| Regnase-1 D141N mutation induces CD4+ T cell-mediated lung granuloma formation via upregulation of Pim2. | Regnase-1 D141N mutation induces CD4+ T cell-mediated lung granuloma formation via upregulation of Pim2.
Htun TS, Tanaka H, Singh SK, Diez D, Akira S. | 10/31/2024 |
| MCPIP1 modulates the miRNA-mRNA landscape in keratinocyte carcinomas. | MCPIP1 modulates the miRNA‒mRNA landscape in keratinocyte carcinomas.
Lichawska-Cieslar A, Szukala W, Ylla G, Machaj G, Ploskonka F, Chlebicka I, Szepietowski JC, Jura J., Free PMC Article | 10/21/2024 |
| Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression. | Crosstalk between Regnase-1 and -3 shapes mast cell survival and cytokine expression.
Bataclan M, Leoni C, Moro SG, Pecoraro M, Wong EH, Heissmeyer V, Monticelli S., Free PMC Article | 06/12/2024 |
| MCPIP1 Inhibits Hepatic Stellate Cell Activation in Autocrine and Paracrine Manners, Preventing Liver Fibrosis. | MCPIP1 Inhibits Hepatic Stellate Cell Activation in Autocrine and Paracrine Manners, Preventing Liver Fibrosis.
Pydyn N, Ferenc A, Trzos K, Pospiech E, Wilamowski M, Mucha O, Major P, Kadluczka J, Rodrigues PM, Banales JM, Herranz JM, Avila MA, Hutsch T, Malczak P, Radkowiak D, Budzynski A, Jura J, Kotlinowski J., Free PMC Article | 05/28/2024 |
| MCPIP-1-Mediated Immunosuppression of Neutrophils Exacerbates Acute Bacterial Peritonitis and Liver Injury. | MCPIP-1-Mediated Immunosuppression of Neutrophils Exacerbates Acute Bacterial Peritonitis and Liver Injury.
Lin J, Lu Z, Li G, Zhang C, Lu H, Gao S, Zhu R, Huang H, Aden K, Wang J, Cong Y, Wu H, Liu Z., Free PMC Article | 04/10/2024 |
| Lung Epithelial Regnase-1 Dampens Local Immune Response but Does Not Worsen Susceptibility to Klebsiella pneumoniae. | Lung Epithelial Regnase-1 Dampens Local Immune Response but Does Not Worsen Susceptibility to Klebsiella pneumoniae.
Lin B, Fan L, Jackson S, Matunis AR, Lou D, Chen K, Trevejo-Nuñez G., Free PMC Article | 02/6/2024 |
| Hepatic Mcpip1 regulates adaptation to food restriction in mice. | Hepatic Mcpip1 regulates adaptation to food restriction in mice.
Mucha O, Skupien-Rabian B, Slota A, Trzos K, Pydyn N, Podlewski B, Jura J, Kotlinowski J. | 12/27/2023 |
| MCPIP1 alleviates depressive-like behaviors in mice by inhibiting the TLR4/TRAF6/NF-kappaB pathway to suppress neuroinflammation. | MCPIP1 alleviates depressive‑like behaviors in mice by inhibiting the TLR4/TRAF6/NF‑κB pathway to suppress neuroinflammation.
An Q, Xia J, Pu F, Shi S., Free PMC Article | 11/30/2023 |
| MCPIP-1 knockdown enhances endothelial colony-forming cell angiogenesis via the TFRC/AKT/mTOR signaling pathway in the ischemic penumbra of MCAO mice. | MCPIP-1 knockdown enhances endothelial colony-forming cell angiogenesis via the TFRC/AKT/mTOR signaling pathway in the ischemic penumbra of MCAO mice.
Zou X, Xie Y, Zhang Z, Feng Z, Han J, Ouyang Q, Hua S, Huang S, Li C, Liu Z, Cai Y, Zou Y, Tang Y, Chen H, Jiang X. | 11/6/2023 |
| Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation. | Depletion of Mcpip1 in murine myeloid cells results in intestinal dysbiosis followed by allergic inflammation.
Szukala W, Pilarczyk-Zurek M, Folkert J, Kotlinowski J, Koziel J, Jura J. | 08/9/2023 |
| Regnase-1 plays an essential role in maintaining skin immune homeostasis via regulation of chemokine expression. | Regnase-1 plays an essential role in maintaining skin immune homeostasis via regulation of chemokine expression.
Yang G, Lee HE, Trzeciak M, Pawelczyk T, Takeuchi O, Kang HC, Cho YY, Lee HS, Lee JY. | 05/12/2023 |
| Breaking self-regulation of Regnase-1 promotes its own protein expression. | Breaking self-regulation of Regnase-1 promotes its own protein expression.
