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    Icam1 intercellular adhesion molecule 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 25464, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis.

    Hypoxia-sensitive cells trigger NK cell activation via the KLF4-ASH1L-ICAM-1 axis, contributing to impairment in the rat epididymis.
    Zeng J, Gao W, Tang Y, Wang Y, Liu X, Yin J, Su X, Zhang M, Kang E, Tian Y, Ni B, He W.

    12/6/2023
    ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-kappaB in Pancreatic beta-Cells.

    ICAM-1 Abundance Is Increased in Pancreatic Islets of Hyperglycemic Female NOD Mice and Is Rapidly Upregulated by NF-κB in Pancreatic β-Cells.
    Martin TM, Burke SJ, Batdorf HM, Burk DH, Ghosh S, Dupuy SD, Karlstad MD, Collier JJ., Free PMC Article

    11/13/2023
    ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis.

    ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis.
    Yang P, Li F, Tang J, Tian Q, Zheng Z., Free PMC Article

    11/1/2023
    Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.

    Actin-binding protein, IQGAP1, regulates LPS-induced RPMVECs hyperpermeability and ICAM-1 upregulation via Rap1/Src signalling pathway.
    Zhang N, Wang G, Sun G.

    07/16/2022
    [Acupoint catgut embedment may reduce airway inflammation reaction by down-regulating ICAM-1 and EOS by suppressing p38MAPK signaling in lung tissue of asthmatic rats].

    [Acupoint catgut embedment may reduce airway inflammation reaction by down-regulating ICAM-1 and EOS by suppressing p38MAPK signaling in lung tissue of asthmatic rats].
    Tang XY, Chen PB, Du DJ, Qin ZY, Long RJ.

    03/5/2022
    Bioreducible, branched poly(beta-amino ester)s mediate anti-inflammatory ICAM-1 siRNA delivery against myocardial ischemia reperfusion (IR) injury.

    Bioreducible, branched poly(β-amino ester)s mediate anti-inflammatory ICAM-1 siRNA delivery against myocardial ischemia reperfusion (IR) injury.
    Wang X , Liang Q , Mao Y , Zhang R , Deng Q , Chen Y , Zhu R , Duan S , Yin L .

    06/26/2021
    Elevated expression of ICAM-1 in synovium is associated with early inflammatory response for cartilage degeneration in type 2 diabetes mellitus.

    Elevated expression of ICAM-1 in synovium is associated with early inflammatory response for cartilage degeneration in type 2 diabetes mellitus.
    Gui T, Lin YK, Huan SW, Li YH, Wang BH, Yang J, Gu RH, Liu Q, Li ZY, Li SM, Chen YF, Zhang HT, Zha ZG.

    09/5/2020
    The results found that capillaries and vascular smooth muscle cell content reduced, and nogo-B receptor and ICAM-1 were elevated in rats with diabetic erectile dysfunction.

    Silencing Nogo-B receptor inhibits penile corpus cavernosum vascular smooth muscle cell apoptosis of rats with diabetic erectile dysfunction by down-regulating ICAM-1.
    Zhang Y, Huo W, Wen Y, Li H., Free PMC Article

    03/28/2020
    lectin from Dioclea violacea significantly reduced carrageenan-induced leukocyte migration in the temporomandibular joint periarticular tissues mediated by down-regulation of ICAM-1 expression.

    Dioclea violacea lectin ameliorates inflammation in the temporomandibular joint of rats by suppressing intercellular adhesion molecule-1 expression.
    Clemente-Napimoga JT, Silva MASM, Peres SNC, Lopes AHP, Lossio CF, Oliveira MV, Osterne VJS, Nascimento KS, Abdalla HB, Teixeira JM, Cavada BS, Napimoga MH.

    03/2/2019
    MRTF-A overexpression synergistically enhanced the induction of FN and ICAM-1 by Advanced glycation end products.

    MRTF-A mediated FN and ICAM-1 expression in AGEs-induced rat glomerular mesangial cells via activating STAT5.
    Chen Q, Huang J, Gong W, Chen Z, Huang J, Liu P, Huang H.

    01/19/2019
    The results suggest that ICAM-1 may play a critical role in bladder inflammation in severe non-bacterial cystitis and may be used as a novel therapeutic target in non-bacterial bladder inflammation such as bladder pain syndrome/interstitial cystitis.

    Specific inhibition of ICAM-1 effectively reduces bladder inflammation in a rat model of severe non-bacterial cystitis.
    Zhang X, He H, Lu G, Xu T, Qin L, Wang X, Jin X, Liu B, Zhao Z, Shen Z, Shao Y., Free PMC Article

    04/21/2018
    Pro-atherogenic effects of aldosterone are mediated by increased ICAM-1 expression, through transcriptional regulation by endothelial MR.

    Essential role of ICAM-1 in aldosterone-induced atherosclerosis.
    Marzolla V, Armani A, Mammi C, Moss ME, Pagliarini V, Pontecorvo L, Antelmi A, Fabbri A, Rosano G, Jaffe IZ, Caprio M., Free PMC Article

    12/9/2017
    Berberine exhibited renoprotective effects in diabetic nephropathy (DN), and the underlying molecular mechanisms may be associated with changes in the levels and regulation of beta-arrestin 1/2 expression, as well as intercellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) levels in the kidney.

