SERPINE1 mRNA Binding Protein 1 Is Associated with Ischemic Stroke Risk: A Comprehensive Molecular-Genetic and Bioinformatics Analysis of SERBP1 SNPs. | SERPINE1 mRNA Binding Protein 1 Is Associated with Ischemic Stroke Risk: A Comprehensive Molecular-Genetic and Bioinformatics Analysis of SERBP1 SNPs. Shilenok I, Kobzeva K, Stetskaya T, Freidin M, Soldatova M, Deykin A, Soldatov V, Churnosov M, Polonikov A, Bushueva O., Free PMC Article | 08/23/2023 |
YY1-induced long non-coding RNA small nucleolar RNA host gene 8 promotes the tumorigenesis of melanoma via the microRNA-656-3p/SERPINE1 mRNA binding protein 1 axis. | YY1-induced long non-coding RNA small nucleolar RNA host gene 8 promotes the tumorigenesis of melanoma via the microRNA-656-3p/SERPINE1 mRNA binding protein 1 axis. Shan B, Qu S, Lv S, Fan D, Wang S., Free PMC Article | 04/16/2022 |
Circ_0046600 promotes hepatocellular carcinoma progression via up-regulating SERBP1 through sequestering miR-1258. | Circ_0046600 promotes hepatocellular carcinoma progression via up-regulating SERBP1 through sequestering miR-1258. Zhang D, Zhang Y, Zhang X, Zhai H, Sun X, Li Y. | 03/5/2022 |
G-Quadruplex-Induced Liquid-Liquid Phase Separation in Biomimetic Protocells. | G-Quadruplex-Induced Liquid-Liquid Phase Separation in Biomimetic Protocells. Liu X, Xiong Y, Zhang C, Lai R, Liu H, Peng R, Fu T, Liu Q, Fang X, Mann S, Tan W. | 02/5/2022 |
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCepsilon substrate influencing translation and cell division. | A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division. Martini S, Davis K, Faraway R, Elze L, Lockwood N, Jones A, Xie X, McDonald NQ, Mann DJ, Armstrong A, Ule J, Parker PJ., Free PMC Article | 01/8/2022 |
miR-362-3p acts as a tumor suppressor by targeting SERBP1 in ovarian cancer. | miR-362-3p acts as a tumor suppressor by targeting SERBP1 in ovarian cancer. Cao S, Li N, Liao X., Free PMC Article | 08/28/2021 |
CircRNA circBACH1 (hsa_circ_0061395) serves as a miR-656-3p sponge to facilitate hepatocellular carcinoma progression through increasing SERBP1 expression. | CircRNA circBACH1 (hsa_circ_0061395) serves as a miR-656-3p sponge to facilitate hepatocellular carcinoma progression through increasing SERBP1 expression. Li G, Du P, He J, Li Y. | 07/24/2021 |
The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. | The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation. Kosti A, de Araujo PR, Li WQ, Guardia GDA, Chiou J, Yi C, Ray D, Meliso F, Li YM, Delambre T, Qiao M, Burns SS, Lorbeer FK, Georgi F, Flosbach M, Klinnert S, Jenseit A, Lei X, Sandoval CR, Ha K, Zheng H, Pandey R, Gruslova A, Gupta YK, Brenner A, Kokovay E, Hughes TR, Morris QD, Galante PAF, Tiziani S, Penalva LOF., Free PMC Article | 07/10/2021 |
we revealed that PVT1 functions as an endogenous "sponge" by competing for miR-448 binding to regulate the miRNA target SERBP1 and, therefore, promotes the proliferation and migration of PC cells. | LncRNA-PVT1 promotes pancreatic cancer cells proliferation and migration through acting as a molecular sponge to regulate miR-448. Zhao L, Kong H, Sun H, Chen Z, Chen B, Zhou M. | 02/23/2019 |
All these results suggested that miR-218/SERBP1 signal pathway could inhibit the malignant phenotype formation and that targeting this pathway may be a potential novel way for HCC therapeutics. | MiR-218 suppresses the metastasis and EMT of HCC cells via targeting SERBP1. Wang T, Xu L, Jia R, Wei J. | 03/3/2018 |
Analysis of deletion constructs of SERBP1 showed that the C-terminal third of the SERBP1 protein, which contains one of its two substrate sites for protein arginine N-methyltransferase 1 (PRMT1), is necessary and sufficient for it to interact with RACK1 | The RNA-binding protein SERBP1 interacts selectively with the signaling protein RACK1. Bolger GB., Free PMC Article | 02/24/2018 |
Report a dynamic pattern of PGRMC1 and SERBP1 expression in human endometrium throughout the menstrual cycle and highlight a putative novel implication of PGRMC1 in the human decidualization process. | Dynamic expression of PGRMC1 and SERBP1 in human endometrium: an implication in the human decidualization process. Salsano S, Quiñonero A, Pérez S, Garrido Gómez T, Simón C, Dominguez F. | 11/18/2017 |
STMN1,COF1 and PAIRBP1 thus represent proteins associated with proliferative and aggressive tumors of high grades, while TSP2 and POSTN were connected to low grade tumors with better prognosis | Targeted proteomics driven verification of biomarker candidates associated with breast cancer aggressiveness. Procházková I, Lenčo J, Fučíková A, Dresler J, Čápková L, Hrstka R, Nenutil R, Bouchal P. | 07/22/2017 |
