| Knockdown of ARL5B Induces Mitochondrial-mediated Apoptosis and Inhibits Glycolysis in Breast Cancer Cells by Activating MDA5 Signaling. | Knockdown of ARL5B Induces Mitochondrial-mediated Apoptosis and Inhibits Glycolysis in Breast Cancer Cells by Activating MDA5 Signaling.
Zhang L, Hu X, Wu H, Tian H, Zeng J, Song D, Yang K, Chen J, Xu J, Dong F. | 10/8/2022 |
| Interacting partners of Golgi-localized small G protein Arl5b identified by a combination of in vivo proximity labelling and GFP-Trap pull down. | Interacting partners of Golgi-localized small G protein Arl5b identified by a combination of in vivo proximity labelling and GFP-Trap pull down.
Houghton FJ, Makhoul C, Cho EH, Williamson NA, Gleeson PA. | 10/8/2022 |
| Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B. | Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B.
Jaimon E, Tripathi A, Khurana A, Ghosh D, Sugatha J, Datta S., Free PMC Article | 01/29/2022 |
| miR-145 inhibits mitochondrial function of ovarian cancer by targeting ARL5B. | miR-145 inhibits mitochondrial function of ovarian cancer by targeting ARL5B.
Zhao S, Zhang Y, Pei M, Wu L, Li J., Free PMC Article | 09/4/2021 |
| Advanced glycation end products reduce macrophage-mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation. | Advanced glycation end products reduce macrophage-mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation.
Xie X, Yang C, Duan C, Chen H, Zeng T, Huang S, Li H, Ren M, Lin WJ, Yan L. | 12/19/2020 |
| Depletion of either Arl5b or AP4 results in the accumulation of APP. | Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway.
Toh WH, Tan JZ, Zulkefli KL, Houghton FJ, Gleeson PA. | 09/16/2017 |
| Arl5b is a trans-golgi-network-localised small G protein that plays a key role in regulating transport along the endosome-trans-golgi network pathway | Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.
Houghton FJ, Bellingham SA, Hill AF, Bourges D, Ang DK, Gemetzis T, Gasnereau I, Gleeson PA. | 04/7/2012 |
| Arl8 and SKIP are required for lysosomes to distribute away from the microtubule-organizing center. We identify two kinesin light chain binding motifs in SKIP that are required for lysosomes to accumulate kinesin-1 and redistribute to the cell periphery. | Arl8 and SKIP act together to link lysosomes to kinesin-1.
Rosa-Ferreira C, Munro S., Free PMC Article | 02/18/2012 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Genome-wide association reveals genetic effects on human Aβ42 and τ protein levels in cerebrospinal fluids: a case control study.
Han MR, Schellenberg GD, Wang LS, Alzheimer's Disease Neuroimaging Initiative., Free PMC Article | 12/5/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article | 12/2/2009 |
| ARL8 contains six exons and five introns, and encodes a 179 amino acid protein that shares homology to the other ARL proteins. | Isolation of a new member of the ADP-ribosylation like factor gene family, ARL8, from a cartilage cDNA library.
Sebald E, Krueger R, King LM, Cohn DH, Krakow D. | 01/21/2010 |