ASB3 expression aggravates inflammatory bowel disease by targeting TRAF6 protein stability and affecting the intestinal microbiota.
Cheng M, Xu B, Sun Y, Wang J, Lu Y, Shi C, Pan T, Zhao W, Li X, Song X, Wang J, Wang N, Yang W, Jiang Y, Huang H, Yang G, Zeng Y, Yang D, Wang C, Cao X., Free PMC Article

14-3-3ζ suppresses RANKL signaling by destabilizing TRAF6.
Ayyasamy R, Fan S, Czernik P, Lecka-Czernik B, Chattopadhyay S, Chakravarti R., Free PMC Article

TRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway.
Zhao Y, Li T, Zhang L, Yang J, Zhao F, Wang Y, Ouyang Y, Liu J., Free PMC Article

Distinct cross talk of IL-17 & TGF-β with the immature CD11c(+) TRAF6((-/-)) -null myeloid dendritic cell-derived osteoclast precursor (mDDOCp) may engage signaling toward an alternative pathway of osteoclastogenesis for arthritic bone loss in vivo.
Liu YCG, Teng AY., Free PMC Article

MiR-31-5p regulates the neuroinflammatory response via TRAF6 in neuropathic pain.
Liu Y, Wang L, Zhou C, Yuan Y, Fang B, Lu K, Xu F, Chen L, Huang L., Free PMC Article

CD4+ T-Cell Legumain Deficiency Attenuates Hypertensive Damage via Preservation of TRAF6.
He Y, Zou P, Lu J, Lu Y, Yuan S, Zheng X, Liu J, Zeng C, Liu L, Tang L, Fang Z, Hu X, Liu Q, Zhou S.

Axonal injury mediated by neuronal p75NTR/TRAF6/JNK pathway contributes to cognitive impairment after repetitive mTBI.
Liu G, He M, Wu C, Lv P, Sun H, Wang H, Xin X, Liao H.

TLR9 regulates the autophagy-lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6-cGAS-STING pathway.
Liu Y, Wei FZ, Zhan YW, Wang R, Mo BY, Lin SD.

The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8(+) T-cell immunity.
Yu J, Cui J, Zhang X, Xu H, Chen Z, Li Y, Niu Y, Wang S, Ran S, Zou Y, Ye W, Zhang D, Zhou C, Xia J, Wu J.,

MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
An Q, Xia J, Pu F, Shi S., Free PMC Article

Rnd3 suppresses endothelial cell pyroptosis in atherosclerosis through regulation of ubiquitination of TRAF6.
Zhang Y, Zhu Z, Cao Y, Xiong Z, Duan Y, Lin J, Zhang X, Jiang M, Liu Y, Man W, Jia T, Feng J, Chen Y, Li C, Guo B, Sun D., Free PMC Article

Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.
Sun J, Xu G.

IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death.
Lee CS, Hwang G, Nam YW, Hwang CH, Song J., Free PMC Article

Annexin A3 accelerates osteoclast differentiation by promoting the level of RANK and TRAF6.
Lin S, Li M, Zhou Y, Chen L, Wang Y, Zhuang Z, Zhao H, Yang R.

TRAF6 controls T cell homeostasis by maintaining the equilibrium of MALT1 scaffolding and protease functions.
O'Neill TJ, Gewies A, Seeholzer T, Krappmann D., Free PMC Article

LncRNA AK089514/miR-125b-5p/TRAF6 axis mediates macrophage polarization in allergic asthma.
Zhu X, He L, Li X, Pei W, Yang H, Zhong M, Zhang M, Lv K, Zhang Y., Free PMC Article

Inhibition of CD40-TRAF6-dependent inflammatory activity halts the onset of diabetic retinopathy in streptozotocin-diabetic mice.
Howell SJ, Lee CA, Zapadka TE, Lindstrom SI, Taylor BE, Taylor ZRR, Barber KG, Taylor PR., Free PMC Article

Regulation of T-independent B-cell responses by microRNA-146a.
King JK, Tran TM, Paing MH, Yin Y, Jaiswal AK, Tso CH, Roy K, Casero D, Rao DS., Free PMC Article

Viperin impairs the innate immune response through the IRAK1-TRAF6-TAK1 axis to promote Mtb infection.
Zhou X, Zhang Z, Xu H, Zhu B, Zhang L, Lie L, Huang Y, Du X, Liu H, Li Y, Huang Y, Hu S, Zhou C, Wen Q, Pepplenbosch MP, Ma L.

The oncogene ABL1 regulates the inflammatory response of innate immunity via mediating TRAF6 ubiquitination.
Xu F, Yao W, Xue Y, Sun Q, Cao C.

Ubiquitin-specific protease 47 regulates intestinal inflammation through deubiquitination of TRAF6 in epithelial cells.
Lei H, Yang L, Xu H, Wang Z, Li X, Liu M, Wu Y.

Gonadal hormone trigger the dynamic microglial alterations through Traf6/TAK1 axis that correlate with depressive behaviors.
Peng R, Dai W, Li D, Li Y.

IFT80 negatively regulates osteoclast differentiation via association with Cbl-b to disrupt TRAF6 stabilization and activation.
Deepak V, Yang ST, Li Z, Li X, Ng A, Xu D, Li YP, Oursler MJ, Yang S., Free PMC Article

Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Liu J, Li S, Fei X, Nan X, Shen Y, Xiu H, Cormier SA, Lu C, Guo C, Wang S, Cai Z, Wang P., Free PMC Article

TRAF6 signaling pathway in T cells regulates anti-tumor immunity through the activation of tumor specific Th9 cells and CTLs.
Dewayani A, Kamiyama N, Sachi N, Ozaka S, Saechue B, Ariki S, Goto M, Chalalai T, Soga Y, Fukuda C, Kagoshima Y, Maekawa Y, Kobayashi T.