    Renoprotective effects of berberine and its potential effect on the expression of β-arrestins and intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in streptozocin-diabetic nephropathy rats.
    Tang LQ, Ni WJ, Cai M, Ding HH, Liu S, Zhang ST.

    04/22/2017
    Quercetin might protect against acute lung injury in rats with sepsis by suppressing ICAM-1 and MIP-2 expression.

    Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression.
    Meng L, Lv Z, Yu ZZ, Xu D, Yan X.

    03/4/2017
    MiR-146a regulates inflammatory macrophage infiltration in Polymyositis/Dermatomyositis by targeting TRAF6 and affecting the IL-17/ICAM-1 pathway.

    MiR-146a Regulates Inflammatory Infiltration by Macrophages in Polymyositis/Dermatomyositis by Targeting TRAF6 and Affecting IL-17/ICAM-1 Pathway.
    Yin Y, Li F, Shi J, Li S, Cai J, Jiang Y.

    02/18/2017
    The combination of DC vaccination and antiangionesis inhibited the rats with malignant glioma by stimulating immune response, supressing the expression of angiogenesis-related proteins VEGF, VCAM, and ICAM-1

    Dendritic cell vaccination enhances antiangiogenesis induced by endostatin in rat glioma.
    Zhou X, Liao Y, Li H, Zhao Z, Liu Q.

    12/24/2016
    The results of this study showed that ICAM-1 up regulation in both sexs rats with aneurysmal subarachnoid hemorrhage.

    Sexual dimorphism in gene expression after aneurysmal subarachnoid hemorrhage.
    Friedrich V, Bi W, Sehba FA., Free PMC Article

    11/5/2016
    intercellular adhesion molecule-1 has a role in the restructuring of the blood-testis barrier during spermatogenesis [review]

    Emergent roles for intercellular adhesion molecule-1 in the restructuring of the blood-testis barrier during spermatogenesis in the mammal.
    Mruk DD.

    10/22/2016
    ICAM-1 induction in vascular endothelium and leukocyte adhesion to vascular endothelium is decreased in NSun2 knock-out rats.

    NSun2 Deficiency Protects Endothelium From Inflammation via mRNA Methylation of ICAM-1.
    Luo Y, Feng J, Xu Q, Wang W, Wang X.

    07/30/2016
    ICAM-1 protein expression in the yellow wine (0.5% -1.5%) groups were significantly different. Yellow wine decreases ICAM-1 protein expression.

    Effects of Chinese yellow wine on nitric oxide synthase and intercellular adhesion molecule-1 expressions in rat vascular endothelial cells.
    Zhao F, Ji Z, Chi J, Tang W, Zhai X, Meng L, Guo H.

    04/30/2016
    Activation of Wnt/beta-catenin signaling in AECs attenuated intercellular adhesion molecule 1 (ICAM-1)/vascular cell adhesion molecule 1 (VCAM-1)-mediated adhesion of both macrophages and neutrophils to AECs.

    Platelet-derived Wnt antagonist Dickkopf-1 is implicated in ICAM-1/VCAM-1-mediated neutrophilic acute lung inflammation.
    Guo Y, Mishra A, Howland E, Zhao C, Shukla D, Weng T, Liu L., Free PMC Article

    02/13/2016
    PilE4:ICAM-1 interaction unfolded here may provide a new perspective on molecules involved in the adhesion of extracellular form of Francisella to endothelial cells.

    Deciphering the protein interaction in adhesion of Francisella tularensis subsp. holarctica to the endothelial cells.
    Bencurova E, Kovac A, Pulzova L, Gyuranecz M, Mlynarcik P, Mucha R, Vlachakis D, Kossida S, Flachbartova Z, Bhide M.

    12/19/2015
    findings reveal a novel function of ICAM-1 in osteogenesis and suggest a new molecular target to improve bone regeneration and repair in inflammatory microenvironments.

    Intercellular adhesion molecule-1 inhibits osteogenic differentiation of mesenchymal stem cells and impairs bio-scaffold-mediated bone regeneration in vivo.
    Xu FF, Zhu H, Li XM, Yang F, Chen JD, Tang B, Sun HG, Chu YN, Zheng RX, Liu YL, Wang LS, Zhang Y., Free PMC Article

    11/14/2015
    analysis of the role of Txnip, ICAM-1, and NOX2 expression in diabetes-induced endothelial dysfunctions with curcumin

    Molecular mechanisms of curcumin on diabetes-induced endothelial dysfunctions: Txnip, ICAM-1, and NOX2 expressions.
    Wongeakin N, Bhattarakosol P, Patumraj S., Free PMC Article

    10/10/2015
    No correlation was found between ICAM1 levels and microvascular or macrovascular dysfunction in adjuvant-induced arthritis.

    Microvascular abnormalities in adjuvant-induced arthritis: relationship to macrovascular endothelial function and markers of endothelial activation.
    Totoson P, Maguin-Gaté K, Nappey M, Prati C, Wendling D, Demougeot C.

    07/4/2015
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