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    FTL ferritin light chain [ Homo sapiens (human) ]

    Gene ID: 2512, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain.

    Microglial CD68 and L-ferritin upregulation in response to phosphorylated-TDP-43 pathology in the amyotrophic lateral sclerosis brain.
    Swanson MEV, Mrkela M, Murray HC, Cao MC, Turner C, Curtis MA, Faull RLM, Walker AK, Scotter EL., Free PMC Article

    08/25/2023
    Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling.

    Ferritin light chain deficiency-induced ferroptosis is involved in preeclampsia pathophysiology by disturbing uterine spiral artery remodelling.
    Yang X, Ding Y, Sun L, Shi M, Zhang P, Huang Z, Wang J, He A, Wang J, Wei J, Liu M, Liu J, Wang G, Yang X, Li R., Free PMC Article

    12/17/2022
    Ferritin L-subunit gene mutation and hereditary hyperferritinaemia cataract syndrome (HHCS): a case report and literature review.

    Ferritin L-subunit gene mutation and hereditary hyperferritinaemia cataract syndrome (HHCS): a case report and literature review.
    Yang Y, Lin T, Kuang P, Chen X.

    12/18/2021
    CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles.

    CD63 is regulated by iron via the IRE-IRP system and is important for ferritin secretion by extracellular vesicles.
    Yanatori I, Richardson DR, Dhekne HS, Toyokuni S, Kishi F., Free PMC Article

    12/11/2021
    Increasing ferritin predicts early death in adult hemophagocytic lymphohistiocytosis.

    Increasing ferritin predicts early death in adult hemophagocytic lymphohistiocytosis.
    Abou Shaar R, Eby CS, van Dorp S, de Witte T, Otrock ZK.

    12/4/2021
    Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells.

    Cigarette smoke extract and heated tobacco products promote ferritin cleavage and iron accumulation in human corneal epithelial cells.
    Otsu W, Ishida K, Chinen N, Nakamura S, Shimazawa M, Tsusaki H, Hara H., Free PMC Article

    11/22/2021
    Longitudinal CSF Iron Pathway Proteins in Posthemorrhagic Hydrocephalus: Associations with Ventricle Size and Neurodevelopmental Outcomes.

    Longitudinal CSF Iron Pathway Proteins in Posthemorrhagic Hydrocephalus: Associations with Ventricle Size and Neurodevelopmental Outcomes.
    Strahle JM, Mahaney KB, Morales DM, Buddhala C, Shannon CN, Wellons JC 3rd, Kulkarni AV, Jensen H, Reeder RW, Holubkov R, Riva-Cambrin JK, Whitehead WE, Rozzelle CJ, Tamber M, Pollack IF, Naftel RP, Kestle JRW, Limbrick DD Jr, Hydrocephalus Clinical Research Network., Free PMC Article

    11/13/2021
    Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity.

    Ferritin as a key risk factor for nonalcoholic fatty liver disease in children with obesity.
    Zhang J, Cao J, Xu H, Dong G, Huang K, Wu W, Ye J, Fu J., Free PMC Article

    10/30/2021
    Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC.

    Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC.
    Fan K, Lu C, Shu G, Lv XL, Qiao E, Zhang N, Chen M, Song J, Wu F, Zhao Z, Xu X, Xu M, Chen C, Yang W, Sun J, Du Y, Ji J., Free PMC Article

    10/16/2021
    A unique mutation in the L ferritin coding sequence associated with low serum ferritin level in the presence of normal values of other iron parameters.

    A unique mutation in the L ferritin coding sequence associated with low serum ferritin level in the presence of normal values of other iron parameters.
    Ciftciler R, Yılmaz E, Buyukasik Y.

    08/21/2021
    Extracellular vesicles from thalassemia patients carry iron-containing ferritin and hemichrome that promote cardiac cell proliferation.

    Extracellular vesicles from thalassemia patients carry iron-containing ferritin and hemichrome that promote cardiac cell proliferation.
    Atipimonpat A, Siwaponanan P, Khuhapinant A, Svasti S, Sukapirom K, Khowawisetsut L, Pattanapanyasat K.

    07/31/2021
    Comprehensive analysis of ferritin subunits expression and positive correlations with tumor-associated macrophages and T regulatory cells infiltration in most solid tumors.

    Comprehensive analysis of ferritin subunits expression and positive correlations with tumor-associated macrophages and T regulatory cells infiltration in most solid tumors.
    Hu ZW, Chen L, Ma RQ, Wei FQ, Wen YH, Zeng XL, Sun W, Wen WP., Free PMC Article

    07/31/2021
    A 3'-truncating FTL mutation associated with hypoferritinemia without neuroferritinopathy.

    A 3'-truncating FTL mutation associated with hypoferritinemia without neuroferritinopathy.
    Turner S, Dress C, Misra VK.

