| JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy. | JAZF1: A Metabolic Regulator of Sensitivity to a Polyamine-Targeted Therapy.
Rosario SR, Jacobi JJ, Long MD, Affronti HC, Rowsam AM, Smiraglia DJ., Free PMC Article | 01/11/2023 |
| Rs864745 in JAZF1, an Islet Function Associated Variant, Correlates With Plasma Lipid Levels in Both Type 1 and Type 2 Diabetes Status, but Not Healthy Subjects. | Rs864745 in JAZF1, an Islet Function Associated Variant, Correlates With Plasma Lipid Levels in Both Type 1 and Type 2 Diabetes Status, but Not Healthy Subjects.
Dai H, Qian Y, Lv H, Jiang L, Jiang H, Shen M, Chen H, Chen Y, Zheng S, Fu Q, Yang T, Xu K., Free PMC Article | 07/23/2022 |
| JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation. | JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation.
Tavares M, Khandelwal G, Muter J, Viiri K, Beltran M, Brosens JJ, Jenner RG., Free PMC Article | 06/11/2022 |
| Down-regulation of the transcriptional repressor ZNF802 (JAZF1) reactivates fetal hemoglobin in beta(0)-thalassemia/HbE. | Down-regulation of the transcriptional repressor ZNF802 (JAZF1) reactivates fetal hemoglobin in β(0)-thalassemia/HbE.
Wongborisuth C, Chumchuen S, Sripichai O, Anurathaphan U, Sathirapongsasuti N, Songdej D, Tangprasittipap A, Hongeng S., Free PMC Article | 04/23/2022 |
| RNA-driven JAZF1-SUZ12 gene fusion in human endometrial stromal cells. | RNA-driven JAZF1-SUZ12 gene fusion in human endometrial stromal cells.
Gupta SK, Jea JD, Yen L., Free PMC Article | 02/19/2022 |
| Correlation analysis of epicardial adipose tissue thickness, C-reactive protein, interleukin-6, visfatin, juxtaposed with another zinc finger protein 1, and type 2 diabetic macroangiopathy. | Correlation analysis of epicardial adipose tissue thickness, C-reactive protein, interleukin-6, visfatin, juxtaposed with another zinc finger protein 1, and type 2 diabetic macroangiopathy.
Gong YY, Peng HY., Free PMC Article | 09/11/2021 |
| The relationship between chimeric RNAs and gene fusions: Potential implications of reciprocity in cancer. | The relationship between chimeric RNAs and gene fusions: Potential implications of reciprocity in cancer.
Elfman J, Pham LP, Li H., Free PMC Article | 07/10/2021 |
| TFAP2B, AP-1 and JAZF1 Expression in Tissues of Papillary Thyroid Carcinoma Patients; Clinical, Pathological and Prognostic Values. | TFAP2B, AP-1 and JAZF1 Expression in Tissues of Papillary Thyroid Carcinoma Patients; Clinical, Pathological and Prognostic Values.
A Abuderman A, A Harb O, M Gertallah L, Makki Almansour N., Free PMC Article | 06/5/2021 |
| The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress. | The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress.
Kobiita A, Godbersen S, Araldi E, Ghoshdastider U, Schmid MW, Spinas G, Moch H, Stoffel M. | 05/1/2021 |
| This review provides an update of the latest research advances on JAZF1 and its regulatory network in T2 diabetes mellitus (T2DM). The association between JAZF1 polymorphisms and T2DM is discussed as well. The information provided is of importance for guiding future studies as well as for the design of JAZF1-based T2DM therapy. [review] | JAZF1, a relevant metabolic regulator in type 2 diabetes.
Liao ZZ, Wang YD, Qi XY, Xiao XH. | 02/8/2020 |
| JAZF1 was identified as a direct miR-1275 target. miR-1275 supresses migration and invasion of gastric cancer cells in vitro and in vivo, which was restored by JAZF1 overexpression. Moreover, JAZF1 was recognized as a direct regulator of Vimentin. | MicroRNA-1275 inhibits cell migration and invasion in gastric cancer by regulating vimentin and E-cadherin via JAZF1.
Mei JW, Yang ZY, Xiang HG, Bao R, Ye YY, Ren T, Wang XF, Shu YJ., Free PMC Article | 01/4/2020 |
| The roles of JAZF1 were partially attenuated by Compound C. | JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism.
Wei Q, Zhou B, Yang G, Hu W, Zhang L, Liu R, Li M, Wang K, Gu HF, Guan Y, Zhu Z, Zheng H, Peng J, Li L., Free PMC Article | 11/16/2019 |
| Case Report: JAZF1/SUZ12 translocation in a low-grade endometrioid stromal sarcoma originating in the paratestis. | Low-grade Endometrioid Stromal Sarcoma of the Paratestis: A Novel Report With Molecular Confirmation of JAZF1/SUZ12 Translocation.
