| Endoplasmic reticulum distribution during bovine oocyte activation is regulated by protein kinase C via actin filaments. | Endoplasmic reticulum distribution during bovine oocyte activation is regulated by protein kinase C via actin filaments.
Feitosa WB, Lopes E, Visintin JA, Assumpção MEOD. | 03/13/2021 |
| The results of this study indicate the involvement of PKCalpha in the Ca (2+) signaling pathway in response to mechanical stress in endothelial cells. | Unloading of intercellular tension induces the directional translocation of PKCα.
Sera T, Arai M, Cui Z, Onose K, Karimi A, Kudo S. | 04/18/2020 |
| Mechanical stress induced biphasic and directional PKCalpha translocation | Spatial and temporal translocation of PKCα in single endothelial cell in response to mechanical stimulus.
Arai M, Sera T, Hasegawa T, Kudo S. | 03/9/2019 |
| AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production. | Protein kinase C and Src family kinases mediate angiotensin II-induced protein kinase D activation and acute aldosterone production.
Olala LO, Shapiro BA, Merchen TC, Wynn JJ, Bollag WB., Free PMC Article | 02/21/2015 |
| Significant changes in thin filament Ca2+-sensitivity, structure and kinetics are brought about through PKC phosphorylation of cardiac troponin T. | FRET study of the structural and kinetic effects of PKC phosphomimetic cardiac troponin T mutants on thin filament regulation.
Schlecht W, Zhou Z, Li KL, Rieck D, Ouyang Y, Dong WJ., Free PMC Article | 07/19/2014 |
| Data indicate the involvement of PKC-alpha in proMMP-2 activation and inhibition of TIMP-2 expression by NF-kappaB-MT1-MMP-dependent and -independent pathway. | Role of PKC-α in NF-κB-MT1-MMP-mediated activation of proMMP-2 by TNF-α in pulmonary artery smooth muscle cells.
Roy S, Chakraborti T, Chowdhury A, Chakraborti S. | 08/31/2013 |
| calcium-dependent phosphorylation of argininosuccinate synthase Ser-328 is mediated by PKCalpha | Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells.
Haines RJ, Corbin KD, Pendleton LC, Eichler DC., Free PMC Article | 10/13/2012 |
| VDAC phosphorylation is an important determinant of its interaction with dimeric tubulin. | Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin.
Sheldon KL, Maldonado EN, Lemasters JJ, Rostovtseva TK, Bezrukov SM., Free PMC Article | 02/18/2012 |
| Using yeast cells co-expressing the human wild-type p53 and a single mammalian PKCalpha, delta, epsilon or zeta, results showed a differential regulation of p53-mediated apoptosis by these PKC isoforms. | Distinct regulation of p53-mediated apoptosis by protein kinase Cα, δ, ε and ζ: Evidence in yeast for transcription-dependent and -independent p53 apoptotic mechanisms.
Coutinho I, Pereira C, Pereira G, Gonçalves J, Côrte-Real M, Saraiva L. | 06/4/2011 |
| degradation of protein kinase C(alpha)in sperm capacitation is mediated by PRKA | Protein kinase A and protein kinase C(alpha)/PPP1CC2 play opposing roles in the regulation of phosphatidylinositol 3-kinase activation in bovine sperm.
Rotman T, Etkovitz N, Spiegel A, Rubinstein S, Breitbart H. | 10/23/2010 |
| By regulating VEGFR2 expression and activation, PKC-epsilon expression is critical for activation of Akt and eNOS by VEGF and contributes to VEGF-stimulated Erk activation, whereas PKC-alpha has opposite effects. | Differential regulation of VEGF signaling by PKC-alpha and PKC-epsilon in endothelial cells.
Rask-Madsen C, King GL., Free PMC Article | 01/21/2010 |
| Protein kinase C mediated inhibition of endothelial L-arginine transport is mediated by MARCKS protein | Protein kinase C mediated inhibition of endothelial L-arginine transport is mediated by MARCKS protein.
Venardos K, Enriquez C, Marshall T, Chin-Dusting JP, Ahlers B, Kaye DM. | 01/21/2010 |
| analysis of amino acid critical for the catalytic competence and function of protein kinase Calpha | The last 10 amino acid residues beyond the hydrophobic motif are critical for the catalytic competence and function of protein kinase Calpha.
Yeong SS, Zhu Y, Smith D, Verma C, Lim WG, Tan BJ, Li QT, Cheung NS, Cai M, Zhu YZ, Zhou SF, Tan SL, Duan W. | 01/21/2010 |
| Data suggest that ceramide interacts with the calcium-dependent lipid binding C2 domain of protein kinase C alpha and thereby induces translocation of the enzyme to the Golgi compartment. | Ceramide induces translocation of protein kinase C-alpha to the Golgi compartment of human embryonic kidney cells by interacting with the C2 domain.
Aschrafi A, Franzen R, Shabahang S, Fabbro D, Pfeilschifter J, Huwiler A. | 01/21/2010 |