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    FCGR1A Fc gamma receptor Ia [ Homo sapiens (human) ]

    Gene ID: 2209, updated on 10-Dec-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis.

    Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis.
    Huang X, Wu L, Ouyang Q, Huang Y, Hong L, Liu S, Yang K, Ning D, Tan CC., Free PMC Article

    03/5/2024
    A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso.

    A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso.
    Cretin J, Adjemout M, Dieppois C, Gallardo F, Torres M, Merard Z, Sawadogo SA, Picard C, Rihet P, Paul P., Free PMC Article

    11/16/2023
    Prognostic performance of neutrophil CD64 expression in patients with complicated intra-abdominal infections - a prospective study.

    Prognostic performance of neutrophil CD64 expression in patients with complicated intra-abdominal infections - a prospective study.
    Dimitrov E, Halacheva K, Minkov G, Enchev E, Yovtchev Y.

    09/6/2023
    CD64 expression on neutrophils as a potential biomarker for bacterial infection in ascitic fluid of cirrhotic patients.

    CD64 expression on neutrophils as a potential biomarker for bacterial infection in ascitic fluid of cirrhotic patients.
    González-López E, Odriozola Herrán A, Renuncio García M, Roa-Bautista A, Antón Rodríguez Á, Comins-Boo A, Irure Ventura J, Puente Á, López-Hoyos M, Fortea JI, San Segundo D.

    07/12/2023
    Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study.

    Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study.
    Huang N, Chen J, Wei Y, Liu Y, Yuan K, Chen J, He M, Liu N., Free PMC Article

    08/13/2022
    Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis.

    Novel Human FCGR1A Variants Affect CD64 Functions and Are Risk Factors for Sarcoidosis.
    Wu J, Li Y, Rendahl A, Bhargava M., Free PMC Article

    04/16/2022
    Soluble FcgammaRIA expressed on monocytes (sCD64): A new serum biomarker of acute kidney injury in patients with suspected infection at emergency department admission.

    Soluble FcγRIA expressed on monocytes (sCD64): A new serum biomarker of acute kidney injury in patients with suspected infection at emergency department admission.
    Mearelli F, Barbati G, Moras C, Ronco C, Biolo G, on the behalf of the Need Speed Group.

    02/19/2022
    Fcgamma receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.

    Fcγ receptor activation mediates vascular inflammation and abdominal aortic aneurysm development.
    Lopez-Sanz L, Bernal S, Jimenez-Castilla L, Prieto I, La Manna S, Gomez-Lopez S, Blanco-Colio LM, Egido J, Martin-Ventura JL, Gomez-Guerrero C., Free PMC Article

    02/5/2022
    Utility of neutrophil CD64 in distinguishing bacterial infection from inflammation in severe alcoholic hepatitis fulfilling SIRS criteria.

    Utility of neutrophil CD64 in distinguishing bacterial infection from inflammation in severe alcoholic hepatitis fulfilling SIRS criteria.
    Pandey G, Singh H, Chaturvedi S, Hatti M, Kumar A, Mishra R, Mishra P, Krishna VP, Bhadauria A, Mohindra S, Misra DP, Saraswat VA, Agarwal V., Free PMC Article

    01/1/2022
    CD169 and CD64 could help differentiate bacterial from CoVID-19 or other viral infections in the Emergency Department.

    CD169 and CD64 could help differentiate bacterial from CoVID-19 or other viral infections in the Emergency Department.
    Bourgoin P, Soliveres T, Barbaresi A, Loundou A, Belkacem IA, Arnoux I, Bernot D, Loosveld M, Morange PE, Michelet P, Malergue F, Markarian T., Free PMC Article

    05/22/2021
    Differential expression of CD64 in patients with Mycobacterium tuberculosis infection: A potential biomarker for clinical diagnosis and prognosis.

    Differential expression of CD64 in patients with Mycobacterium tuberculosis infection: A potential biomarker for clinical diagnosis and prognosis.
    Liu Q, Gao Y, Ou Q, Xu Y, Zhou Z, Li T, Lu Y, Sun F, Zhou X, Li Y, Shao L, Zhang W., Free PMC Article

    05/15/2021
    CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same.

    CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same.
    García-Salido A, Cuenca-Carcelén S, Castillo-Robleda A., Free PMC Article

    02/6/2021
    Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors.

    Ozone-derived oxysterols impair lung macrophage phagocytosis via adduction of some phagocytosis receptors.
    Duffney PF, Kim HH, Porter NA, Jaspers I., Free PMC Article

    02/2/2021
    Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors.

