| Polymorphisms in the choline transporter SLC44A1 are associated with reduced cognitive performance in normotypic but not prenatal alcohol-exposed children. | Polymorphisms in the choline transporter SLC44A1 are associated with reduced cognitive performance in normotypic but not prenatal alcohol-exposed children.
Smith SM, Weathers TD, Virdee MS, Schwantes-An TH, Voruganti VS, Mattson SN, Coles CD, Kable JA, Sowell E, Wozniak JR, Wetherill L, Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD) Consortium., Free PMC Article | 01/11/2024 |
| Functional Expression of Choline Transporters in Human Neural Stem Cells and Its Link to Cell Proliferation, Cell Viability, and Neurite Outgrowth. | Functional Expression of Choline Transporters in Human Neural Stem Cells and Its Link to Cell Proliferation, Cell Viability, and Neurite Outgrowth.
Fujita Y, Nagakura T, Uchino H, Inazu M, Yamanaka T., Free PMC Article | 08/28/2021 |
| Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters. | Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters.
Taylor A, Grapentine S, Ichhpuniani J, Bakovic M., Free PMC Article | 08/21/2021 |
| Protein kinase C promotes choline transporterlike protein 1 function via improved cell surface expression in immortalized human hepatic cells. | Protein kinase C promotes choline transporter‑like protein 1 function via improved cell surface expression in immortalized human hepatic cells.
Ishikawa T, Suwanai H, Shikuma J, Suzuki R, Yamanaka T, Odawara M, Inazu M., Free PMC Article | 10/10/2020 |
| Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. | Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration.
Fagerberg CR, Taylor A, Distelmaier F, Schrøder HD, Kibæk M, Wieczorek D, Tarnopolsky M, Brady L, Larsen MJ, Jamra RA, Seibt A, Hejbøl EK, Gade E, Markovic L, Klee D, Nagy P, Rouse N, Agarwal P, Dolinsky VW, Bakovic M. | 08/22/2020 |
| SLC44A1 acts as a choline transporter both in the plasma membrane and in the mitochondria. Novel aspects of choline transport regulation in the muscle, nervous system, and cancer are reviewed. Review. | Choline transport for phospholipid synthesis: An emerging role of choline transporter-like protein 1.
Hedtke V, Bakovic M., Free PMC Article | 06/20/2020 |
| Study of genome-wide epigenetic changes in bronchial epithelial cells of asthmatic patients, following cells treatment with vitamin D3 and Poly (I:C)(a viral analogue) allows the identification of biologically plausible candidate genes for viral infections and asthma, such as DUSP10 and SLC44A1. | Epigenome-wide effects of vitamin D on asthma bronchial epithelial cells.
Boutaoui N, Puranik S, Zhang R, Wang T, Hui DH, Brehm J, Forno E, Chen W, Celedón JC., Free PMC Article | 05/30/2020 |
| SLC44A1 and KLF13 may be involved in tumorigenesis and the metastasis of colon cancer by miRNA regulation | Integrated analysis of gene expression signatures associated with colon cancer from three datasets.
Gao P, He M, Zhang C, Geng C. | 04/14/2018 |
| The differential expression pattern of CTL1 and CTL2 suggests that CTL1 is the key transporter involved in choline transport from maternal circulation and both transporters are likely involved in stromal and endothelial cell choline transport. | Characterization of choline transporters in the human placenta over gestation.
Baumgartner HK, Trinder KM, Galimanis CE, Post A, Phang T, Ross RG, Winn VD., Free PMC Article | 10/8/2016 |
| This study showed that SLC44A1-PRKCA fusion seems to be a specific characteristic of Papillary glioneuronal tumors with a high diagnostic value. | Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion.
Pages M, Lacroix L, Tauziede-Espariat A, Castel D, Daudigeos-Dubus E, Ridola V, Gilles S, Fina F, Andreiuolo F, Polivka M, Lechapt-Zalcman E, Puget S, Boddaert N, Liu XQ, Bridge JA, Grill J, Chretien F, Varlet P., Free PMC Article | 05/28/2016 |
| Reduced CTL1 expression is associated with postural orthostatic tachycardia syndrome. | Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts.
Schenkel LC, Singh RK, Michel V, Zeisel SH, da Costa KA, Johnson AR, Mudd HS, Bakovic M., Free PMC Article | 08/1/2015 |
| NCI-H69 cells express the choline transporter CTL1 which uses a directed H(+) gradient as a driving force, and its transport functions in co-operation with NHE1. | Functional expression of choline transporter-like protein 1 (CTL1) in small cell lung carcinoma cells: a target molecule for lung cancer therapy.
Inazu M, Yamada T, Kubota N, Yamanaka T. | 04/19/2014 |
| REVIEW highlights discovery and characterization of SLC44A1, describes its expression patterns and subcellular localization and summarizes evidence for the role of this choline transporter in the central nervous system. | The ubiquitous choline transporter SLC44A1.
Michel V, Bakovic M. | 06/15/2013 |
| CTL1 is expressed in both SH-SY5Y and LA-N-2 cells and is responsible for choline uptake that relies on a directed hydrogen ion gradient as a driving force. | Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis.
Yamada T, Inazu M, Tajima H, Matsumiya T. | 12/31/2011 |
| In conclusion, choline transport in A549 cells is increased by treatment with DEX, and the increase is mediated by induction of functional choline transporters CTL1 and CTL2. | Involvement of choline transporter-like proteins, CTL1 and CTL2, in glucocorticoid-induced acceleration of phosphatidylcholine synthesis via increased choline uptake.
Nakamura T, Fujiwara R, Ishiguro N, Oyabu M, Nakanishi T, Shirasaka Y, Maeda T, Tamai I. | 11/13/2010 |
| The presence of CTL1 protein in rat and human CNS regions, where it is found in neuronal, glial and endothelial cells, suggests that malfunction of this transporter could have important implications in nervous system development and repair. | Detection of choline transporter-like 1 protein CTL1 in neuroblastoma x glioma cells and in the CNS, and its role in choline uptake.
Machová E, O'Regan S, Newcombe J, Meunier FM, Prentice J, Dove R, Lisá V, Dolezal V. | 01/21/2010 |
| SLC44A1 mRNA and protein expression were down-regulated during choline deficiency. | The solute carrier 44A1 is a mitochondrial protein and mediates choline transport.
Michel V, Bakovic M. | 01/21/2010 |
| characterization the 5'-flanking region of the human (h)CTL1 gene and some of the possible mechanisms of its regulation, including promoter activity, splicing, and expression | Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1.
Yuan Z, Tie A, Tarnopolsky M, Bakovic M. | 01/21/2010 |
| This study provides the first example of CHT1 expression in neurons which do not use acetylcholine as neurotransmitter. | Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia.
Lecomte MJ, De Gois S, Guerci A, Ravassard P, Faucon Biguet N, Mallet J, Berrard S. | 01/21/2010 |
| Data suggest that an impaired choline transporter-like protein-1 trafficking is the key contributing factor to reduced choline uptake, subsequent to the PMA-induced THP-1 differentiation to macrophages. | Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages.
Fullerton MD, Wagner L, Yuan Z, Bakovic M. | 01/21/2010 |