| Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway. | Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C., Free PMC Article | 07/29/2024 |
| Role and mechanism of Circ-PDE7B in the formation of keloid. | Role and mechanism of Circ-PDE7B in the formation of keloid.
Tang Y, Li X., Free PMC Article | 10/30/2023 |
| The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia. | The Prognostic Significance of PDE7B in Cytogenetically Normal Acute Myeloid Leukemia.
Cao L, Zhang W, Liu X, Yang P, Wang J, Hu K, Zhang X, Liu W, He X, Jing H, Yuan X., Free PMC Article | 11/21/2020 |
| We have identified three novel loci (PDE7B, UBL3, and a new independent marker in CDKN2B-AS1) associated with BRCAX, and replicated previously reported SNPs (24 of 92) and moderate/high-penetrance (seven of 23) genes for Korean BRCAX. For the novel candidate loci, evidence supported their roles in regulatory function | BRCA1/2-negative, high-risk breast cancers (BRCAX) for Asian women: genetic susceptibility loci and their potential impacts.
Lee JY, Kim J, Kim SW, Park SK, Ahn SH, Lee MH, Suh YJ, Noh DY, Son BH, Cho YU, Lee SB, Lee JW, Hopper JL, Sung J., Free PMC Article | 11/9/2019 |
| both low miR-200c and high PDE7B expression were correlated with poor survival of breast cancer patients. Our study supports a critical role of miR-200c/PDE7B relationship in triple-negative breast cancer tumorigenesis. | Phosphodiesterase 7B/microRNA-200c relationship regulates triple-negative breast cancer cell growth.
Zhang DD, Li Y, Xu Y, Kim J, Huang S., Free PMC Article | 03/2/2019 |
| PDE7B polymorphisms were not associated with schizophrenia risk. | PDE7B, NMBR and EPM2A Variants and Schizophrenia: A Case-Control and Pharmacogenetics Study.
Porcelli S, Balzarro B, Lee SJ, Han C, Patkar AA, Pae CU, Serretti A. | 02/18/2017 |
| higher expression of PDE7B might be a novel unfavorable prognostic indicator in MCL, which possess important clinical significance. | High expression of cyclic nucleotide phosphodiesterase 7B mRNA predicts poor prognosis in mantle cell lymphoma.
Fang C, Dong HJ, Zou ZJ, Fan L, Wang L, Zhang R, Xu J, Xu W, Li JY. | 06/8/2013 |
| PDE7B mRNA expression is obviously higher in mantle cell lymphoma patients compared with normal controls and significantly correlates with unfavorable cytogenetic characteristics. | [Expression of cyclic nucleotide phosphodiesterase 7B in patients with mantle cell lymphoma and its prognostic significance].
Dong HJ, Fan L, Wang DM, Fang C, Zhu DX, Wang YH, Hong M, Zhu Y, Qiao C, Zhuang Y, Xu W, Li JY. | 12/22/2012 |
| The low frequency of this 5' untranslated region variant indicates that it does not explain the higher PDE7B expression in patients with chronic lymphocytic leukemia (CLL) but it has the potential to influence other settings that involve a role for PDE7B. | Genetic variation in phosphodiesterase (PDE) 7B in chronic lymphocytic leukemia: overview of genetic variants of cyclic nucleotide PDEs in human disease.
Peiró AM, Tang CM, Murray F, Zhang L, Brown LM, Chou D, Rassenti L, Kipps TJ, Insel PA., Free PMC Article | 03/10/2012 |
| High PDE7B is associated with chronic lymphocytic leukemia. | Cyclic nucleotide phosphodiesterase 7B mRNA: an unfavorable characteristic in chronic lymphocytic leukemia.
Zhang L, Murray F, Rassenti LZ, Pu M, Kelly C, Kanter JR, Greaves A, Messer K, Kipps TJ, Insel PA., Free PMC Article | 10/1/2011 |
| Genetic variation in the phosphodiesterase 7B is associated with bioavailability of testosterone enanthate. | Bioavailability of testosterone enanthate dependent on genetic variation in the phosphodiesterase 7B but not on the uridine 5'-diphospho-glucuronosyltransferase (UGT2B17) gene.
Ekström L, Schulze JJ, Guillemette C, Belanger A, Rane A. | 08/20/2011 |
| As a first exploitation of this unique cohort, we identify three novel candidate dyslexia genes, ZNF280D and TCF12 at 15q21, and PDE7B at 6q23.3, by molecular mapping of the familial translocation with the 15q21 breakpoint. | A cohort of balanced reciprocal translocations associated with dyslexia: identification of two putative candidate genes at DYX1.
Buonincontri R, Bache I, Silahtaroglu A, Elbro C, Nielsen AM, Ullmann R, Arkesteijn G, Tommerup N. | 07/2/2011 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium., Free PMC Article | 09/15/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Human variation in alcohol response is influenced by variation in neuronal signaling genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL. | 04/7/2010 |
| Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.
Ikeda M, Tomita Y, Mouri A, Koga M, Okochi T, Yoshimura R, Yamanouchi Y, Kinoshita Y, Hashimoto R, Williams HJ, Takeda M, Nakamura J, Nabeshima T, Owen MJ, O'Donovan MC, Honda H, Arinami T, Ozaki N, Iwata N. | 12/2/2009 |
| higher levels than in normal B-cell of PDE7B are found in chronic lymphocytic leukemia | Cyclic nucleotide phosphodiesterase profiling reveals increased expression of phosphodiesterase 7B in chronic lymphocytic leukemia.
Zhang L, Murray F, Zahno A, Kanter JR, Chou D, Suda R, Fenlon M, Rassenti L, Cottam H, Kipps TJ, Insel PA., Free PMC Article | 01/21/2010 |