| Data show that higher hypoxia inducible factors HIF-1alpha and HIF-1beta transcriptional activity augments lactate production in Sertoli cells. | Participation of HIFs in the regulation of Sertoli cell lactate production.
Galardo MN, Gorga A, Merlo JP, Regueira M, Pellizzari EH, Cigorraga SB, Riera MF, Meroni SB. | 02/4/2017 |
| Loss of suppression on HIF-1beta by miR-103/107 may contribute to excess proliferation of pulmonary arterial smooth muscle cells and vascular remodeling in hypoxic pulmonary hypertension | MicroRNA-103/107 is involved in hypoxia-induced proliferation of pulmonary arterial smooth muscle cells by targeting HIF-1β.
Deng B, Du J, Hu R, Wang AP, Wu WH, Hu CP, Li YJ, Li XH. | 07/16/2016 |
| This study indicated that miR-107 was up-regulated in hypoxia to prevent endothelial progenitor cells differentiation via its target HIF-1beta. [HIF-1beta] | MicroRNA 107 partly inhibits endothelial progenitor cells differentiation via HIF-1β.
Meng S, Cao J, Wang L, Zhou Q, Li Y, Shen C, Zhang X, Wang C., Free PMC Article | 04/6/2013 |
| Aryl hydrocarbon receptor activation may lead to downregulation of Wnt/beta-catenin signaling. | The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors.
Procházková J, Kabátková M, Bryja V, Umannová L, Bernatík O, Kozubík A, Machala M, Vondrácek J. | 12/24/2011 |
| The hypoxia-induced elevation in apelin expression is most likely mediated by HIF, since HIF-activated apelin transcriptional activity is dependent on an intact, putative HIF binding site in the rat apelin promoter. | A possible role for hypoxia-induced apelin expression in enteric cell proliferation.
Han S, Wang G, Qi X, Lee HM, Englander EW, Greeley GH Jr. | 12/9/2011 |
| 4S polycyclic aromatic hydrocarbon receptor (glycine N-methyltransferase) and the aryl hydrocarbon receptor nuclear translocator (hypoxia inducible factor-1beta) interaction in Chinese hamster ovary and rat hepatoma cells: 4S PAH-R/ARNT hetero-oligomers | 4S polycyclic aromatic hydrocarbon receptor (glycine N-methyltransferase) and the aryl hydrocarbon receptor nuclear translocator (hypoxia inducible factor-1β) interaction in Chinese hamster ovary and rat hepatoma cells: 4S PAH-R/ARNT hetero-oligomers?
Sterling KM. | 11/5/2011 |
| beta-cells with reduced ARNT/HIF-1beta expression levels exhibit a 31% reduction in glycolytic flux without significant changes in glucose oxidation or the ATP:ADP ratio | Aryl hydrocarbon receptor nuclear translocator/hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells.
Pillai R, Huypens P, Huang M, Schaefer S, Sheinin T, Wettig SD, Joseph JW., Free PMC Article | 03/5/2011 |
| ARNT expresses K(ATP) channel and by so doing regulates glucose-dependent insulin secretion. | Role of aryl hydrocarbon receptor nuclear translocator in KATP channel-mediated insulin secretion in INS-1 insulinoma cells.
Kim JS, Zheng H, Kim SJ, Park JW, Park KS, Ho WK, Chun YS. | 01/21/2010 |
| bmal1 expression peaked at the the very late phase of the night, but the daily pattern of expression was arrhythmic or phase advanced in TGR rats. | Effect of upregulated renin-angiotensin system on per2 and bmal1 gene expression in brain structures involved in blood pressure control in TGR(mREN-2)27 rats.
Monosíková J, Herichová I, Mravec B, Kiss A, Zeman M. | 01/21/2010 |
| experiments revealed a complex distribution of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator mRNAs and proteins in rat and human testis | Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis.
Schultz R, Suominen J, Värre T, Hakovirta H, Parvinen M, Toppari J, Pelto-Huikko M. | 01/21/2010 |
| Data show that estradiol significantly increased the expression of aryl-hydrocarbon receptor (AhR) nuclear translocator 2 (Arnt2) mRNA in the hypothalamus, but induced no significant changes in the expression of AhR and Arnt1 mRNAs. | Estrogen increases messenger RNA and immunoreactivity of aryl-hydrocarbon receptor nuclear translocator 2 in the rat mediobasal hypothalamus.
Mitsushima D, Funabashi T, Kimura F. | 01/21/2010 |
| Identification of novel splice variants of ARNT. | Identification of novel splice variants of ARNT and ARNT2 in the rat.
Korkalainen M, Tuomisto J, Pohjanvirta R. | 01/21/2010 |