    Design and characterization of novel dual Fc antibody with enhanced avidity for Fc receptors.
    Goulet DR, Zwolak A, Williams JA, Chiu ML, Atkins WM., Free PMC Article

    01/9/2021
    Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages.

    Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages.
    Orsó E, Robenek H, Boettcher A, Wolf Z, Liebisch G, Kramer W, Schmitz G.

    08/22/2020
    binding by sTLT1 initiates inflammatory signals in macrophages

    Elevated level of circulatory sTLT1 induces inflammation through SYK/MEK/ERK signalling in coronary artery disease.
    Das AA, Chakravarty D, Bhunia D, Ghosh S, Mandal PC, Siddiqui KN, Bandyopadhyay A.

    05/30/2020
    Cd64 is up-regulated in neutrophils, but HLA-DR antigens are down-regulated in monocytes in septic shock patients.

    A novel one-step extracellular staining for flow cytometry: Proof-of-concept on sepsis-related biomarkers.
    Bourgoin P, Hayman J, Rimmelé T, Venet F, Malergue F, Monneret G.

    05/9/2020
    Hepatitis E virus ORF3 could significantly impair the phagocytosis of macrophage by downregulating expression of CD14 and CD64, which may function by inhibiting the activation of the JAK1/STAT1 signaling pathway.

    HEV ORF3 downregulatesCD14 and CD64 to impair macrophages phagocytosis through inhibiting JAK/STAT pathway.
    Lei Q, Li L, Huang W, Qin B, Zhang S.

    03/28/2020
    IGF1R prognosticates prolonged survival in HGSOC patients, possibly due to its positive correlation with hCtr1

    IGF1R predicts better survival in high-grade serous epithelial ovarian cancer patients and correlates with hCtr1 levels.
    Deo A, Chaudhury S, Kannan S, Rekhi B, Maheshwari A, Gupta S, Ray P.

    03/21/2020
    The neutrophil CD64 index is a valuable biomarker for diagnosing sepsis in patients in the intensive care unit.

    Diagnostic performance of neutrophil CD64 index in patients with sepsis in the intensive care unit.
    Ye Z, Zou H, Liu S, Mei C, Chang X, Hu Z, Yang H, Wu Y., Free PMC Article

    03/21/2020
    Data suggest that polymorphonuclear cells (PMNs) CD64 index is sensitive and specific for neonatal pneumonia (NP) diagnosis.

    CD64 Expression on Polymorph Nuclear Cells as a Sensitive and Specific Diagnostic Biomarker for Neonate Pneumonia.
    Xu J, Ban Y, Wan Z, Mai Q, Ou J, Feng G, Yang G, Pan H, Zhang F.

    12/21/2019
    FcGR1A gene expression is associated with tuberculosis in the HIV infected patients.

    "Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets".
    Verma S, Du P, Nakanjako D, Hermans S, Briggs J, Nakiyingi L, Ellner JJ, Manabe YC, Salgame P., Free PMC Article

    06/15/2019
    The logistic regression model emphasized the performance of FcgammaRI, FcgammaRII and IL-10 as robust predictive biomarkers for post-therapeutic cicatrization during cutaneous leishmaniasis.

    Fcγ-RI, Fcγ-RII and IL-10 as predictive biomarkers for post-therapeutic cicatrization time in monocytes from cutaneous leishmaniasis patients.
    Rodrigues-Alves ML, Melo-Júnior OAO, Coelho-Dos-Reis JG, Pascoal-Xavier MA, Alves-Costa H, Reis CA, Dutra WO, Silva RE, Senna MCR, Faria AC, Medeiros NI, Gomes JAS, Silveira-Lemos D, Martins-Filho OA, Teixeira-Carvalho A, Costa-Silva MF, Giunchetti RC, Peruhype-Magalhães V.

    05/18/2019
    surface expression of CD64 on circulating monocytes reflects systemic inflammation, renal injury and could be used as a rapid approach and good biomarker for disease activity and lupus nephritis in systemic lupus erythematosus patients

    Expression of CD64 on Surface of Circulating Monocytes in Systemic Lupus Erythematosus Patients: Relation to Disease Activity and Lupus Nephritis.
    Abd-Elhamid YA, Eltanawy RM, Fawzy RM, Fouad NA, Atlm AM.

    04/27/2019
    neutrophil CD64, CD11b and Lipocalin-2 are early, specific and sensitive diagnostic markers of neonatal sepsis

    Neutrophil CD11b, CD64 and Lipocalin-2: Early Diagnostic Markers of Neonatal Sepsis.
    Sheneef A, Mohamed T, Boraey NF, Mohammed MA.

    04/27/2019
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