Piboonprai K, Millius A, Shimoda M, Tanaka H, Akira S, Maeda K. | 05/8/2023 |
| MCPIP1 restrains mucosal inflammation by orchestrating the intestinal monocyte to macrophage maturation via an ATF3-AP1S2 axis. | MCPIP1 restrains mucosal inflammation by orchestrating the intestinal monocyte to macrophage maturation via an ATF3-AP1S2 axis.
Lu H, Zhang C, Wu W, Chen H, Lin R, Sun R, Gao X, Li G, He Q, Gao H, Wu X, Lin J, Zhu R, Niu J, Kolattukudy PE, Liu Z. | 04/6/2023 |
| Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response. | Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response.
Trevejo-Nuñez G, Lin B, Fan L, Aggor FEY, Biswas PS, Chen K, Gaffen SL., Free PMC Article | 03/2/2023 |
| MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis. | MCPIP1 alleviates inflammatory response through inducing autophagy in Aspergillus fumigatus keratitis.
Han F, Shen L, Ma H, Wang L, Guo H, Wu X. | 12/10/2022 |
| MCPIP1 alleviated alcohol-induced immune dysfunction via the MAPK/ERK signaling pathway. | MCPIP1 alleviated alcohol-induced immune dysfunction via the MAPK/ERK signaling pathway.
Shen Y, Zhang K, Wang R, Sun S, Yang Y, Yao Y, Liu H, Ren Z. | 10/29/2022 |
| MCP-Induced Protein 1 Participates in Macrophage-Dependent Endotoxin Tolerance. | MCP-Induced Protein 1 Participates in Macrophage-Dependent Endotoxin Tolerance.
Wadowska M, Dobosz E, Golda A, Bryzek D, Lech M, Fu M, Koziel J. | 10/8/2022 |
| Macrophage-Specific MCPIP1/Regnase-1 Attenuates Kidney Ischemia-Reperfusion Injury by Shaping the Local Inflammatory Response and Tissue Regeneration. | Macrophage-Specific MCPIP1/Regnase-1 Attenuates Kidney Ischemia-Reperfusion Injury by Shaping the Local Inflammatory Response and Tissue Regeneration.
Ribeiro A, Dobosz E, Krill M, Köhler P, Wadowska M, Steiger S, Schmaderer C, Koziel J, Lech M., Free PMC Article | 04/16/2022 |
| Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation. | Murine myeloid cell MCPIP1 suppresses autoimmunity by regulating B-cell expansion and differentiation.
Dobosz E, Lorenz G, Ribeiro A, Würf V, Wadowska M, Kotlinowski J, Schmaderer C, Potempa J, Fu M, Koziel J, Lech M., Free PMC Article | 02/5/2022 |
| Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses. | Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
Behrens G, Edelmann SL, Raj T, Kronbeck N, Monecke T, Davydova E, Wong EH, Kifinger L, Giesert F, Kirmaier ME, Hohn C, de Jonge LS, Pisfil MG, Fu M, Theurich S, Feske S, Kawakami N, Wurst W, Niessing D, Heissmeyer V., Free PMC Article | 01/1/2022 |
| Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts. | Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts.
Pydyn N, Żurawek D, Kozieł J, Kus E, Wojnar-Lason K, Jasztal A, Fu M, Jura J, Kotlinowski J., Free PMC Article | 12/4/2021 |
| IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay. | IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay.
Akaki K, Ogata K, Yamauchi Y, Iwai N, Tse KM, Hia F, Mochizuki A, Ishihama Y, Mino T, Takeuchi O., Free PMC Article | 11/27/2021 |
| Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts. | Subversion of Lipopolysaccharide Signaling in Gingival Keratinocytes via MCPIP-1 Degradation as a Novel Pathogenic Strategy of Inflammophilic Pathobionts.
Gasiorek A, Dobosz E, Potempa B, Ciaston I, Wilamowski M, Oruba Z, Lamont RJ, Jura J, Potempa J, Koziel J., Free PMC Article | 11/13/2021 |
| Regnase-1 is essential for B cell homeostasis to prevent immunopathology. | Regnase-1 is essential for B cell homeostasis to prevent immunopathology.
Bhat N, Virgen-Slane R, Ramezani-Rad P, Leung CR, Chen C, Balsells D, Shukla A, Kao E, Apgar JR, Fu M, Ware CF, Rickert RC., Free PMC Article | 10/9/2021 |
| Deletion of Mcpip1 in Mcpip1(fl/fl)Alb(Cre) mice recapitulates the phenotype of human primary biliary cholangitis. | Deletion of Mcpip1 in Mcpip1(fl/fl)Alb(Cre) mice recapitulates the phenotype of human primary biliary cholangitis.
Kotlinowski J, Hutsch T, Czyzynska-Cichon I, Wadowska M, Pydyn N, Jasztal A, Kij A, Dobosz E, Lech M, Miekus K, Pośpiech E, Fu M, Jura J, Koziel J, Chlopicki S., Free PMC Article | 09/11/2021 |