| Study revealed age-related changes in tyrosine hydroxylase and DBH immunoreactivities in the carotid body glomus cells of spontaneously hypertensive (SHR/Izm) and Wistar Kyoto (WKY/Izm) rats at 4, 8, 12, and 16 weeks of age using immunohistochemistry. DBH age-dependently increased in the glomus cells of SHR/Izm in contrast to WKY/Izm. | Age-related changes in immunoreactivity for dopamine β-hydroxylase in carotid body glomus cells in spontaneously hypertensive rats.
Kato K, Fushuku S, Yamamoto Y. | 12/16/2017 |
| tyrosine hydroxylase and dopamine beta-hydroxylase-was evaluated in the organ of Zuckerkandl of rats in the critical period of morphogenesis | Gene expression and content of enzymes of noradrenaline synthesis in the rat organ of Zuckerkandl at the critical period of morphogenesis.
Murtazina AR, Nikishina YO, Bondarenko NS, Sapronova AY, Volina EV, Ugrumov MV. | 09/9/2017 |
| genetically determined decreases in adrenal expression and activity of DBH do not represent primary determinants of increased blood pressure in the SHR model | Effects of transgenic expression of dopamine beta hydroxylase (Dbh) gene on blood pressure in spontaneously hypertensive rats.
Pravenec M, Landa V, Zídek V, Mlejnek P, Šilhavý J, Mir SA, Vaingankar SM, Wang J, Kurtz TW., Free PMC Article | 04/1/2017 |
| With social isolation, no changes were observed in protein levels of DBH and NET in the right hippocampus, whereas expression of this norepinephrine synthetizing enzyme and transporter were elevated in the left hippocampus. | Hippocampal asymmetry in expression of catecholamine synthesizing enzyme and transporters in socially isolated rats.
Spasojevic N, Stanisavljevic D, Gavrilovic L, Jovanovic P, Cucakovic A, Dronjak S. | 03/9/2013 |
| Data suggest that the number of glomus cells with strong DBH immunoreactivity is increased in carotid bodies in spontaneously hypertensive rats compared with control rats; DBH is mainly observed in nerve fibers around blood vessels in control rats. | Increased total volume and dopamine β-hydroxylase immunoreactivity of carotid body in spontaneously hypertensive rats.
Kato K, Wakai J, Matsuda H, Kusakabe T, Yamamoto Y. | 09/29/2012 |
| Transcripts encoding catecholamine biosynthetic enzyme dopamine-beta-hydroxylase are unaffected by acute insulin treatment but are diminished by serial insulin dosing in hypoglycemic rats. | Quantitative RT-PCR and immunoblot analyses reveal acclimated A2 noradrenergic neuron substrate fuel transporter, glucokinase, phospho-AMPK, and dopamine-β-hydroxylase responses to hypoglycemia.
Cherian AK, Briski KP. | 03/31/2012 |
| Stress did not alter dopamine beta-hydroxylase expression in heart ventricles. | Regulation of catecholamine-synthesising enzymes and beta-adrenoceptors gene expression in ventricles of stressed rats.
Spasojevic N, Gavrilovic L, Dronjak S. | 02/11/2012 |
| The present study demonstrates an upregulatory effect of Phox2a and Phox2b on the expression of dopamine beta-hydroxylase and norepinephrine transporter in noradrenergic neurons of rat brains | Transcription factor Phox2 upregulates expression of norepinephrine transporter and dopamine β-hydroxylase in adult rat brains.
Fan Y, Huang J, Duffourc M, Kao RL, Ordway GA, Huang R, Zhu MY., Free PMC Article | 01/21/2012 |
| findings indicate two different mechanisms whereby DBH transcription is regulated by E(2) in the presence of ERalpha. | Varied mechanisms of oestradiol-mediated regulation of dopamine β-hydroxylase transcription.
Serova LI, Nostramo R, Veerasirikul M, Cappell DB, Sabban EL., Free PMC Article | 05/7/2011 |
| Psychosocial stress produced a significant increase of both TH mRNA and DBH mRNA levels in stellate ganglia. | Psychosocial stress-related changes in gene expression of norepinephrine biosynthetic enzymes in stellate ganglia of adult rats.
Gavrilovic L, Spasojevic N, Dronjak S. | 01/21/2010 |
| In chronically isolated rats, gene expression levels of dopamine-beta-hydroxylase in the adrenal medulla was decreased. | Chronic isolation of adult rats decreases gene expression of catecholamine biosynthetic enzymes in adrenal medulla.
Gavrilovic L, Spasojevic N, Tanic N, Dronjak S. | 01/21/2010 |
| Real-time quantitative polymerase-chain reaction was performed to quantify relative expression levels of mRNAs for catecholamine biosynthetic enzymes tyrosine hydroxylase, dopamine beta-hydroxylase and phenylethanolamine N-methyltransferase. | Expression levels of mRNAs for catecholamine biosynthetic enzymes as markers of acute response to contusion stress during the early postmortem period.
Takahashi S. | 01/21/2010 |
| The DBH mRNA in the locus coeruleus declined with increasing age to a 56% reduction in 23-month-old rats. | Age-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of rats.
Zhu MY, Wang WP, Iyo AH, Ordway GA, Kim KS., Free PMC Article | 01/21/2010 |
| detected for the first time the presence of DBH mRNA in micro dissected A5 cell group | Gene expression of catecholamine synthesizing enzymes in A5 cell group and modulation of tyrosine hydroxylase mRNA by immobilization stress.
Micutkova L, Kiss A, Filipenko M, Rychkova N, Krizanova O, Palkovits M, Kvetnansky R. | 01/21/2010 |
| dopamine-beta-hydroxylase gene expression is sensitive to glucoprivation in different catecholamine cell groups, demonstrating evidence of functional specialization within the total population | Differential responsiveness of dopamine-beta-hydroxylase gene expression to glucoprivation in different catecholamine cell groups.
Li AJ, Wang Q, Ritter S. | 01/21/2010 |
| High DBH activity in reinnervating sympathetic nerves after 3 days of culture may result from either accumulation in outgrowing nerve fibers of vesicles containing DBH or high activity in newly synthesized vesicles. | Dopamine-beta-hydroxylase activity during sympathetic reinnervation of rat iris in organ culture.
Johnson DG, Weise VK, Hanbauer I, Silberstein SD, Kopin IJ. | 01/21/2010 |
| findings are the first to reveal that estrogen can stimulate DBH gene expression | Estradiol stimulates gene expression of norepinephrine biosynthetic enzymes in rat locus coeruleus.
Serova L, Rivkin M, Nakashima A, Sabban EL. | 01/21/2010 |