
    Blood-brain barrier dysfunction mediated by the EZH2-Claudin-5 axis drives stress-induced TNF-alpha infiltration and depression-like behaviors.

    Blood-brain barrier dysfunction mediated by the EZH2-Claudin-5 axis drives stress-induced TNF-α infiltration and depression-like behaviors.
    Sun ZW, Wang X, Zhao Y, Sun ZX, Wu YH, Hu H, Zhang L, Wang SD, Li F, Wei AJ, Feng H, Xie F, Qian LJ.

    12/26/2023
    Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice.

    Cardiomyocyte and endothelial cells play distinct roles in the tumour necrosis factor (TNF)-dependent atrial responses and increased atrial fibrillation vulnerability induced by endurance exercise training in mice.
    Lakin R, Polidovitch N, Yang S, Parikh M, Liu X, Debi R, Gao X, Chen W, Guzman C, Yakobov S, Izaddoustdar F, Wauchop M, Lei Q, Xu W, Nedospasov SA, Christoffels VM, Backx PH., Free PMC Article

    12/23/2023
    Increased contractile activity and dilation of popliteal lymphatic vessels in the TNF-alpha-overexpressing TNF[DeltaARE/+] arthritic mouse.

    Increased contractile activity and dilation of popliteal lymphatic vessels in the TNF-α-overexpressing TNF(ΔARE/+) arthritic mouse.
    de Jesus FN, von der Weid PY.

    12/5/2023
    Disruption of TNF-alpha signaling improves osteoblastic differentiation of adipose-derived mesenchymal stem cells and bone repair.

    Disruption of TNF-α signaling improves osteoblastic differentiation of adipose-derived mesenchymal stem cells and bone repair.
    Bighetti-Trevisan RL, Bueno NP, Souza ATP, Marques MM, Rosa AL, Beloti MM, Ferraz EP.

    11/2/2023
    Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.

    Epithelial TNF controls cell differentiation and CFTR activity to maintain intestinal mucin homeostasis.
    Reyes EA, Castillo-Azofeifa D, Rispal J, Wald T, Zwick RK, Palikuqi B, Mujukian A, Rabizadeh S, Gupta AR, Gardner JM, Boffelli D, Gartner ZJ, Klein OD., Free PMC Article

    11/1/2023
    TNF-alpha-TNFR1 Signaling Mediates Inflammation and Bone Resorption in Apical Periodontitis.

    TNF-α-TNFR1 Signaling Mediates Inflammation and Bone Resorption in Apical Periodontitis.
    Almeida-Junior LA, de Carvalho MS, Almeida LKY, Silva-Sousa AC, Sousa-Neto MD, Silva RAB, Silva LAB, Paula-Silva FWG.

    10/10/2023
    MiR-142-3p is a Critical Modulator of TNF-mediated Neuronal Toxicity in Multiple Sclerosis.

    MiR-142-3p is a Critical Modulator of TNF-mediated Neuronal Toxicity in Multiple Sclerosis.
    De Vito F, Balletta S, Caioli S, Musella A, Guadalupi L, Vanni V, Fresegna D, Bassi MS, Gilio L, Sanna K, Gentile A, Bruno A, Dolcetti E, Buttari F, Pavone L, Furlan R, Finardi A, Perlas E, Hornstein E, Centonze D, Mandolesi G., Free PMC Article

    10/6/2023
    The TNFalpha/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis.

    The TNFα/TNFR2 axis mediates natural killer cell proliferation by promoting aerobic glycolysis.
    Khan AUH, Ali AK, Marr B, Jo D, Ahmadvand S, Fong-McMaster C, Almutairi SM, Wang L, Sad S, Harper ME, Lee SH., Free PMC Article

    10/2/2023
    Dkk-1-TNF-alpha crosstalk regulates MC3T3E1 pre-osteoblast proliferation and differentiation under mechanical stress through the ERK signaling pathway.

    Dkk-1-TNF-α crosstalk regulates MC3T3E1 pre-osteoblast proliferation and differentiation under mechanical stress through the ERK signaling pathway.
    Wu Y, Jing Z, Deng D, Yan J, Liu M, Li L, Zuo Y, Wu W, Hu Q, Xie Y.

    09/27/2023
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