Agaimy A, Moskalev EA, Weisser W, Bach T, Haller F, Hartmann A. | 03/23/2019 |
| We discovered three significant associations at rs6679677 on 1p13.2 (P=6.15x10-5, OR=5.07), rs16861329 on 3q27.3 (P=2.02x10-4, OR=0.87) and rs849135 on 7p15.1 (P=6.59x10-9, OR=1.78), which suggested PTPN22, ST6GAL1 and JAZF1 as novel susceptibility genes for psoriasis in Chinese population. | Identification of PTPN22, ST6GAL1 and JAZF1 as psoriasis risk genes demonstrates shared pathogenesis between psoriasis and diabetes.
Wang H, Wang Z, Rani PL, Fu X, Yu W, Bao F, Yu G, Li J, Li L, Sun L, Yue Z, Zhao Q, Pan Q, Cao J, Wang C, Chi X, Wang Y, Yang Q, Mi Z, Liu H, Zhang F. | 07/21/2018 |
| PNPLA3 and JAZF1 were associated with non-hepatitis B virus and non-hepatitis C virus-related hepatocellular carcinoma development among Japanese patients with type 2 diabetes mellitus | The impact of PNPLA3 and JAZF1 on hepatocellular carcinoma in non-viral hepatitis patients with type 2 diabetes mellitus.
Ueyama M, Nishida N, Korenaga M, Korenaga K, Kumagai E, Yanai H, Adachi H, Katsuyama H, Moriyama S, Hamasaki H, Sako A, Sugiyama M, Aoki Y, Imamura M, Murata K, Masaki N, Kawaguchi T, Torimura T, Hyogo H, Aikata H, Ito K, Sumida Y, Kanazawa A, Watada H, Okamoto K, Honda K, Kon K, Kanto T, Mizokami M, Watanabe S. | 01/14/2017 |
| study found SNP rs7754840 in CDKAL1, rs864745 in JAZF1, and rs35767 in IGF1 might serve as potential susceptibility loci for type 2 diabetes in the Uyghur population | The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CDKAL1, JAZF1, and IGF1 genes.
Song M, Zhao F, Ran L, Dolikun M, Wu L, Ge S, Dong H, Gao Q, Zhai Y, Zhang L, Yan Y, Liu F, Yang X, Guo X, Wang Y, Wang W., Free PMC Article | 03/26/2016 |
| genetic association study in Han population in China: Data suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is associated with recurrent pregnancy loss; SNPs in KIAA0319L [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated. | Association between KIAA0319L, PXK and JAZF1 gene polymorphisms and unexplained recurrent pregnancy loss in Chinese Han couples.
Song G, Yan J, Li G, Chen ZJ. | 12/5/2015 |
| In African American men, the association between JAZF1 rs10486567 and prostate cancer may be modified by exposure to heavy metals such as Pb. | Gene-environment interactions between JAZF1 and occupational and household lead exposure in prostate cancer among African American men.
Neslund-Dudas C, Levin AM, Beebe-Dimmer JL, Bock CH, Nock NL, Rundle A, Jankowski M, Krajenta R, Dou QP, Mitra B, Tang D, Rebbeck TR, Rybicki BA., Free PMC Article | 01/24/2015 |
| study determined that the previously described systemic lupus erythematosus susceptibility loci PXK (P = 3.27 x 10(-11), OR = 1.20) and JAZF1 (P = 1.11 x 10(-8), OR = 1.13) are shared with systemic sclerosis | A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
Martin JE, Assassi S, Diaz-Gallo LM, Broen JC, Simeon CP, Castellvi I, Vicente-Rabaneda E, Fonollosa V, Ortego-Centeno N, González-Gay MA, Espinosa G, Carreira P, Spanish Scleroderma Group, SLEGEN consortium, U.S. Scleroderma GWAS group, BIOLUPUS, Camps M, Sabio JM, D'alfonso S, Vonk MC, Voskuyl AE, Schuerwegh AJ, Kreuter A, Witte T, Riemekasten G, Hunzelmann N, Airo P, Beretta L, Scorza R, Lunardi C, Van Laar J, Chee MM, Worthington J, Herrick A, Denton C, Fonseca C, Tan FK, Arnett F, Zhou X, Reveille JD, Gorlova O, Koeleman BP, Radstake TR, Vyse T, Mayes MD, Alarcón-Riquelme ME, Martin J., Free PMC Article | 03/22/2014 |
| Morphological features, immunoprofile and fluorescence in situ hybridization rearrangements of JAZF1 and PHF1 genes were correlated with tumor category and outcome in endometrial sarcomas | Endometrial sarcomas: an immunohistochemical and JAZF1 re-arrangement study in low-grade and undifferentiated tumors.
