| Synergistic roles of the phospholipase B homolog Plb1 and the cAMP-dependent protein kinase Pka1 in the hypertonic stress response of Schizosaccharomyces pombe. | Synergistic roles of the phospholipase B homolog Plb1 and the cAMP-dependent protein kinase Pka1 in the hypertonic stress response of Schizosaccharomyces pombe.
Matsuo Y, Marcus S, Kawamukai M. | 12/3/2022 |
| Glucose limitation and pka1 deletion rescue aberrant mitotic spindle formation induced by Mal3 overexpression in Schizosaccharomyces pombe. | Glucose limitation and pka1 deletion rescue aberrant mitotic spindle formation induced by Mal3 overexpression in Schizosaccharomyces pombe.
Tanabe T, Kawamukai M, Matsuo Y. | 02/13/2021 |
| findings suggest that Pka1 and the microtubule binding of the Mal3 CH domain play a role in the maintenance of proper chromosome segregation | Mal3 is a multi-copy suppressor of the sensitivity to microtubule-depolymerizing drugs and chromosome mis-segregation in a fission yeast pka1 mutant.
Tanabe T, Yamaga M, Kawamukai M, Matsuo Y., Free PMC Article | 01/4/2020 |
| PKA signalling tunes CLASP's activity to promote Pom1 cell side localization and buffer cell size upon glucose starvation. | PKA antagonizes CLASP-dependent microtubule stabilization to re-localize Pom1 and buffer cell size upon glucose limitation.
Kelkar M, Martin SG., Free PMC Article | 05/7/2016 |
| findings highlight the significance of glucose availability in regulation of TORC2-Gad8 and indicate a novel link between the cAMP/PKA, Pmk1/MAPK, and TORC2-Gad8 signaling | Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway.
Cohen A, Kupiec M, Weisman R., Free PMC Article | 12/20/2014 |
| Sty1 and PKA activity in stationary phase is essential for interaction between Sds23/Psp1/Moc1 and Ufd2. | Phosphorylations of Sds23/Psp1/Moc1 by stress-activated kinase and cAMP-dependent kinase are essential for regulating cell viability in prolonged stationary phase.
Jang YJ, Won M, Yoo HS. | 05/3/2014 |
| nuclear localization of Pka1 depends on its activity and hyperphosphorylation of Pka1 depends on Cgs1 interaction. | Multistep regulation of protein kinase A in its localization, phosphorylation and binding with a regulatory subunit in fission yeast.
Gupta DR, Paul SK, Oowatari Y, Matsuo Y, Kawamukai M. | 02/18/2012 |
| The double mutant tor2-51 pka1Delta showed a faster rate of accumulation of cells with 1C DNA content, indicating that the TOR and the PKA pathways cooperate to prevent cell cycle exit and G1 arrest in fission yeast. | TOR and PKA pathways synergize at the level of the Ste11 transcription factor to prevent mating and meiosis in fission yeast.
Valbuena N, Moreno S., Free PMC Article | 10/30/2010 |
| these results demonstrate the existence of a cAMP-independent mechanism of PKA catalytic subunit phosphorylation. | Phosphorylation of the protein kinase A catalytic subunit is induced by cyclic AMP deficiency and physiological stresses in the fission yeast, Schizosaccharomyces pombe.
McInnis B, Mitchell J, Marcus S., Free PMC Article | 10/23/2010 |
| Nuclear-cytoplasmic redistribution of Cgs1p and Pka1p is triggered by growth in glucose-limited or hyperosmotic media and in response to stationary-phase growth. | Regulation of the subcellular localization of cyclic AMP-dependent protein kinase in response to physiological stresses and sexual differentiation in the fission yeast Schizosaccharomyces pombe.
Matsuo Y, McInnis B, Marcus S., Free PMC Article | 01/21/2010 |
| From these results we propose that the effect of Ecl1 overproduction may be mainly linked to and negatively affects the Pka1-dependent pathway. | A novel gene, ecl1(+), extends the chronological lifespan in fission yeast.
Ohtsuka H, Mita S, Ogawa Y, Azuma K, Ito H, Aiba H. | 01/21/2010 |
| We found that strains carrying pka1 deletion but not those with sck2 deletion gained resistance to oxidative stress due to exposure to H(2)O(2) or menadione. | Regulation of chronological aging in Schizosaccharomyces pombe by the protein kinases Pka1 and Sck2.
Roux AE, Quissac A, Chartrand P, Ferbeyre G, Rokeach LA. | 01/21/2010 |