| The role of histamine H1 receptor in the anterior cingulate cortex on nociception level following acute restraint stress in male rats. | The role of histamine H(1) receptor in the anterior cingulate cortex on nociception level following acute restraint stress in male rats.
Daniali R, Zeraati F, Mohammadi M, Haddadi R., Free PMC Article | 03/18/2024 |
| Increased Nuclear FOXP2 Is Related to Reduced Neural Stem Cell Number and Increased Neurogenesis in the Dorsal Telencephalon of Embryos of Diabetic Rats through Histamine H1 Receptors. | Increased Nuclear FOXP2 Is Related to Reduced Neural Stem Cell Number and Increased Neurogenesis in the Dorsal Telencephalon of Embryos of Diabetic Rats through Histamine H(1) Receptors.
De la Merced-García DS, Sánchez-Barrera Á, Hernández-Yonca J, Mancilla I, García-López G, Díaz NF, Terrazas LI, Molina-Hernández A., Free PMC Article | 02/16/2023 |
| P2X4 Receptors Mediate Ca(2+) Release from Lysosomes in Response to Stimulation of P2X7 and H1 Histamine Receptors. | P2X4 Receptors Mediate Ca(2+) Release from Lysosomes in Response to Stimulation of P2X7 and H(1) Histamine Receptors.
Tan SL, Barri M, Atakpa-Adaji P, Taylor CW, St John Smith E, Murrell-Lagnado RD., Free PMC Article | 10/30/2021 |
| the histaminergic afferent inputs in the striatum may modulate both dopamine D1 and D2 receptor-expressing medium spiny projection neurons by activation of postsynaptic histamine H1 and H2 receptors. | Histamine Excites Striatal Dopamine D1 and D2 Receptor-Expressing Neurons via Postsynaptic H1 and H2 Receptors.
Zhuang QX, Xu HT, Lu XJ, Li B, Yung WH, Wang JJ, Zhu JN. | 12/22/2018 |
| Data (including data from studies in knockout mice) suggest that sleep-promoting effect of dietary supplement rice bran is dependent on Hrh1 antagonism; rice bran fully inhibits Hrh1 agonist-induced increase in action potential frequency in tuberomammillary nucleus neurons. | A novel neurological function of rice bran: a standardized rice bran supplement promotes non-rapid eye movement sleep in mice through histamine H(1) receptors.
Um MY, Kim S, Jin YH, Yoon M, Yang H, Lee J, Jung J, Urade Y, Huang ZL, Kwon S, Cho S. | 06/30/2018 |
| findings indicate that histamine H1, H2, and H3 receptors are present in rat olfactory epithelium and may play a physiological role in olfactory transmission. | Expression and localization of histamine H(1), H(2), and H(3) receptors in rat olfactory epithelium.
Yu C, Li L, Xia Q, Tang Y. | 10/28/2017 |
| This study demonstrates that AITC-induced nociception in vivo depends on TRPA1 and is decreased by the blockade of the NK1 receptor for SP, the H1 receptor for histamine and the 5-HT1A and 3 receptors for 5-HT | TRPA1, substance P, histamine and 5-hydroxytryptamine interact in an interdependent way to induce nociception.
Fischer L, Lavoranti MI, de Oliveira Borges M, Miksza AF, Sardi NF, Martynhak BJ, Tambeli CH, Parada CA. | 07/29/2017 |
| An H1 receptor blocker did not affect exercise-induced improvement in learning and memory in rats, so these receptors may not play a role in this process. | The role of the central histaminergic receptors in the exercise-induced improvements of the spatial learning and memory in rats.
Taati M, Moghaddasi M, Esmaeili M, Pourkhodadad S, Nayebzadeh H. | 07/25/2015 |
| Isolated rat mesenteric collecting lymphatics were treated with 1- to 100-muM histamine. Pharmacologic blockade of either H1 or H2 histamine receptors significantly inhibited the response to histamine. | Involvement of H1 and H2 receptors and soluble guanylate cyclase in histamine-induced relaxation of rat mesenteric collecting lymphatics.
Kurtz KH, Moor AN, Souza-Smith FM, Breslin JW., Free PMC Article | 06/20/2015 |
| Activation of H1R was required dopaminergic lineage during ventral midbrain development. | Histamine impairs midbrain dopaminergic development in vivo by activating histamine type 1 receptors.
Escobedo-Avila I, Vargas-Romero F, Molina-Hernández A, López-González R, Cortés D, De Carlos JA, Velasco I., Free PMC Article | 04/18/2015 |
| Na+-Ca2+ exchangers coupled to H1 receptors and hyperpolarization-activated cyclic nucleotide-gated channels linked to H2 receptors co-mediate the strong postsynaptic excitatory action of histamine on al vestibular nucleus neurons | Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats.
Zhang XY, Yu L, Zhuang QX, Peng SY, Zhu JN, Wang JJ., Free PMC Article | 09/6/2014 |
| These results show that histamine, by activating H(1)R, has a neurogenic effect in clonal conditions | Histamine up-regulates fibroblast growth factor receptor 1 and increases FOXP2 neurons in cultured neural precursors by histamine type 1 receptor activation: conceivable role of histamine in neurogenesis during cortical development in vivo.
