| Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs-NLRC4 association. | Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs-NLRC4 association.
Wen Z, Yuan T, Liu J, Wang D, Ni J, Yan X, Tang J, Tang J, Wu X, Wang Z. | 11/12/2024 |
| NLRC4-mediated pyroptosis was involved in coagulation disorders of acute pancreatitis. | NLRC4-mediated pyroptosis was involved in coagulation disorders of acute pancreatitis.
Hu S, Lin T, Chen Y, Guo Y, Sun X, Shi L, Pan J. | 04/8/2024 |
| Formylpeptide receptor 1 contributes to epidermal barrier dysfunction-induced skin inflammation through NOD-like receptor C4-dependent keratinocyte activation. | Formylpeptide receptor 1 contributes to epidermal barrier dysfunction-induced skin inflammation through NOD-like receptor C4-dependent keratinocyte activation.
Shao S, Sun Z, Chu M, Chen J, Cao T, Swindell WR, Bai Y, Li Q, Ma J, Zhu Z, Schuler A, Helfrich Y, Billi AC, Li Z, Hao J, Xiao C, Dang E, Gudjonsson JE, Wang G. | 03/18/2024 |
| Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis. | Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis.
An Y, Zhai Z, Wang X, Ding Y, He L, Li L, Mo Q, Mu C, Xie R, Liu T, Zhong W, Wang B, Cao H., Free PMC Article | 10/10/2023 |
| FlgM is required to evade NLRC4-mediated host protection against flagellated Salmonella. | FlgM is required to evade NLRC4-mediated host protection against flagellated Salmonella.
López-Yglesias AH, Lu CC, Lai MA, Quarles EK, Zhao X, Hajjar AM, Smith KD., Free PMC Article | 09/18/2023 |
| NLRC4 promotes the cGAS-STING signaling pathway by facilitating CBL-mediated K63-linked polyubiquitination of TBK1. | NLRC4 promotes the cGAS-STING signaling pathway by facilitating CBL-mediated K63-linked polyubiquitination of TBK1.
Zhang R, Yang W, Zhu H, Zhai J, Xue M, Zheng C. | 08/7/2023 |
| LNCGM1082-mediated NLRC4 activation drives resistance to bacterial infection. | LNCGM1082-mediated NLRC4 activation drives resistance to bacterial infection.
Gao Y, Yang Y, Wei J, Yue J, Wang Y, Zhang Q, Jin M, Wang R, Yang X, Zhang J, Liu X, Liu L, Zhang Y, Yang R., Free PMC Article | 05/25/2023 |
| Inflammasome activation and CCR2-mediated monocyte-derived dendritic cell recruitment restrict Legionella pneumophila infection. | Inflammasome activation and CCR2-mediated monocyte-derived dendritic cell recruitment restrict Legionella pneumophila infection.
Ataide MA, Manin GZ, Oliveira SS, Guerra RO, Zamboni DS. | 02/14/2023 |
| Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs-NLRC4 association. | Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs-NLRC4 association.
Chen X, Zhang Z, Sun N, Li J, Ma Z, Rao Z, Sun X, Zeng Q, Wu Y, Li J, Zhang J, Chen Y., Free PMC Article | 09/17/2022 |
| LCN2 Mediates Skin Inflammation in Psoriasis through the SREBP2NLRC4 Axis. | LCN2 Mediates Skin Inflammation in Psoriasis through the SREBP2‒NLRC4 Axis.
Ma J, Chen J, Xue K, Yu C, Dang E, Qiao H, Fang H, Pang B, Li Q, Sun Z, Qiao P, Wang L, Wang G, Shao S. | 07/30/2022 |
| Latent Upregulation of Nlrp3, Nlrc4 and Aim2 Differentiates between Asymptomatic and Symptomatic Trichomonas vaginalis Infection. | Latent Upregulation of Nlrp3, Nlrc4 and Aim2 Differentiates between Asymptomatic and Symptomatic Trichomonas vaginalis Infection.
Yadav S, Verma V, Dhanda RS, Khurana S, Yadav M. | 07/23/2022 |
| NLRC4 Deficiency Leads to Enhanced Phosphorylation of MLKL and Necroptosis. | NLRC4 Deficiency Leads to Enhanced Phosphorylation of MLKL and Necroptosis.
