| Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling. | Increased Expression of the Neuropeptides PACAP/VIP in the Brain of Mice with CNS Targeted Production of IL-6 Is Mediated in Part by Trans-Signalling.
Castorina A, Scheller J, Keay KA, Marzagalli R, Rose-John S, Campbell IL., Free PMC Article | 11/7/2024 |
| VIP interneuron impairment promotes in vivo circuit dysfunction and autism-related behaviors in Dravet syndrome. | VIP interneuron impairment promotes in vivo circuit dysfunction and autism-related behaviors in Dravet syndrome.
Goff KM, Liebergall SR, Jiang E, Somarowthu A, Goldberg EM., Free PMC Article | 10/13/2023 |
| VIP interneurons in sensory cortex encode sensory and action signals but not direct reward signals. | VIP interneurons in sensory cortex encode sensory and action signals but not direct reward signals.
Ramamurthy DL, Chen A, Zhou J, Park C, Huang PC, Bharghavan P, Krishna G, Liu J, Casale K, Feldman DE., Free PMC Article | 08/30/2023 |
| Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression. | Donor plasmacytoid dendritic cells limit graft-versus-host disease through vasoactive intestinal polypeptide expression.
Zhu J, Wang Y, Li J, Das PK, Zhang H, Passang T, Li JM, Nagy T, Gandhi K, Ravindranathan S, Giver CR, Hassan M, Li Y, Antonova AU, Wang S, Roback JD, Waller EK., Free PMC Article | 10/1/2022 |
| microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction. | microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction.
Qiu F, Mao X, Liu P, Wu J, Zhang Y, Sun D, Zhu Y, Gong L, Shao M, Fan K, Chen J, Lu J, Jiang Y, Zhang Y, Curia G, Li A, He M. | 11/22/2021 |
| Different Roles for VIP Neurons in the Neonatal and Adult Suprachiasmatic Nucleus. | Different Roles for VIP Neurons in the Neonatal and Adult Suprachiasmatic Nucleus.
Mazuski C, Chen SP, Herzog ED., Free PMC Article | 09/11/2021 |
| The regulatory role of vasoactive intestinal peptide in lacrimal gland ductal fluid secretion: A new piece of the puzzle in tear production. | The regulatory role of vasoactive intestinal peptide in lacrimal gland ductal fluid secretion: A new piece of the puzzle in tear production.
Berczeli O, Szarka D, Elekes G, Vizvári E, Szalay L, Almássy J, Tálosi L, Ding C, Tóth-Molnár E., Free PMC Article | 08/28/2021 |
| Reduced VIP Expression Affects Circadian Clock Function in VIP-IRES-CRE Mice (JAX 010908). | Reduced VIP Expression Affects Circadian Clock Function in VIP-IRES-CRE Mice (JAX 010908).
Joye DAM, Rohr KE, Keller D, Inda T, Telega A, Pancholi H, Carmona-Alcocer V, Evans JA., Free PMC Article | 06/12/2021 |
| Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas. | Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas.
Zhang Y, Gao N, Wu L, Lee PSY, Me R, Dai C, Xie L, Yu FX., Free PMC Article | 01/2/2021 |
| The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit. | The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit.
Patton AP, Edwards MD, Smyllie NJ, Hamnett R, Chesham JE, Brancaccio M, Maywood ES, Hastings MH., Free PMC Article | 09/12/2020 |
| In the brain, VIP plays an important role in CNS development. Its effects are excitatory, inhibitory, biphasic or none, depending on the particular neuron. VIP enhances inhibition imposed on GABAergic interneurons by utilizing pre and postsynaptic receptors. Review. | Updating the picture of layer 2/3 VIP-expressing interneuron function in the mouse cerebral cortex.
Posłuszny A. | 06/20/2020 |
| feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier | Feeding-dependent VIP neuron-ILC3 circuit regulates the intestinal barrier.
Talbot J, Hahn P, Kroehling L, Nguyen H, Li D, Littman DR., Free PMC Article | 06/6/2020 |
| Vasoactive intestinal peptide activation in auditory cortex recovered movement-induced reduction in spike rates, but not information transfer. | Movement and VIP Interneuron Activation Differentially Modulate Encoding in Mouse Auditory Cortex.
Bigelow J, Morrill RJ, Dekloe J, Hasenstaub AR., Free PMC Article | 04/4/2020 |
| Results show that vasoactive intestinal peptide-expressing interneurons (VIP-INs) express the voltage gated sodium (+)) channel subunit Nav1.1.(Nav1.1) and are dysfunctional in Dravet Syndrome (DS), which may contribute to DS pathogenesis. | Vasoactive intestinal peptide-expressing interneurons are impaired in a mouse model of Dravet syndrome.