The effects of progesterone treatment on the expression levels of progesterone receptor membrane component 1 (PGRMC1), plasminogen activator inhibitor 1 RNA-binding protein (PAIRBP1), and progestin and adipoQ receptor 7 (PAQR7) on both mRNA and protein levels were investigated in spheroids derived from human glioma cell lines U-87 MG and LN-229. | Expression of Progesterone Receptor Membrane Component 1 (PGRMC1), Progestin and AdipoQ Receptor 7 (PAQPR7), and Plasminogen Activator Inhibitor 1 RNA-Binding Protein (PAIRBP1) in Glioma Spheroids In Vitro. Hlavaty J, Ertl R, Miller I, Gabriel C., Free PMC Article | 02/25/2017 |
Data indicate that serpine1 messenger RNA (mRNA) binding protein 1 (SERBP1) was identified as a downstream target of microRNA miR-26a-5p. | Loss of miR-26a-5p promotes proliferation, migration, and invasion in prostate cancer through negatively regulating SERBP1. Guo K, Zheng S, Xu Y, Xu A, Chen B, Wen Y. | 02/25/2017 |
SERBP1 is a component of the LRH-1 transcriptional complex. | SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex. Mari Y, West GM, Scharager-Tapia C, Pascal BD, Garcia-Ordonez RD, Griffin PR., Free PMC Article | 09/17/2016 |
PAI-RBP1 expression level is higher in non-small lung cancer tissues than in normal tissues. | Differential expression of PAI-RBP1, C1orf142, and COTL1 in non-small cell lung cancer cell lines with different tumor metastatic potential. Sun W, Guo C, Meng X, Yu Y, Jin Y, Tong D, Geng J, Huang Q, Qi J, Liu A, Guan R, Xu L, Sun D, Ji W, Liu P, Liu F, Sun H, Ji G, Fu S, Bai J. | 05/24/2014 |
Pseudomyogenic haemangioendothelioma consistently displays a SERPINE1-FOSB fusion gene, resulting from a translocation between chromosomes 7 and 19. | A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma. Walther C, Tayebwa J, Lilljebjörn H, Magnusson L, Nilsson J, von Steyern FV, Øra I, Domanski HA, Fioretos T, Nord KH, Fletcher CD, Mertens F. | 05/3/2014 |
The RNA-binding protein SERBP1 is abundantly expressed in human breast cancer and may represent a novel breast tumour marker with prognostic significance | Overexpression of SERBP1 (Plasminogen activator inhibitor 1 RNA binding protein) in human breast cancer is correlated with favourable prognosis. Serce NB, Boesl A, Klaman I, von Serényi S, Noetzel E, Press MF, Dimmler A, Hartmann A, Sehouli J, Knuechel R, Beckmann MW, Fasching PA, Dahl E., Free PMC Article | 07/27/2013 |
The RG-rich and RGG box of SERBP1 is asymmetrically dimethylated by PRMT1 and the modification affects protein interaction and intracellular localization of the protein. | Protein arginine methylation of SERBP1 by protein arginine methyltransferase 1 affects cytoplasmic/nuclear distribution. Lee YJ, Hsieh WY, Chen LY, Li C. | 10/20/2012 |
The aim of this study was to assess the expression, localization and hormonal regulation of two novel P(4) receptor candidates, P(4) receptor membrane component (PGRMC) 1 and PGRMC2, as well as the PGRMC1 partner Serpine 1 mRNA binding protein (SERBP1). | Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human. Zhang L, Kanda Y, Roberts DJ, Ecker JL, Losel R, Wehling M, Peluso JJ, Pru JK. | 01/21/2010 |
In ovarian cancer, PAI-RBP1 is significantly overexpressed in tumor epithelial cells, suggesting a biological role in tumor invasion and metastasis. Its expression is higher in advanced disease. | Expression analysis and RNA localization of PAI-RBP1 (SERBP1) in epithelial ovarian cancer: association with tumor progression. Koensgen D, Mustea A, Klaman I, Sun P, Zafrakas M, Lichtenegger W, Denkert C, Dahl E, Sehouli J. | 01/21/2010 |
The presence of the genotype risk factors alone does not seem to be associated with the development of preeclampsia even in the severe presentation form. PAI-1 gene polymorphisms on the development of the preeclampsia was indicated. | Relationship between polymorphisms in thrombophilic genes and preeclampsia in a Brazilian population. Dalmáz CA, Santos KG, Botton MR, Tedoldi CL, Roisenberg I. | 01/21/2010 |
interacts with the C-terminal region of the human chromatin-remodeling factor CHD-3 | Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3. Lemos TA, Passos DO, Nery FC, Kobarg J. | 01/21/2010 |
We observed that CGI-55 localizes to the nucleolus and co-localizes with p80-coilin positive nuclear-coiled bodies. | CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus. Lemos TA, Kobarg J. | 01/21/2010 |