| Association of Saitohin gene rs62063857 polymorphism with dry type age-related macular degeneration. | Association of Saitohin gene rs62063857 polymorphism with dry type age-related macular degeneration.
Bonyadi M, Ahmadieh H, Jabbarpoor Bonyadi MH, Shahpasand K, Suri F, Nasrabadi N, Yaseri M, Kheiri B, Soheilian M. | 06/26/2021 |
| Saitohin Q7R polymorphism is associated with late-onset Alzheimer's disease susceptibility among caucasian populations. (Meta-analysis) | Saitohin Q7R polymorphism is associated with late-onset Alzheimer's disease susceptibility among caucasian populations: a meta-analysis.
Huang R, Tian S, Cai R, Sun J, Xia W, Dong X, Shen Y, Wang S., Free PMC Article | 04/21/2018 |
| Results showed a significant interaction effect of COMT and STH polymorphisms on cognitive performances, strengthening the involvement of STH in cognitive impairments, especially in the domains commonly impaired in schizophrenia | COMT and STH polymorphisms interaction on cognition in schizophrenia.
Bosia M, Pigoni A, Pirovano A, Lorenzi C, Spangaro M, Buonocore M, Bechi M, Cocchi F, Guglielmino C, Bramanti P, Smeraldi E, Cavallaro R. | 01/2/2016 |
| The rs6203857 polymorphism of the saitohin gene is a genetic risk factor for Parkinson's disease. | Association of rs62063857 variant of the saitohin gene with Parkinson's disease.
Sonmez E, Ozel MD, Islek EE, Sazci A, Idrisoglu HA. | 09/26/2015 |
| results of this meta-analysis suggested that MAPT_238bp/STH Q7R polymorphisms might modulate the risk of Parkinson's disease susceptibility | Association of microtubule associated protein tau/Saitohin (MAPT/STH) MAPT_238bp/STH Q7R polymorphisms and Parkinson's disease: A meta-analysis.
Lu SS, Gong FF, Feng F, Hu CY, Qian ZZ, Wu YL, Yang HY, Sun YH. | 08/29/2015 |
| These results suggest a possible contribution of STH gene products on the heterogeneity of core frontal executive functions deterioration in schizophrenia | Saitohin polymorphism and executive dysfunction in schizophrenia.
Bosia M, Buonocore M, Guglielmino C, Pirovano A, Lorenzi C, Marcone A, Bramanti P, Cappa SF, Aguglia E, Smeraldi E, Cavallaro R. | 04/20/2013 |
| Single polymorphisms within the saitohin gene were associated with increased cognitive impairment and functional dependence persons with moderate-to-advanced Alzheimer disease. | Saitohin and APOE polymorphisms influence cognition and function in persons with advanced Alzheimer Disease.
Schutte DL, Reed D, Decrane S, Ersig AL. | 03/3/2012 |
| effect of Saitohin on Abl-mediated phosphorylation appears to be allele-specific, providing evidence for a new cellular function for STH | Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation.
Wang Y, Gao L, Conrad CG, Andreadis A., Free PMC Article | 02/25/2012 |
| STH polymorphisms play a possibly shared role with those of serotinin transporter 5-HTTLPR gene as a susceptibility factor for Alzheimer's disease and frontotemperal lobar dementia. | Serotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: preliminary findings.
Lorenzi C, Marcone A, Pirovano A, Marino E, Cordici F, Cerami C, Delmonte D, Cappa SF, Bramanti P, Smeraldi E, Lorenzi C, Marcone A, Pirovano A, Marino E, Cordici F, Cerami C, Delmonte D, Cappa SF, Bramanti P, Smeraldi E. | 10/1/2011 |
| The Saitohin Q7R polymorphism is unlikely to contribute significantly to Alzheimer's disease susceptibility of the Han population in south China. | The Q7R polymorphism in the saitohin gene is rare in a southern Chinese population.
Lin K, Tang M, Guo Y, Han H, Lin Y, Ma C, Lin K, Tang M, Guo Y, Han H, Lin Y, Ma C. | 01/21/2010 |
| Homozygous Q/Q of STH Q7R polymorphism was the only one genotype found in either LOAD group or controls. No R allele was detected in LOAD and control groups. | Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease.
Wang B, Zhou S, Yang Z, Xie YC, Wang J, Zhang P, Lv Z, Zheng C, Ma X, Wang B, Zhou S, Yang Z, Xie YC, Wang J, Zhang P, Lv Z, Zheng C, Ma X. | 01/21/2010 |
| Q allele of STH gene is over-represented in a tested group of patients with Huntington disease and might be considered a risk factor for HD like diseases. | HD phenocopies--possible role of Saitohin gene.
Janković N, Kecmanović M, Dimitrijević R, Keckarević Marković M, Dobricić V, Keckarević D, Savić Pavicević D, Romac S, Janković N, Kecmanović M, Dimitrijević R, Keckarević Marković M, Dobricić V, Keckarević D, Savić Pavicević D, Romac S. | 01/21/2010 |
| Observational study of genotype prevalence. (HuGE Navigator) | HD phenocopies--possible role of Saitohin gene.
