| Prognostic and Predictive Utility of GPD1L in Human Hepatocellular Carcinoma. | Prognostic and Predictive Utility of GPD1L in Human Hepatocellular Carcinoma.
Leung PKH, Das B, Cheng X, Tarazi M., Free PMC Article | 09/14/2023 |
| GPD1L inhibits renal cell carcinoma progression by regulating PINK1/Parkin-mediated mitophagy. | GPD1L inhibits renal cell carcinoma progression by regulating PINK1/Parkin-mediated mitophagy.
Liu T, Zhu H, Ge M, Pan Z, Zeng Y, Leng Y, Yang K, Cheng F., Free PMC Article | 08/16/2023 |
| Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation. | Atrial myocyte-derived exosomal microRNA contributes to atrial fibrosis in atrial fibrillation.
Hao H, Yan S, Zhao X, Han X, Fang N, Zhang Y, Dai C, Li W, Yu H, Gao Y, Wang D, Gao Q, Duan Y, Yuan Y, Li Y., Free PMC Article | 09/24/2022 |
| GPD1L is negatively associated with HIF1alpha expression and predicts lymph node metastasis in oral and HPV- Oropharyngeal cancer. | GPD1L is negatively associated with HIF1α expression and predicts lymph node metastasis in oral and HPV- Oropharyngeal cancer.
Liu H, Wang S, Cheng A, Han Z, Feng Z, Guo C. | 10/9/2021 |
| A novel mutation in GPD1L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents. | A novel mutation in GPD1‑L associated with early repolarization syndrome via modulation of cardiomyocyte fast sodium currents.
Fan J, Ji CC, Cheng YJ, Yao H, Chen XM, Zheng ZH, Wu SH. | 12/5/2020 |
| Findings indicate that downregulation of NEAT1 aggravated progression of OA via modulating the miR-181a/GPD1L axis, providing a novel insight into the mechanism of OA pathogenesis. | Long Noncoding RNA Nuclear Enriched Abundant Transcript 1 (NEAT1) Regulates Proliferation, Apoptosis, and Inflammation of Chondrocytes via the miR-181a/Glycerol-3-Phosphate Dehydrogenase 1-Like (GPD1L) Axis.
Wang Z, Hao J, Chen D., Free PMC Article | 04/18/2020 |
| This study not only further supported the important role of GPD1L in Cardiac conduction disease, but also expanded the spectrum of GPD1L mutations | Whole-exome sequencing identifies a novel mutation of GPD1L (R189X) associated with familial conduction disease and sudden death.
Huang H, Chen YQ, Fan LL, Guo S, Li JJ, Jin JY, Xiang R., Free PMC Article | 05/4/2019 |
| The elevated levels of both serum Shh and IL-6 were mainly observed in BC patients who had a significantly higher risk of early recurrence and bone metastasis, and associated with a worse survival for patients with progressive metastatic BC. | A Systems Genetics Approach Identified GPD1L and its Molecular Mechanism for Obesity in Human Adipose Tissue.
He H, Sun D, Zeng Y, Wang R, Zhu W, Cao S, Bray GA, Chen W, Shen H, Sacks FM, Qi L, Deng HW., Free PMC Article | 12/22/2018 |
| Then bioinformatic analysis identified potential target sites of the miR-181a located in the 3' untranslated region of GPD1L. Increased GPD1L and decreased miRNA-181a were observed in tissues from osteoarthritis patients. Our results demonstrated that miR-181a may play an important role in the pathogenesis of Osteoarthritis through targeting GPD1L and regulating chondrocyte apoptosis. | miR-181a Modulates Chondrocyte Apoptosis by Targeting Glycerol-3-Phosphate Dehydrogenase 1-Like Protein (GPD1L) in Osteoarthritis.
Zhai X, Meng R, Li H, Li J, Jing L, Qin L, Gao Y., Free PMC Article | 05/27/2017 |
| In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes. | The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.
Winkel BG, Yuan L, Olesen MS, Sadjadieh G, Wang Y, Risgaard B, Jabbari R, Haunsø S, Holst AG, Hollegaard MV, Tfelt-Hansen J, Jespersen T. | 03/12/2016 |
| The results of real-time PCR showed that, compared with the paired normal tissues, mRNA levels of GPD1L were decreased significantly in head and neck squamous cell carcinoma. | The prognostic value of glycerol-3-phosphate dehydrogenase 1-like expression in head and neck squamous cell carcinoma.
Feng Z, Li JN, Wang L, Pu YF, Wang Y, Guo CB. | 09/27/2014 |
| Common variations in or near CASQ2, GPD1L, and NOS1AP are associated with increased risk of sudden cardiac death in patients with coronary artery disease | Common variants in CASQ2, GPD1L, and NOS1AP are significantly associated with risk of sudden death in patients with coronary artery disease.
Westaway SK, Reinier K, Huertas-Vazquez A, Evanado A, Teodorescu C, Navarro J, Sinner MF, Gunson K, Jui J, Spooner P, Kaab S, Chugh SS., Free PMC Article | 02/18/2012 |
| hypoxia-induced miR-210 represses GPD1L, contributing to suppression of prolyl hydroxylases activity, and increases of HIF-1alpha protein levels. | A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1alpha stability through miR-210 suppression of glycerol-3-phosphate dehydrogenase 1-like.
Kelly TJ, Souza AL, Clish CB, Puigserver P., Free PMC Article | 08/27/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Mutations of GPD1-L may downregulate Na(v)1.5 by altering the oxidized to reduced NAD(H) balance. | Cardiac Na+ current regulation by pyridine nucleotides.
Liu M, Sanyal S, Gao G, Gurung IS, Zhu X, Gaconnet G, Kerchner LJ, Shang LL, Huang CL, Grace A, London B, Dudley SC Jr., Free PMC Article | 01/21/2010 |
| GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A. | GPD1L links redox state to cardiac excitability by PKC-dependent phosphorylation of the sodium channel SCN5A.
Valdivia CR, Ueda K, Ackerman MJ, Makielski JC., Free PMC Article | 01/21/2010 |
| No non-synonymous mutations were found, indicating that GPD1L does not appear to be a major cause of Brugada syndrome in a Japanese population. | Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome.
Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M, Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Mutation analysis of the glycerol-3 phosphate dehydrogenase-1 like (GPD1L) gene in Japanese patients with Brugada syndrome.
Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M, Makiyama T, Akao M, Haruna Y, Tsuji K, Doi T, Ohno S, Nishio Y, Kita T, Horie M. | 09/10/2008 |
| A GPD1-L mutation decreases SCN5A surface membrane expression, reduces inward Na+ current, and causes Brugada syndrome | Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias.
London B, Michalec M, Mehdi H, Zhu X, Kerchner L, Sanyal S, Viswanathan PC, Pfahnl AE, Shang LL, Madhusudanan M, Baty CJ, Lagana S, Aleong R, Gutmann R, Ackerman MJ, McNamara DM, Weiss R, Dudley SC Jr., Free PMC Article | 01/21/2010 |
| mutations in GPD1-L as a pathogenic cause for a small subset of sudden infant death syndrome via a secondary loss-of-function mechanism | Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome.
Van Norstrand DW, Valdivia CR, Tester DJ, Ueda K, London B, Makielski JC, Ackerman MJ., Free PMC Article | 01/21/2010 |