| Components of the insulin-like growth factor system in in vivo - and in vitro-derived fetuses of cattle, and the association with growth and development. | Components of the insulin-like growth factor system in in vivo - and in vitro-derived fetuses of cattle, and the association with growth and development.
Willhelm BR, Ticiani E, Campagnolo K, Rodrigues JL, Roberts AJ, Anderson GB, Bertolini M. | 01/29/2022 |
| Methylation pattern in a CpG island of the IGF2 gene in cumulus cells from 1-3 mm and >/= 8.0 mm follicles and the effects of in vitro maturation on this pattern. | Characterisation of the methylation pattern in the intragenic CpG island of the IGF2 gene in Bos taurus indicus cumulus cells during in vitro maturation.
Franco MM, Fagundes NS, Michalczechen-Lacerda VA, Caixeta ES, de Castro Rodrigues F, Machado GM, Ferreira AR, Dode MA., Free PMC Article | 10/11/2014 |
| Our results provide evidence that polymorphisms in the IGF2 gene are associated with growth traits, and may be used for marker-assisted selection in beef cattle breeding program | SNP and haplotype analysis reveal IGF2 variants associated with growth traits in Chinese Qinchuan cattle.
Huang YZ, Zhan ZY, Li XY, Wu SR, Sun YJ, Xue J, Lan XY, Lei CZ, Zhang CL, Jia YT, Chen H. | 10/4/2014 |
| The identification of the polymorphisms in the IGF2 gene that were significantly associated with growth traits in cattle. | Comparative analysis of the IGF2 and ZBED6 gene variants and haplotypes reveals significant effect of growth traits in cattle.
Huang YZ, Zhan ZY, Sun YJ, Wang J, Li MX, Lan XY, Lei CZ, Zhang CL, Chen H. | 04/5/2014 |
| Polymorphisms in the IGF2 gene are associated with cattle growth traits. | Assessment of association between variants and haplotypes of the IGF2 gene in beef cattle.
Huang YZ, Wang J, Zhan ZY, Cao XK, Sun YJ, Lan XY, Lei CZ, Zhang CL, Chen H. | 11/16/2013 |
| The LEP, IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls. | Allelic gene expression imbalance of bovine IGF2, LEP and CCL2 genes in liver, kidney and pituitary.
Olbromski R, Siadkowska E, Zelazowska B, Zwierzchowski L., Free PMC Article | 06/22/2013 |
| Sex-sorting procedure by flow cytometry did not affect the overall DNA methylation patterns of the IGF2 and IGF2R genes, although individual variation in their methylation patterns among bulls was observed. | The methylation patterns of the IGF2 and IGF2R genes in bovine spermatozoa are not affected by flow-cytometric sex sorting.
Carvalho JO, Michalczechen-Lacerda VA, Sartori R, Rodrigues FC, Bravim O, Franco MM, Dode MA. | 05/26/2012 |
| The reduction in IGFs mRNA level after 5 days of life in the duodenum (IGF-1 and IGF-2) and in the jejunum (IGF-1) was associated with reduction in villi length (duodenum and jejunum) and the increase of crypt depth (duodenum). | Insulin-like growth factors 1 and 2 (IGF-1 and IGF-2) mRNA levels in relation to the gastrointestinal tract (GIT) development in newborn calves.
Flaga J, Górka P, Kowalski ZM, Kaczor U, Pietrzak P, Zabielski R. | 05/12/2012 |
| Changes in the methylation pattern of IGF2 during in vitro maturation were different between incompetent and competent oocytes, and this characteristic may be useful as a molecular marker in studies of oocyte competence in cattle. | Methylation status in the intragenic differentially methylated region of the IGF2 locus in Bos taurus indicus oocytes with different developmental competencies.
Fagundes NS, Michalczechen-Lacerda VA, Caixeta ES, Machado GM, Rodrigues FC, Melo EO, Dode MA, Franco MM. | 05/7/2011 |
| Data describes the long-term changes to skeletal muscle growth and IGF1, 2, 1R, and 2R mRNA expression in progeny after exposure to high and low levels of maternal nutrient intake during the first two trimesters of gestation in the bovine. | Protein intake during gestation affects postnatal bovine skeletal muscle growth and relative expression of IGF1, IGF1R, IGF2 and IGF2R.
Micke GC, Sullivan TM, McMillen IC, Gentili S, Perry VE. | 04/30/2011 |
| findings support work which suggests that the insulin-like growth factor 2 locus is an important biological regulator of milk production in dairy cattle | Single nucleotide polymorphisms at the imprinted bovine insulin-like growth factor 2 (IGF2) locus are associated with dairy performance in Irish Holstein-Friesian cattle.