Janković N, Kecmanović M, Dimitrijević R, Keckarević Marković M, Dobricić V, Keckarević D, Savić Pavicević D, Romac S, Janković N, Kecmanović M, Dimitrijević R, Keckarević Marković M, Dobricić V, Keckarević D, Savić Pavicević D, Romac S. | 04/3/2008 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesThe Q7R polymorphism in the saitohin gene is rare in a southern Chinese population.
Lin K, Tang M, Guo Y, Han H, Lin Y, Ma C, Lin K, Tang M, Guo Y, Han H, Lin Y, Ma C. Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study.
Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, Goldwurm S, Pezzoli G, Singer C, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Laramie JM, DeStefano AL, Litvan I, Nicholson G, Corbett A, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Sherman S, Al-hinti J, Drasby E, Nance M, Moller AT, Ostergaard K, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.
Johansson A, Zetterberg H, Håkansson A, Nissbrandt H, Blennow K, Johansson A, Zetterberg H, Håkansson A, Nissbrandt H, Blennow K. Variation at APOE and STH loci and Alzheimer's disease.
Zuo L, van Dyck CH, Luo X, Kranzler HR, Yang BZ, Gelernter J. | 03/13/2008 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | See all PubMed (4) articlesSerotonin transporter and saitohin genes in risk of Alzheimer's disease and frontotemporal lobar dementia: preliminary findings.
Lorenzi C, Marcone A, Pirovano A, Marino E, Cordici F, Cerami C, Delmonte D, Cappa SF, Bramanti P, Smeraldi E, Lorenzi C, Marcone A, Pirovano A, Marino E, Cordici F, Cerami C, Delmonte D, Cappa SF, Bramanti P, Smeraldi E. Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease.
Wang B, Zhou S, Yang Z, Xie YC, Wang J, Zhang P, Lv Z, Zheng C, Ma X, Wang B, Zhou S, Yang Z, Xie YC, Wang J, Zhang P, Lv Z, Zheng C, Ma X. Cluster analysis of risk factor genetic polymorphisms in Alzheimer's disease.
Randall CN, Strasburger D, Prozonic J, Morris SN, Winkie AD, Parker GR, Cheng D, Fennell EM, Lanham I, Vakil N, Huang J, Cathcart H, Huang R, Poduslo SE. Alzheimer disease risk associated with APOE4 is modified by STH gene polymorphism.
Seripa D, Matera MG, D'Andrea RP, Gravina C, Masullo C, Daniele A, Bizzarro A, Rinaldi M, Antuono P, Wekstein DR, Dal Forno G, Fazio VM. | 03/13/2008 |
| The saitohin Q allele, a novel determinant of tau H1 haplotypes, may represent a causative factor involved in the determinism of several tauopathies, e.g., frontotemporal dementia. | Is the saitohin gene involved in neurodegenerative diseases?
Verpillat P, Ricard S, Hannequin D, Dubois B, Bou J, Camuzat A, Pradier L, Frebourg T, Brice A, Clerget-Darpoux F, Deleuze JF, Campion D, French Study Group on Alzheimer's Disease and Frontotemporal Dementia. | 01/21/2010 |
| We found no evidence that could support a major pathogenic role of STH and TAU haplotype in AD, FTD or PD. | TAU haplotype and the Saitohin Q7R gene polymorphism do not influence CSF Tau in Alzheimer's disease and are not associated with frontotemporal dementia or Parkinson's disease.
Johansson A, Zetterberg H, Håkansson A, Nissbrandt H, Blennow K, Johansson A, Zetterberg H, Håkansson A, Nissbrandt H, Blennow K. | 01/21/2010 |
| The R allele of STH is associated with the H2 haplotype of tau; no correlation is found between R allele frequency and Alzheimer's or Parkinson's disease. | Strong association between Saitohin gene polymorphism and tau haplotype in the Polish population.
Pepłońska B, Zekanowski C, Religa D, Czyzewski K, Styczyńska M, Pfeffer A, Gabryelewicz T, Gołebiowski M, Luczywek E, Wasiak B, Barczak A, Chodakowska M, Barcikowska M, Kuźnicki J. | 01/21/2010 |
| Saitohin interacts with peroxiredoxin 6, a unique member of that family that is bifunctional and the levels of which increase in Pick disease. | Saitohin, which is nested in the tau locus and confers allele-specific susceptibility to several neurodegenerative diseases, interacts with peroxiredoxin 6.
Gao L, Tse SW, Conrad C, Andreadis A. | 01/21/2010 |
| Increased risk of Alzheimer's disease associated with the STH RR genotype is limited to late-onset Alzheimer's disease. | Age-dependent association between the Q7R polymorphism in the Saitohin gene and sporadic Alzheimer's disease.
Combarros O, Rodero L, Infante J, Palacio E, Llorca J, Fernández-Viadero C, Peña N, Berciano J. | 01/21/2010 |
| At the STH gene only a common polymorphic change was found. | Mutation screening of the MAPT and STH genes in Polish patients with clinically diagnosed frontotemporal dementia.
Zekanowski C, Pepłońska B, Styczyńska M, Gustaw K, Kuźnicki J, Barcikowska M. | 01/21/2010 |
| a gene within an intron of the tau gene; Q7R polymorphism appears to be over-represented in the homozygous state in late onset Alzheimer's disease subjects | A polymorphic gene nested within an intron of the tau gene: implications for Alzheimer's disease.
Conrad C, Vianna C, Freeman M, Davies P., Free PMC Article | 01/21/2010 |