    07/10/2021
    Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.

    Serum Ferritin Correlates With Liver Fat in Male Adolescents With Obesity.
    Mörwald K, Aigner E, Bergsten P, Brunner SM, Forslund A, Kullberg J, Ahlström H, Manell H, Roomp K, Schütz S, Zsoldos F, Renner W, Furthner D, Maruszczak K, Zandanell S, Weghuber D, Mangge H., Free PMC Article

    05/29/2021
    Antibodies specific to ferritin light chain polypeptide are frequently detected in patients with immunerelated pancytopenia.

    Antibodies specific to ferritin light chain polypeptide are frequently detected in patients with immune‑related pancytopenia.
    Hao S, Zhang Y, Hua L, Xie N, Xiao N, Wang H, Fu R, Shao Z., Free PMC Article

    04/24/2021
    Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma.

    Hypoxia induced ferritin light chain (FTL) promoted epithelia mesenchymal transition and chemoresistance of glioma.
    Liu J, Gao L, Zhan N, Xu P, Yang J, Yuan F, Xu Y, Cai Q, Geng R, Chen Q., Free PMC Article

    04/3/2021
    Thermodynamic and Kinetic Studies of the Interaction of Nuclear Receptor Coactivator-4 (NCOA4) with Human Ferritin.

    Thermodynamic and Kinetic Studies of the Interaction of Nuclear Receptor Coactivator-4 (NCOA4) with Human Ferritin.
    Srivastava AK, Flint N, Kreckel H, Gryzik M, Poli M, Arosio P, Bou-Abdallah F.

    03/13/2021
    Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases.

    Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases.
    Kappert K, Jahić A, Tauber R.

    01/2/2021
    Ferritin in glioblastoma.

    Ferritin in glioblastoma.
    Jaksch-Bogensperger H, Spiegl-Kreinecker S, Arosio P, Eckl P, Golaszewski S, Ebner Y, Al-Schameri R, Strasser P, Weis S, Bresgen N., Free PMC Article

    12/26/2020
    Hepcidin and ferritin levels in restless legs syndrome: a case-control study.

    Hepcidin and ferritin levels in restless legs syndrome: a case-control study.
    Chenini S, Delaby C, Rassu AL, Barateau L, Vialaret J, Hirtz C, Dupuy AM, Lehmann S, Jaussent I, Dauvilliers Y., Free PMC Article

    12/12/2020
    Ferritin Light Chain (FTL) competes with long noncoding RNA Linc00467 for miR-133b binding site to regulate chemoresistance and metastasis of colorectal cancer.

    Ferritin Light Chain (FTL) competes with long noncoding RNA Linc00467 for miR-133b binding site to regulate chemoresistance and metastasis of colorectal cancer.
    Li Z, Liu J, Chen H, Zhang Y, Shi H, Huang L, Tao J, Shen R, Wang T.

    10/31/2020
    Low transferrin saturation (TSAT) and high ferritin levels are significant predictors for cerebrovascular and cardiovascular disease and death in maintenance hemodialysis patients.

    Low transferrin saturation (TSAT) and high ferritin levels are significant predictors for cerebrovascular and cardiovascular disease and death in maintenance hemodialysis patients.
    Kuragano T, Joki N, Hase H, Kitamura K, Murata T, Fujimoto S, Fukatsu A, Inoue T, Itakura Y, Nakanishi T., Free PMC Article

    10/24/2020
    Hereditary hyperferritinaemia-cataract syndrome (HHCS) - an underestimated condition: ferritin light chain variant spectrum in German families.

    Hereditary hyperferritinaemia-cataract syndrome (HHCS) - an underestimated condition: ferritin light chain variant spectrum in German families.
    Volkmann M, Richter R, Herrmann T, Hentze S, Hör M, Hasche H, Selle B, Stremmel W, Gehrke SG.

    09/19/2020
    Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort.

    Ferritin and C-reactive protein are predictive biomarkers of mortality and macrophage activation syndrome in adult onset Still's disease. Analysis of the multicentre Gruppo Italiano di Ricerca in Reumatologia Clinica e Sperimentale (GIRRCS) cohort.
    Di Benedetto P, Cipriani P, Iacono D, Pantano I, Caso F, Emmi G, Grembiale RD, Cantatore FP, Atzeni F, Perosa F, Scarpa R, Guggino G, Ciccia F, Giacomelli R, Ruscitti P., Free PMC Article

    09/12/2020
    possible associations between ferritin, iron, and transferrin saturation (TSAT) and lung function to clarify the role of iron-related parameters in healthy men, are reported.

    Decreased lung function is associated with elevated ferritin but not iron or transferrin saturation in 42,927 healthy Korean men: A cross-sectional study.
    Lee J, Park HK, Kwon MJ, Ham SY, Kim JM, Lim SY, Song JU., Free PMC Article

    07/11/2020
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