Berkowicz EW, Magee DA, Sikora KM, Berry DP, Howard DJ, Mullen MP, Evans RD, Spillane C, MacHugh DE. | 04/30/2011 |
| Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle. | Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle.
Curchoe CL, Zhang S, Yang L, Page R, Tian XC. | 01/21/2010 |
| study to assess the mRNA expression of IGF-I, IGF-II, IGF-IR and IGF-IIR in bovine oocytes and different stages of preimplantation embryos | Expression of IGF receptors and its ligands in bovine oocytes and preimplantation embryos.
Wang LM, Feng HL, Ma YZh, Cang M, Li HJ, Yan Zh, Zhou P, Wen JX, Bou S, Liu DJ. | 01/21/2010 |
| Among embryos developing in vivo, the level of DNA methylation in the IGF2 intragenic DMR was significantly lower in female than in male blastocysts | DNA methylation in the IGF2 intragenic DMR is re-established in a sex-specific manner in bovine blastocysts after somatic cloning.
Gebert C, Wrenzycki C, Herrmann D, Gröger D, Thiel J, Reinhardt R, Lehrach H, Hajkova P, Lucas-Hahn A, Carnwath JW, Niemann H. | 01/21/2010 |
| Dats detected that SNPs of IGF2 gene has close relationship with carcass and meat quality traits in Qinchuan cattle | [SNPs detection of IGF2 gene and its relationship with carcass and meat quality traits in Qinchuan cattle].
Han RH, Zan LS, Yang DP, Hao RC. | 01/21/2010 |
| The effect of single nucleotide polymorphisms in 6 genes and their associations with production factors in beef cattle are reported. | Polymorphisms and haplotypes in the bovine neuropeptide Y, growth hormone receptor, ghrelin, insulin-like growth factor 2, and uncoupling proteins 2 and 3 genes and their associations with measures of growth, performance, feed efficiency, and carcass merit in beef cattle.
Sherman EL, Nkrumah JD, Murdoch BM, Li C, Wang Z, Fu A, Moore SS. | 01/21/2010 |
| Embryonic tissues from NT-derived embryos had higher expression of IGF-II mRNA than in vitro production embryonic tissues. | Insulin-like growth factor (IGF) family genes are aberrantly expressed in bovine conceptuses produced in vitro or by nuclear transfer.
Moore K, Kramer JM, Rodriguez-Sallaberry CJ, Yelich JV, Drost M. | 01/21/2010 |
| The role of insulin-like growth factor 2 (IGF2) and the regulation of the IGF2 receptor (IGF2R) during follicular development were studied. | Insulin-like growth factor (IGF) 2 stimulates steroidogenesis and mitosis of bovine granulosa cells through the IGF1 receptor: role of follicle-stimulating hormone and IGF2 receptor.
Spicer LJ, Aad PY. | 01/21/2010 |
| Indel polymorphism associated with breeding value in bulls. | An InDel polymorphism in exon 6 of IGF2 associated with the breeding value of Polish Holstein-Friesian bulls.
Flisikowski K, Adamowicz T, Strabel T, Jankowski T, Switonski M, Zwierzchowski L. | 01/21/2010 |
| Identification of a previously unknown differentially methylated region in exon 10 of the bovine IGF2 gene. | The bovine IGF2 gene is differentially methylated in oocyte and sperm DNA.
Gebert C, Wrenzycki C, Herrmann D, Gröger D, Reinhardt R, Hajkova P, Lucas-Hahn A, Carnwath J, Lehrach H, Niemann H. | 01/21/2010 |
| effects of insulin, IGF-I and IGF-II on apoptosis and cell proliferation in bovine blastocysts in vitro | Regulation of apoptosis in the bovine blastocyst by insulin and the insulin-like growth factor (IGF) superfamily.
Byrne AT, Southgate J, Brison DR, Leese HJ. | 01/21/2010 |
| IGF2 is subjected to extensive transcriptional regulation through multiple promoters, alternative splicing and polyadenylation, as well as genetic imprinting.IGF2 regulation is age-, tissue-, promoter-, and allele-specific | Promoter-specific expression of the imprinted IGF2 gene in cattle (Bos taurus).
Curchoe C, Zhang S, Bin Y, Zhang X, Yang L, Feng D, O'Neill M, Tian XC. | 01/21/2010 |