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    GBP1 guanylate binding protein 1 [ Homo sapiens (human) ]

    Gene ID: 2633, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Guanylate-binding protein 1 inhibits Hantaan virus infection by restricting virus entry.

    Guanylate-binding protein 1 inhibits Hantaan virus infection by restricting virus entry.
    Gu T, Qu S, Zhang J, Ying Q, Zhang X, Lv Y, Liu R, Feng Y, Wang F, Wu X.

    07/11/2024
    GBP1 promotes cutaneous squamous cell carcinoma proliferation and invasion through activation of STAT3 by SP1.

    GBP1 promotes cutaneous squamous cell carcinoma proliferation and invasion through activation of STAT3 by SP1.
    Yu S, Li Y, Feng W, Zeng J, Cui X, Zhou S, Zhang P.

    06/13/2024
    Interferon-gamma-induced GBP1 is an inhibitor of human papillomavirus 18.

    Interferon-γ-induced GBP1 is an inhibitor of human papillomavirus 18.
    Xu M, Lin MC, Li ZH., Free PMC Article

    04/22/2024
    Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.

    Guanylate-binding protein 1 acts as a pro-viral factor for the life cycle of hepatitis C virus.
    Bender D, Koulouri A, Wen X, Glitscher M, Schollmeier A, Fernandes da Costa L, Murra RO, Carra GP, Haberger V, Praefcke GJK, Hildt E., Free PMC Article

    02/28/2024
    Function and mechanism of GBP1 in the development and progression of cervical cancer.

    Function and mechanism of GBP1 in the development and progression of cervical cancer.
    Wang S, Zhang Y, Ma X, Feng Y., Free PMC Article

    01/17/2024
    Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation.

    Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation.
    Bass AR, Egan MS, Alexander-Floyd J, Lopes Fischer N, Doerner J, Shin S., Free PMC Article

    01/3/2024
    BRCA1-associated RING domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA damage in Ewing sarcoma.

    BRCA1-associated RING domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA damage in Ewing sarcoma.
    Maurer LM, Daley JD, Mukherjee E, Venier RE, Julian CM, Bailey NG, Jacobs MF, Kumar-Sinha C, Raphael H, Periyapatna N, Weiss K, Janeway KA, Mody R, Lucas PC, McAllister-Lucas LM, Bailey KM., Free PMC Article

    07/27/2023
    Human GBP1 Is Involved in the Repair of Damaged Phagosomes/Endolysosomes.

    Human GBP1 Is Involved in the Repair of Damaged Phagosomes/Endolysosomes.
    Buijze H, Brinkmann V, Hurwitz R, Dorhoi A, Kaufmann SHE, Pei G., Free PMC Article

    06/15/2023
    Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.

    Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.
    Mariappan V, Adikari S, Shanmugam L, Easow JM, Balakrishna Pillai A.

    01/21/2023
    Guanylate Binding Protein 1 (GBP1): A Key Protein in Inflammatory Pyroptosis.

    Guanylate Binding Protein 1 (GBP1): A Key Protein in Inflammatory Pyroptosis.
    Johns CE, Galam L.

    07/23/2022
    Role of GBP1 in innate immunity and potential as a tuberculosis biomarker.

    Role of GBP1 in innate immunity and potential as a tuberculosis biomarker.
    Shi T, Huang L, Zhou Y, Tian J., Free PMC Article

    07/16/2022
    The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.

    The GBP1 microcapsule interferes with IcsA-dependent septin cage assembly around Shigella flexneri.
    Kutsch M, González-Prieto C, Lesser CF, Coers J., Free PMC Article

    01/29/2022
    Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation.

    Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation.
    Dilucca M, Ramos S, Shkarina K, Santos JC, Broz P., Free PMC Article

    12/25/2021
    Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels.

    Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels.
    Schuitemaker JHN, Beernink RHJ, Cremers TIFH, Scherjon SA, Van Pampus MG, Faas MM.

    12/11/2021
    Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis.

    Upregulation of GBP1 in thyroid primordium is required for developmental thyroid morphogenesis.
    Yang RM, Zhan M, Zhou QY, Ye XP, Wu FY, Dong M, Sun F, Fang Y, Zhang RJ, Zhang CR, Yang L, Guo MM, Zhang JX, Liang J, Cheng F, Liu W, Han B, Zhou Y, Zhao SX, Song HD., Free PMC Article

    10/30/2021
    Guanylate-binding protein 1 correlates with advanced tumor features, and serves as a prognostic biomarker for worse survival in lung adenocarcinoma patients.

    Guanylate-binding protein 1 correlates with advanced tumor features, and serves as a prognostic biomarker for worse survival in lung adenocarcinoma patients.
    Wan Q, Qu J, Li L, Gao F., Free PMC Article

    10/30/2021
    Structural requirements for membrane binding of human guanylate-binding protein 1.

    Structural requirements for membrane binding of human guanylate-binding protein 1.
    Sistemich L, Dimitrov Stanchev L, Kutsch M, Roux A, Günther Pomorski T, Herrmann C.

    08/7/2021
    Stimulation of GMP formation in hGBP1 is mediated by W79 and its effect on the antiviral activity.

    Stimulation of GMP formation in hGBP1 is mediated by W79 and its effect on the antiviral activity.
    Raninga N, Nayeem SM, Gupta S, Mullick R, Pandita E, Das S, Deep S, Sau AK.

    07/24/2021
    GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer.

    GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer.
    Meng Y, Wang W, Chen M, Chen K, Xia X, Zhou S, Yang H., Free PMC Article

    06/26/2021
    Catalytic activity of human guanylate-binding protein 1 coupled to the release of structural restraints imposed by the C-terminal domain.

    Catalytic activity of human guanylate-binding protein 1 coupled to the release of structural restraints imposed by the C-terminal domain.
    Ince S, Zhang P, Kutsch M, Krenczyk O, Shydlovskyi S, Herrmann C.

    06/19/2021
    GBP1 promotes erlotinib resistance via PGK1activated EMT signaling in nonsmall cell lung cancer.

    GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.
    Cheng L, Gou L, Wei T, Zhang J.

    06/12/2021
    Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death.

    Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death.
    Fisch D, Clough B, Domart MC, Encheva V, Bando H, Snijders AP, Collinson LM, Yamamoto M, Shenoy AR, Frickel EM., Free PMC Article

    05/29/2021
    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis.

    hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis.
    Xavier A, Al-Zeer MA, Meyer TF, Daumke O.

    05/22/2021
    Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.

    Direct binding of polymeric GBP1 to LPS disrupts bacterial cell envelope functions.
    Kutsch M, Sistemich L, Lesser CF, Goldberg MB, Herrmann C, Coers J., Free PMC Article

    04/13/2021
    Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.

    Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.
    Santos JC, Boucher D, Schneider LK, Demarco B, Dilucca M, Shkarina K, Heilig R, Chen KW, Lim RYH, Broz P., Free PMC Article

    09/5/2020
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