Sundaram B, Karki R, Kanneganti TD., Free PMC Article | 04/23/2022 |
| CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT. | CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT.
Mohamed MF, Gupta K, Goldufsky JW, Roy R, Callaghan LT, Wetzel DM, Kuzel TM, Reiser J, Shafikhani SH., Free PMC Article | 04/16/2022 |
| DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs. | DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Wang SB, Narendran S, Hirahara S, Varshney A, Pereira F, Apicella I, Ambati M, Ambati VL, Yerramothu P, Ambati K, Nagasaka Y, Argyle D, Huang P, Baker KL, Marion KM, Gupta K, Liu B, Hinton DR, Canna SW, Sallam T, Sadda SR, Kerur N, Gelfand BD, Ambati J., Free PMC Article | 03/12/2022 |
| Brd4 regulates NLRC4 inflammasome activation by facilitating IRF8-mediated transcription of Naips. | Brd4 regulates NLRC4 inflammasome activation by facilitating IRF8-mediated transcription of Naips.
Dong X, Hu X, Bao Y, Li G, Yang XD, Slauch JM, Chen LF., Free PMC Article | 09/11/2021 |
| Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption. | Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption.
Alippe Y, Kress D, Ricci B, Sun K, Yang T, Wang C, Xiao J, Abu-Amer Y, Mbalaviele G. | 08/28/2021 |
| Distinct Roles of IL-1beta and IL-18 in NLRC4-Induced Autoinflammation. | Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation.
Sasaki Y, Otsuka K, Arimochi H, Tsukumo SI, Yasutomo K., Free PMC Article | 06/26/2021 |
| Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling. | Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling.
Yang J, Hwang I, Lee E, Shin SJ, Lee EJ, Rhee JH, Yu JW., Free PMC Article | 06/19/2021 |
| Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression. | Intestinal epithelial NAIP/NLRC4 restricts systemic dissemination of the adapted pathogen Salmonella Typhimurium due to site-specific bacterial PAMP expression.
Hausmann A, Böck D, Geiser P, Berthold DL, Fattinger SA, Furter M, Bouman JA, Barthel-Scherrer M, Lang CM, Bakkeren E, Kolinko I, Diard M, Bumann D, Slack E, Regoes RR, Pilhofer M, Sellin ME, Hardt WD., Free PMC Article | 05/15/2021 |
| NLRC4 gene silencing-dependent blockade of NOD-like receptor pathway inhibits inflammation, reduces proliferation and increases apoptosis of dendritic cells in mice with septic shock. | NLRC4 gene silencing-dependent blockade of NOD-like receptor pathway inhibits inflammation, reduces proliferation and increases apoptosis of dendritic cells in mice with septic shock.
Wang SS, Yan CS, Luo JM., Free PMC Article | 05/8/2021 |
| Involvement of the NLRC4 inflammasome in promoting retinal ganglion cell death in an acute glaucoma mouse model. | Involvement of the NLRC4 inflammasome in promoting retinal ganglion cell death in an acute glaucoma mouse model.
Yao K, Zhao Y, Jin P, Lou X, Luo Z, Zhang H, Li F. | 04/24/2021 |
| NAIP-NLRC4-deficient mice are susceptible to shigellosis. | NAIP-NLRC4-deficient mice are susceptible to shigellosis.
Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE., Free PMC Article | 03/6/2021 |
| Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella. | Modifying bacterial flagellin to evade Nod-like Receptor CARD 4 recognition enhances protective immunity against Salmonella.
Tourlomousis P, Wright JA, Bittante AS, Hopkins LJ, Webster SJ, Bryant OJ, Mastroeni P, Maskell DJ, Bryant CE., Free PMC Article | 02/27/2021 |
| NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma. | NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.
Tenthorey JL, Chavez RA, Thompson TW, Deets KA, Vance RE, Rauch I., Free PMC Article | 02/20/2021 |
| Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages. | Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
Akhade AS, Atif SM, Lakshmi BS, Dikshit N, Hughes KT, Qadri A, Subramanian N., Free PMC Article | 01/23/2021 |