Molina-Hernández A, Rodríguez-Martínez G, Escobedo-Ávila I, Velasco I., Free PMC Article | 08/31/2013 |
| Histamine within the nucleus tractus solitarii may play a role in regulating cardiovascular homeostasis via activation of H1 receptors. | Histamine receptor H1 in the nucleus tractus solitarii regulates arterial pressure and heart rate in rats.
Bhuiyan ME, Waki H, Gouraud SS, Takagishi M, Kohsaka A, Maeda M. | 10/1/2011 |
| at the level of the hippocampus, histamine through its H1 and H2 receptors, mediates orofacial region pain | Interaction between histamine and morphine at the level of the hippocampus in the formalin-induced orofacial pain in rats.
Tamaddonfard E, Erfanparast A, Farshid AA, Khalilzadeh E. | 09/17/2011 |
| H1 receptors play an excitatory role in the modulation of the discharge activities of the inspiratory neurons in neonatal rat brainstem slices. | [Histamine H1 receptors modulate the discharge activities of inspiratory neurons in the medial region of neonatal rat nucleus retrofacialis ex vivo].
Qian ZB, Qi Y, Wu ZH. | 08/13/2011 |
| Based on its ability to reverse amphetamine-induced PPI deficits, blockade of histamine H(1) receptors seems to contribute to the therapeutic effect of the antipsychotic clozapine. | PPI deficit induced by amphetamine is attenuated by the histamine H1 antagonist pyrilamine, but is exacerbated by the serotonin 5-HT2 antagonist ketanserin.
Larrauri JA, Levin ED. | 02/26/2011 |
| Studies using various antagonists indicate hippocampal Hrh1 plays an important role in encoding, retention, and retrieval processes of spatial working memory. | Effects of histamine H(1) receptor antagonists on delayed spatial win-shift task in rats.
Okada A, Kato A, Kamei C. | 05/31/2010 |
| These results suggest that chewing-induced histamine release in the hippocampus and the subsequent H1 receptor activation may be essential to rescue stress-suppressed synaptic plasticity. | Chewing rescues stress-suppressed hippocampal long-term potentiation via activation of histamine H1 receptor.
Ono Y, Kataoka T, Miyake S, Sasaguri K, Sato S, Onozuka M. | 01/21/2010 |
| The expression of H1 receptor mRNA was up-regulated in the hypothalamus and brainstem, but not in the cerebral cortex after 2 G hypergravity load in rats. | Effects of hypergravity on histamine H1 receptor mRNA expression in hypothalamus and brainstem of rats: implications for development of motion sickness.
Sato G, Uno A, Horii A, Umehara H, Kitamura Y, Sekine K, Tamura K, Fukui H, Takeda N. | 01/21/2010 |
| Data show that cetirizine, a histamine H1 receptor antagonist, decreases the first stage of orthodontic tooth movement in rats. | Cetirizine, a histamine H1 receptor antagonist, decreases the first stage of orthodontic tooth movement in rats.
Kriznar I, Sprogar S, Drevensek M, Vaupotic T, Drevensek G. | 01/21/2010 |
| Data show that the synergistic effect of histamine and IL-6 on NGF secretion from cultured astrocytes is evoked by histamine stimulation of IL-6 secretion via a H1-receptor-PKC-MAPK signalling pathway. | The synergistic effect of histamine and IL-6 on NGF secretion from cultured astrocytes is evoked by histamine stimulation of IL-6 secretion via H1-receptor-PKC-MAPK signalling pathway.
Ales K, Wraber B, Lipnik-Stangelj M. | 01/21/2010 |
| Results suggest that hippocampal H1 receptors play an important role in working memory processes on radial maze performance and the decrease in hippocampal theta power is associated with the working memory deficit induced by the blocking of H1 receptors. | Role of hippocampal H1 receptors in radial maze performance and hippocampal theta activity in rats.
Masuoka T, Kamei C. | 01/21/2010 |
| Activation of H1-receptors in vasopressinergic neurons results in downstream activation of NO synthase, which then mediates the H1-receptor effects. | Histamine H1-receptor modulation of inter-neuronal coupling among vasopressinergic neurons depends on nitric oxide synthase activation.
Yang QZ, Hatton GI. | 01/21/2010 |
| histamine H(1)-receptor and PKC are involved in the signal transduction pathway, responsible for histamine-stimulated NGF secretion from cultured astrocytes | Activation of histamine H1-receptor enhances neurotrophic factor secretion from cultured astrocytes.
Lipnik-Stangelj M, Carman-Krzan M. | 01/21/2010 |
| Processing of proprioceptive information at the level of the mesencephalic trigeminal neurons is controlled via histamine H1 and H3 receptors through different postsynaptic mechanisms. | Selective expression of histamine receptors in rat mesencephalic trigeminal neurons.
Lazarov NE, Gratzl M. | 01/21/2010 |