Role of the JAK2/STAT3 pathway in angiotensin II-induced enhanced expression of Gialpha proteins and hyperproliferation of aortic vascular smooth muscle cells. | Role of the JAK2/STAT3 pathway in angiotensin II-induced enhanced expression of Giα proteins and hyperproliferation of aortic vascular smooth muscle cells. Hossain E, Li Y, Anand-Srivastava MB. | 07/26/2024 |
STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells. | STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells. Zhang H, Chen L, Li J, Sun J, Zhao Q, Wang S, Li G., Free PMC Article | 06/28/2024 |
Daucosterol regulates JAK2-STAT3 signaling pathway to promote megakaryocyte differentiation. | Daucosterol regulates JAK2-STAT3 signaling pathway to promote megakaryocyte differentiation. Zhang Z, Shang G, Lu Z, Hu J, Liu H, Lu T, Lu X. | 06/12/2024 |
Hypoxic-preconditioned mesenchymal stem cell-derived small extracellular vesicles promote the recovery of spinal cord injury by affecting the phenotype of astrocytes through the miR-21/JAK2/STAT3 pathway. | Hypoxic-preconditioned mesenchymal stem cell-derived small extracellular vesicles promote the recovery of spinal cord injury by affecting the phenotype of astrocytes through the miR-21/JAK2/STAT3 pathway. Yang Z, Liang Z, Rao J, Xie H, Zhou M, Xu X, Lin Y, Lin F, Wang C, Chen C., Free PMC Article | 03/12/2024 |
IFITM3 mediates inflammation induced myocardial injury through JAK2/STAT3 signaling pathway. | IFITM3 mediates inflammation induced myocardial injury through JAK2/STAT3 signaling pathway. Xiong C, Li B, Song R, Ma Z, Huber SA, Liu W. | 03/1/2024 |
Silencing suppressor of cytokine signaling 3 induces apoptosis and activates the p-STAT3/NF-kappaB pathway in hypoxic cultivated H9c2 cells. | Silencing suppressor of cytokine signaling 3 induces apoptosis and activates the p-STAT3/NF-κB pathway in hypoxic cultivated H9c2 cells. Gu Q, Xiao YB, Wang Y. | 02/14/2024 |
PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction. | PCSK9 regulates myofibroblast transformation through the JAK2/STAT3 pathway to regulate fibrosis after myocardial infarction. Bao H, Wang X, Zhou H, Zhou W, Liao F, Wei F, Yang S, Luo Z, Li W. | 02/2/2024 |
FOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy. | FOXO1 reduces STAT3 activation and causes impaired mitochondrial quality control in diabetic cardiomyopathy. Zhou L, Su W, Wang Y, Zhang Y, Xia Z, Lei S. | 01/11/2024 |
Long noncoding RNA MEG8 induces an imbalance of Th17/Treg cells through the miR-107/STAT3 axis in Henoch-Schonlein purpura rats. | Long noncoding RNA MEG8 induces an imbalance of Th17/Treg cells through the miR-107/STAT3 axis in Henoch-Schonlein purpura rats. Jiang M, Dai J, Jiang C, Pan Y, Ren M, Xing M., Free PMC Article | 12/28/2023 |
Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes. | Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes. Suzuki S, Tanaka S, Kametani Y, Umeda A, Nishinaka K, Egawa K, Okada Y, Obana M, Fujio Y., Free PMC Article | 12/6/2023 |
Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats. | Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats. Li J, Wu G, Li W, Zhou X, Li W, Xu X, Xu K, Cao R, Cui S., Free PMC Article | 12/1/2023 |
The Regulatory Effects of JAK2/STAT3 on Spermatogenesis and the Redox Keap1/Nrf2 Axis in an Animal Model of Testicular Ischemia Reperfusion Injury. | The Regulatory Effects of JAK2/STAT3 on Spermatogenesis and the Redox Keap1/Nrf2 Axis in an Animal Model of Testicular Ischemia Reperfusion Injury. Alnajem A, Al-Maghrebi M., Free PMC Article | 09/29/2023 |
Knocking Down lncRNA HOXA-AS2 Mitigates the Progression of Epilepsy via Regulation of the miR-372-3p/STAT3 Axis. | Knocking Down lncRNA HOXA-AS2 Mitigates the Progression of Epilepsy via Regulation of the miR-372-3p/STAT3 Axis. Song L, Li J, Sun Z. | 09/19/2023 |
Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia-reperfusion by enhancing the interaction between IL-6 and JAK-1/pSTAT3. | Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia-reperfusion by enhancing the interaction between IL-6 and JAK-1/pSTAT3. Cheng M, Liang X, Shi L, Zhang Q, Zhang L, Gong Z, Luo S, Wang X, Zhang X., Free PMC Article | 08/25/2023 |
Reduced expression of Il10, Stat3, Hoxa10, and Itgb3 in the embryo implantation site of rat model with prenatal androgen-induced polycystic ovary syndrome. | Reduced expression of Il10, Stat3, Hoxa10, and Itgb3 in the embryo implantation site of rat model with prenatal androgen-induced polycystic ovary syndrome. Changaei M, Javidan M, Ramezani Tehrani F, Mosaffa N, Noroozzadeh M, Hosseinzadeh R, Rajaei S. | 06/30/2023 |
Inhibition of STAT3 signal pathway recovers postsynaptic plasticity to improve cognitive impairment caused by chronic intermittent hypoxia. | Inhibition of STAT3 signal pathway recovers postsynaptic plasticity to improve cognitive impairment caused by chronic intermittent hypoxia. Wang J, Xu Z, Xu L, Xu P. | 06/1/2023 |
Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats. | Phosphorylation of STAT3 at Tyr705 contributes to TFEB-mediated autophagy-lysosomal pathway dysfunction and leads to ischemic injury in rats. Liu Y, Che X, Yu X, Shang H, Cui P, Fu X, Lu X, Liu Y, Wu C, Yang J., Free PMC Article | 05/22/2023 |
Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse. | Suppressing STAT3 activation impairs bone formation during maxillary expansion and relapse. Xiao X, Chen J, Zhai Q, Xin L, Zheng X, Wang S, Song J., Free PMC Article | 05/11/2023 |
Activating alpha7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway. | Activating α7nAChR helps post-myocardial infarction healing by regulating macrophage polarization via the STAT3 signaling pathway. Niu XH, Liu RH, Lv X, He RL, Lv FZ, Wu SJ, Li XQ, Li L, Lin JF. | 04/28/2023 |
Downregulation of TRIM27 alleviates hypoxic-ischemic encephalopathy through inhibiting inflammation and microglia cell activation by regulating STAT3/HMGB1 axis. | Downregulation of TRIM27 alleviates hypoxic-ischemic encephalopathy through inhibiting inflammation and microglia cell activation by regulating STAT3/HMGB1 axis. Wang C, Zhang P, Li Y, Wang X, Guo L, Li J, Jiao H. | 04/21/2023 |
Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3. | Cyclic tensile force modifies calvarial osteoblast function via the interplay between ERK1/2 and STAT3. Xiao X, Zou S, Chen J., Free PMC Article | 03/14/2023 |
Histone deacetylase 5-induced deficiency of signal transducer and activator of transcription-3 acetylation contributes to spinal astrocytes degeneration in painful diabetic neuropathy. | Histone deacetylase 5-induced deficiency of signal transducer and activator of transcription-3 acetylation contributes to spinal astrocytes degeneration in painful diabetic neuropathy. Fan T, Yu Y, Chen YL, Gu P, Wong S, Xia ZY, Liu JA, Cheung CW. | 02/27/2023 |
Anti-apoptosis effect of recombinant human interleukin-11 in neonatal hypoxic-ischemic rats through activating the IL-11Ralpha/STAT3 signaling pathway. | Anti-apoptosis effect of recombinant human interleukin-11 in neonatal hypoxic-ischemic rats through activating the IL-11Rα/STAT3 signaling pathway. Zuo D, Zheng Q, Xiao M, Wang X, Chen H, Xu J, Zhang Q, Xiong Y, Ye L, Feng Z. | 01/14/2023 |
JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models. | JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models. Ha GH, Kim EJ, Park JS, Kim JE, Nam H, Yeon JY, Lee SH, Lee K, Kim CK, Joo KM., Free PMC Article | 12/17/2022 |
The effect of electroacupuncture on the expression of Sirt1 and STAT3 in hippocampus and amygdala of vascular dementia rats. | The effect of electroacupuncture on the expression of Sirt1 and STAT3 in hippocampus and amygdala of vascular dementia rats. Zhao J, Li W, Wang Y, Jiang Y, Ding C, Li H, Ding J, Wang L. | 11/26/2022 |