| Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis. | Alpha-2-macroglobulin is involved in the occurrence of early-onset pre-eclampsia via its negative impact on uterine spiral artery remodeling and placental angiogenesis.
Wang J, Zhang P, Liu M, Huang Z, Yang X, Ding Y, Liu J, Cheng X, Xu S, He M, Zhang F, Wang G, Li R, Yang X., Free PMC Article | 03/17/2023 |
| Gastric contents-induced acute lung injury elicits a liver acute phase response characterized by increased mRNA expression of alpha 2 macroglobulin and alpha1-antitrypsin. | Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection.
Ayala P, Meneses M, Olmos P, Montalva R, Droguett K, Ríos M, Borzone G., Free PMC Article | 12/2/2017 |
| elevated serum level correlated to glucocorticoid treatment and may represent a form of reparative response to glucocorticoid-associated damage of bone | Substrain-specific differences in bone parameters, alpha-2-macroglobulin circulating levels, and osteonecrosis incidence in a rat model.
Carli AV, Harvey EJ, Azeddine B, Gao C, Li Y, Li A, Sayegh M, Wang H, Nahal A, Michel RP, Henderson JE, Séguin C. | 10/7/2017 |
| Differentiation of protein species of alpha-2u-globulin according to database entries | Differentiation of protein species of alpha-2u-globulin according to database entries: A half-theoretical approach.
Aksu S, Tanrikulu F. | 12/17/2016 |
| Peak serum levels of alpha(2)-macroglobulin and alpha(1)-acid glycoprotein injected at 0.05 mL/rat were significantly lower than those at 0.2 or 0.4 mL/rat. No significant differences were observed for peak serum levels at 0.2 and 0.4 mL/rat. | Relationship between production of acute-phase proteins and strength of inflammatory stimulation in rats.
Kuribayashi T, Tomizawa M, Seita T, Tagata K, Yamamoto S., Free PMC Article | 10/22/2011 |
| alpha(2)M induces protein factors whose interplay underlies radioprotection | Administration of rat acute-phase protein α(2)-macroglobulin before total-body irradiation initiates cytoprotective mechanisms in the liver.
Bogojević D, Poznanović G, Grdović N, Grigorov I, Vidaković M, Dinić S, Mihailović M. | 10/1/2011 |
| alpha2-macroglobulin is neurotoxic by inhibiting neuroprotective activity of nerve growth factor via TrkA receptors. | During glaucoma, alpha2-macroglobulin accumulates in aqueous humor and binds to nerve growth factor, neutralizing neuroprotection.
Bai Y, Sivori D, Woo SB, Neet KE, Lerner SF, Saragovi HU. | 09/17/2011 |
| Role of cardiac isoform of alpha-2 macroglobulin in diabetic myocardium. | Role of cardiac isoform of alpha-2 macroglobulin in diabetic myocardium.
Soman S, Manju CS, Rauf AA, Indira M, Rajamanickam C. | 07/16/2011 |
| Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma | Alpha2-macroglobulin is a mediator of retinal ganglion cell death in glaucoma.
Shi Z, Rudzinski M, Meerovitch K, Lebrun-Julien F, Birman E, Di Polo A, Saragovi HU., Free PMC Article | 01/21/2010 |
| involvement of STAT5b in alpha(2)-macroglobulin gene expression during development | Nuclear localization and binding affinity of STAT5b for the alpha(2)-macroglobulin gene promoter during rat liver development and the acute-phase response.
Mihailović M, Dinić S, Bogojević D, Ivanović-Matić S, Uskoković A, Arambasić J, Grigorov I, Grdović N, Vidaković M, Martinović V, Petrović M, Poznanović G. | 01/21/2010 |
| DNA binding activity on the rat alpha2-macroglobulin gene promoter is regulated in an acute-phase dependent manner | DNA binding activity of C/EBPbeta and C/EBPdelta for the rat alpha2-macroglobulin gene promoter is regulated in an acute-phase dependent manner.
Milosavljevic TS, Petrovic MV, Cvetkovic ID, Grigorov II. | 01/21/2010 |
| alpha 2 macroglobulin has a role in development of rat hepatocellular preneoplastic and neoplastic lesions | alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers.
Sukata T, Uwagawa S, Ozaki K, Sumida K, Kikuchi K, Kushida M, Saito K, Morimura K, Oeda K, Okuno Y, Mikami N, Fukushima S., Free PMC Article | 01/21/2010 |
| phosphorylation of LRP by PKCalpha modulates the endocytic and signaling function of LRP by modifying its association with adaptor proteins | Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.
Ranganathan S, Liu CX, Migliorini MM, Von Arnim CA, Peltan ID, Mikhailenko I, Hyman BT, Strickland DK. | 01/21/2010 |
| Alpha 2 macroglobulin is directly responsible for causation of anemia in the hosts of Yoshida ascites sarcoma by affecting erythrocyte deformability. | Cancer-related anemia in a rat model: alpha2-macroglobulin from Yoshida sarcoma shortens erythrocyte survival.
Bhanushali AA, Raghunathan R, Kalraiya RD, Mehta NG. | 01/21/2010 |
| role in reducing calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in hippocampal neurons | alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons.
Qiu Z, Strickland DK, Hyman BT, Rebeck GW. | 01/21/2010 |
| cardiac hypertrophy may be induced by the presence of alpha-2 Macroglobulin, cardiac isoform | Direct injection and expression in vivo of full-length cDNA of the cardiac isoform of alpha-2 macroglobulin induces cardiac hypertrophy in the rat heart.
Rajan S, Radhakrishnan J, Rajamanickam C. | 01/21/2010 |
| bone morphogenetic protein 1 is inhibited by native and altered forms of alpha2-macroglobulin | Inhibition of bone morphogenetic protein 1 by native and altered forms of alpha2-macroglobulin.
Zhang Y, Ge G, Greenspan DS. | 01/21/2010 |
| Data suggest that alpha(2)macroglobulin gene expression is driven by developmental- and acute-phase-related mechanisms that rely on STAT3/NF-kappaB interplay. | STAT3/NFkappaB interplay in the regulation of alpha2-macroglobulin gene expression during rat liver development and the acute phase response.
Uskoković A, Dinić S, Mihailović M, Grigorov I, Ivanović-Matić S, Bogojević D, Grdović N, Arambasić J, Vidaković M, Martinović V, Petrović M, Poznanović G. | 01/21/2010 |