| Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/alpha-tubulin acetylation. | Autophagic degradation of KAT2A/GCN5 promotes directional migration of vascular smooth muscle cells by reducing TUBA/α-tubulin acetylation.
Ouyang C, Mu J, Lu Q, Li J, Zhu H, Wang Q, Zou MH, Xie Z., Free PMC Article | 10/2/2021 |
| DNMBP loss-of-function variants cause infantile-onset cataracts in humans. | Bi-allelic Loss-of-Function Variants in DNMBP Cause Infantile Cataracts.
Ansar M, Chung HL, Taylor RL, Nazir A, Imtiaz S, Sarwar MT, Manousopoulou A, Makrythanasis P, Saeed S, Falconnet E, Guipponi M, Pournaras CJ, Ansari MA, Ranza E, Santoni FA, Ahmed J, Shah I, Gul K, Black GC, Bellen HJ, Antonarakis SE., Free PMC Article | 05/18/2019 |
| The rs3740058 in DNMBP was significantly differently in genotype between Alaheimer diease and control in APOE epsilon4epsilon4 subgroup, but showed no effect on Alzheimer disease risk, either did rs11190305 polymorphisms in DNMBP. | Genetic association of CUGBP2 and DNMBP with Alzheimer' s disease in the Chinese Han population.
Yang P, Xu M, Liu Z, Tao Q, Lu S, Li H, Guo Q, Sun Y, Wu Z. | 12/19/2015 |
| Cdc42 and its specific guanine nucleotide-exchange factor (GEF), Tuba, localize to linear invadosomes, and both are required for linear invadosome formation | Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.
Juin A, Di Martino J, Leitinger B, Henriet E, Gary AS, Paysan L, Bomo J, Baffet G, Gauthier-Rouvière C, Rosenbaum J, Moreau V, Saltel F., Free PMC Article | 03/21/2015 |
| Polyproline region of N-WASP is required for the localization of Tuba at the pre-apical patch. | Tuba and N-WASP function cooperatively to position the central lumen during epithelial cyst morphogenesis.
Kovacs EM, Verma S, Thomas SG, Yap AS., Free PMC Article | 12/24/2011 |
| findings underscore a role for DNMBP in the genetic risk for late-onset Alzheimer's disease in the Belgian population | DNMBP is genetically associated with Alzheimer dementia in the Belgian population.
Bettens K, Brouwers N, Engelborghs S, De Pooter T, De Deyn PP, Sleegers K, Van Broeckhoven C, Bettens K, Brouwers N, Engelborghs S, De Pooter T, De Deyn PP, Sleegers K, Van Broeckhoven C. | 01/21/2010 |
| Although DNMBP is an excellent candidate gene because of its role in the APP recycling pathways and being located within a chromosome 10 linkage region, we are unable to confirm that DNMBP is associated with LOAD | Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J, Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. | 01/21/2010 |
| We observed no association of statistical significance in either the total sample or the APOE*4 non-carriers for any of the SNPs of Dynamin Binding Protein. | No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease.
Minster RL, DeKosky ST, Kamboh MI, Minster RL, DeKosky ST, Kamboh MI., Free PMC Articles: PMC2553275, PMC2553275 | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesAssociation analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J, Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. No association of dynamin binding protein (DNMBP) gene SNPs and Alzheimer's disease.
Minster RL, DeKosky ST, Kamboh MI, Minster RL, DeKosky ST, Kamboh MI. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A. | 03/13/2008 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | See all PubMed (2) articlesDNMBP is genetically associated with Alzheimer dementia in the Belgian population.
Bettens K, Brouwers N, Engelborghs S, De Pooter T, De Deyn PP, Sleegers K, Van Broeckhoven C, Bettens K, Brouwers N, Engelborghs S, De Pooter T, De Deyn PP, Sleegers K, Van Broeckhoven C. Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease.
Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Japanese Genetic Study Consortium for Alzeheimer's Disease, Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Japanese Genetic Study Consortium for Alzeheimer's Disease. | 03/13/2008 |
| Results confirmed DNMBP may be one of the susceptibility genes for Alzheimer's disease. | Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease.
Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Japanese Genetic Study Consortium for Alzeheimer's Disease, Kuwano R, Miyashita A, Arai H, Asada T, Imagawa M, Shoji M, Higuchi S, Urakami K, Kakita A, Takahashi H, Tsukie T, Toyabe S, Akazawa K, Kanazawa I, Ihara Y, Japanese Genetic Study Consortium for Alzeheimer's Disease. | 01/21/2010 |
| functions to bring together dynamin with actin regulatory proteins | Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.
Salazar MA, Kwiatkowski AV, Pellegrini L, Cestra G, Butler MH, Rossman KL, Serna DM, Sondek J, Gertler FB, De Camilli P. | 01/21/2010 |
| Tuba controls the shaping of cell junctions through the local activation of Cdc42 and its effectors. | Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells.
Otani T, Ichii T, Aono S, Takeichi M., Free PMC Article | 01/21/2010 |