Jakate K, Azimi F, Ali RH, Lee CH, Clarke BA, Rasty G, Shaw PA, Melnyk N, Huntsman DG, Laframboise S, Rouzbahman M. | 07/27/2013 |
| genetic association studies in a population in Utah: Data suggest that an SNP in JAZF1 (rs1635852) is associated with type 2 diabetes; this SNP in JAZF1 intron 1 is part of a cis-regulatory complex. | Allele-specific transcriptional activity at type 2 diabetes-associated single nucleotide polymorphisms in regions of pancreatic islet open chromatin at the JAZF1 locus.
Fogarty MP, Panhuis TM, Vadlamudi S, Buchkovich ML, Mohlke KL., Free PMC Article | 06/29/2013 |
| This study indicates a nominal role for JAZF1 and BCL11A variants in type 2 diabetes susceptibility in African-Americans. | Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study.
Langberg KA, Ma L, Sharma NK, Hanis CL, Elbein SC, Hasstedt SJ, Das SK, American Diabetes Association GENNID Study Group., Free PMC Article | 05/19/2012 |
| Observational study of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Impact of single nucleotide polymorphisms and of clinical risk factors on new‐onset diabetes mellitus in HIV‐infected individuals.
Rotger M, Gsponer T, Martinez R, Taffé P, Elzi L, Vernazza P, Cavassini M, Bernasconi E, Hirschel B, Furrer H, Weber R, Ledergerber B, Egger M, Telenti A, Tarr PE, Swiss HIV Cohort Study. | 12/5/2010 |
| Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesMeta-analysis of genome-wide and replication association studies on prostate cancer.
Liu H, Wang B, Han C. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.
Zeggini E, Scott LJ, Saxena R, Voight BF, Marchini JL, Hu T, de Bakker PI, Abecasis GR, Almgren P, Andersen G, Ardlie K, Boström KB, Bergman RN, Bonnycastle LL, Borch-Johnsen K, Burtt NP, Chen H, Chines PS, Daly MJ, Deodhar P, Ding CJ, Doney AS, Duren WL, Elliott KS, Erdos MR, Frayling TM, Freathy RM, Gianniny L, Grallert H, Grarup N, Groves CJ, Guiducci C, Hansen T, Herder C, Hitman GA, Hughes TE, Isomaa B, Jackson AU, Jørgensen T, Kong A, Kubalanza K, Kuruvilla FG, Kuusisto J, Langenberg C, Lango H, Lauritzen T, Li Y, Lindgren CM, Lyssenko V, Marvelle AF, Meisinger C, Midthjell K, Mohlke KL, Morken MA, Morris AD, Narisu N, Nilsson P, Owen KR, Palmer CN, Payne F, Perry JR, Pettersen E, Platou C, Prokopenko I, Qi L, Qin L, Rayner NW, Rees M, Roix JJ, Sandbaek A, Shields B, Sjögren M, Steinthorsdottir V, Stringham HM, Swift AJ, Thorleifsson G, Thorsteinsdottir U, Timpson NJ, Tuomi T, Tuomilehto J, Walker M, Watanabe RM, Weedon MN, Willer CJ, Wellcome Trust Case Control Consortium, Illig T, Hveem K, Hu FB, Laakso M, Stefansson K, Pedersen O, Wareham NJ, Barroso I, Hattersley AT, Collins FS, Groop L, McCarthy MI, Boehnke M, Altshuler D. | 09/15/2010 |
| Single-nucleotide polymorphism of rs10486567 in JAZF1 is associated with prostate cancer. | Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.
Prokunina-Olsson L, Fu YP, Tang W, Jacobs KB, Hayes RB, Kraft P, Berndt SI, Wacholder S, Yu K, Hutchinson A, Spencer Feigelson H, Thun MJ, Diver WR, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Cancel-Tassin G, Cussenot O, Valeri A, Andriole GL, Crawford ED, Haiman CA, Henderson BE, Kolonel L, Le Marchand L, Siddiq A, Riboli E, Travis R, Kaaks R, Isaacs WB, Isaacs SD, Grönberg H, Wiklund F, Xu J, Vatten LJ, Hveem K, Kumle M, Tucker M, Hoover RN, Fraumeni JF Jr, Hunter DJ, Thomas G, Chatterjee N, Chanock SJ, Yeager M., Free PMC Article | 08/23/2010 |