Goff KM, Goldberg EM., Free PMC Article | 03/7/2020 |
| findings indicate that VIP interneurons are a central component of a dynamic circuit motif that mediates adaptive disinhibitory gating to specifically learn about unexpected, salient events, thereby ensuring appropriate behavioral adaptations. | Adaptive disinhibitory gating by VIP interneurons permits associative learning.
Krabbe S, Paradiso E, d'Aquin S, Bitterman Y, Courtin J, Xu C, Yonehara K, Markovic M, Müller C, Eichlisberger T, Gründemann J, Ferraguti F, Lüthi A. | 02/1/2020 |
| sex- and sub region-dependent modulation of arcuate kisspeptin neurones by vasopressin and vasoactive intestinal peptide | Sex- and sub region-dependent modulation of arcuate kisspeptin neurones by vasopressin and vasoactive intestinal peptide.
Schafer D, Kane G, Colledge WH, Piet R, Herbison AE. | 10/5/2019 |
| In vivo administration of lentivirus expressing VIP exerts a potent therapeutic effect on LPS-induced Acute Lung Injury in mice via inhibiting inflammation. | Vasoactive intestinal peptide overexpression mediated by lentivirus attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation.
Sun GY, Yang HH, Guan XX, Zhong WJ, Liu YP, Du MY, Luo XQ, Zhou Y, Guan CX. | 01/12/2019 |
| A significant myenteric neuronal cell loss and upregulation of VIP expression were found after focal, but not global, cerebral ischaemia. | Focal, but not global, cerebral ischaemia causes loss of myenteric neurons and upregulation of vasoactive intestinal peptide in mouse ileum.
Cheng X, Svensson M, Yang Y, Deierborg T, Ekblad E, Voss U., Free PMC Article | 12/1/2018 |
| Martinotti cells in layers II/III of the mouse primary somatosensory cortex are inhibited by both parvalbumin (PV)- and vasoactive intestinal polypeptide (VIP)-expressing cells. | Parvalbumin- and vasoactive intestinal polypeptide-expressing neocortical interneurons impose differential inhibition on Martinotti cells.
Walker F, Möck M, Feyerabend M, Guy J, Wagener RJ, Schubert D, Staiger JF, Witte M., Free PMC Article | 09/1/2018 |
| BAD phosphorylation is essential in the cytoprotective effect of vasoactive intestinal peptide on cancer stem cells. | Cytoprotective effect of neuropeptides on cancer stem cells: vasoactive intestinal peptide-induced antiapoptotic signaling.
Sastry KS, Chouchane AI, Wang E, Kulik G, Marincola FM, Chouchane L., Free PMC Article | 03/10/2018 |
| The suprachiasmatic nucleus (SCN)network consists of multiple clusters of cellular circadian rhythms that are differentially integrated by AVP and VIP signaling, depending on the postnatal period | Differential roles of AVP and VIP signaling in the postnatal changes of neural networks for coherent circadian rhythms in the SCN.
Ono D, Honma S, Honma K., Free PMC Article | 01/27/2018 |
| PACAP/PAC1 signaling is important for light regulated behavior, VIP/VPAC2 signaling for stable clock function and both signaling pathways may play a role in shaping diurnality versus nocturnality. | PAC1- and VPAC2 receptors in light regulated behavior and physiology: Studies in single and double mutant mice.
Hannibal J, Georg B, Fahrenkrug J., Free PMC Article | 12/23/2017 |
| The data of this study support a key role for VIP interneurons in cortical circuit development and suggest a possible contribution to pathophysiology in neurodevelopmental disorders | Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits.
Batista-Brito R, Vinck M, Ferguson KA, Chang JT, Laubender D, Lur G, Mossner JM, Hernandez VG, Ramakrishnan C, Deisseroth K, Higley MJ, Cardin JA., Free PMC Article | 09/2/2017 |
| During arousal, VIP cells rapidly and directly inhibit pyramidal neurons; VIP cells also indirectly excite these pyramidal neurons via parallel disinhibition. | An inhibitory pull-push circuit in frontal cortex.
Garcia-Junco-Clemente P, Ikrar T, Tring E, Xu X, Ringach DL, Trachtenberg JT., Free PMC Article | 08/26/2017 |
| This study found that VIP-/- mice show a bilateral tactile hypersensitivity after spared nerve injury and a bilateral increase in neuronal activation upon innocuous tactile paw stimulation. | Bilateral tactile hypersensitivity and neuroimmune responses after spared nerve injury in mice lacking vasoactive intestinal peptide.
Gallo A, Leerink M, Michot B, Ahmed E, Forget P, Mouraux A, Hermans E, Deumens R. | 08/19/2017 |