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    DROSHA drosha ribonuclease III [ Homo sapiens (human) ]

    Gene ID: 29102, updated on 27-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cytoplasmic and nuclear DROSHA in human villous trophoblasts.

    Cytoplasmic and nuclear DROSHA in human villous trophoblasts.
    Noguchi S, Ohkura S, Negishi Y, Tozawa S, Takizawa T, Morita R, Takahashi H, Ohkuchi A, Takizawa T.

    03/14/2024
    The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study.

    The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study.
    Kondkar AA, Azad TA, Sultan T, Osman EA, Almobarak FA, Lobo GP, Al-Obeidan SA., Free PMC Article

    05/1/2023
    Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells?

    Downregulation of DROSHA: Could It Affect miRNA Biogenesis in Endometriotic Menstrual Blood Mesenchymal Stem Cells?
    Cressoni ACL, Penariol LBC, Padovan CC, Orellana MD, Rosa-E-Silva JC, Poli-Neto OB, Ferriani RA, de Paz CCP, Meola J., Free PMC Article

    03/31/2023
    Association of DROSHA rs6877842, rs642321 and rs10719 polymorphisms with increased susceptibility to breast cancer: A case-control study with genotype and haplotype analysis.

    Association of DROSHA rs6877842, rs642321 and rs10719 polymorphisms with increased susceptibility to breast cancer: A case-control study with genotype and haplotype analysis.
    Kamalabad ST, Zamanzadeh Z, Rezaei H, Tabatabaeian M, Abkar M.

    03/14/2023
    Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis.

    Immunohistochemical expression of Drosha is reduced in eutopic and ectopic endometrium of women with adenomyosis.
    Ormenezi I, Ribeiro-Silva A, Rosa-E-Silva JC, Meola J, Candido-Dos-Reis FJ, Poli-Neto OB., Free PMC Article

    12/17/2022
    The Drosha-Independent MicroRNA6778-5p/GSK3beta Axis Mediates the Proliferation of Gastric Cancer Cells.

    The Drosha-Independent MicroRNA6778-5p/GSK3β Axis Mediates the Proliferation of Gastric Cancer Cells.
    Ren M, Xing L, Wang W, Bi W, Wu W, Jiang G, Wang W, Liang X, Liu M, Tang S., Free PMC Article

    10/15/2022
    The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder.

    The microRNA processor DROSHA is a candidate gene for a severe progressive neurological disorder.
    Barish S, Senturk M, Schoch K, Minogue AL, Lopergolo D, Fallerini C, Harland J, Seemann JH, Stong N, Kranz PG, Kansagra S, Mikati MA, Jasien J, El-Dairi M, Galluzzi P, Undiagnosed Diseases Network, Ariani F, Renieri A, Mari F, Wangler MF, Arur S, Jiang YH, Yamamoto S, Shashi V, Bellen HJ., Free PMC Article

    09/17/2022
    The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping.

    The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping.
    Duman G, Sariakcali B, Erşan S, Bakır S.

    04/16/2022
    p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.

    p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.
    Xu H, Liu X, Li W, Xi Y, Su P, Meng B, Shao X, Tang B, Yang Q, Mao Z., Free PMC Article

    02/19/2022
    Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.

    Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a.
    Fields CJ, Li L, Hiers NM, Li T, Sheng P, Huda T, Shan J, Gay L, Gu T, Bian J, Kilberg MS, Renne R, Xie M., Free PMC Article

    02/19/2022
    Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction.

    Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction.
    Bug DS, Tishkov AV, Moiseev IS, Petukhova NV., Free PMC Article

    01/1/2022
    Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster.

    Tissue-specific and transcription-dependent mechanisms regulate primary microRNA processing efficiency of the human chromosome 19 MicroRNA cluster.
    Fóthi Á, Biró O, Erdei Z, Apáti Á, Orbán TI., Free PMC Article

    01/1/2022
    Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.

    Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
    Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q., Free PMC Article

    01/1/2022
    Towards Understanding the Pathogenicity of DROSHA Mutations in Oncohematology.

    Towards Understanding the Pathogenicity of DROSHA Mutations in Oncohematology.
    Bug DS, Tishkov AV, Moiseev IS, Porozov YB, Petukhova NV., Free PMC Article

    11/22/2021
    Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells.

    Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells.
    Braun H, Hauke M, Ripperger A, Ihling C, Fuszard M, Eckenstaler R, Benndorf RA., Free PMC Article

    10/23/2021
    High Glucose Treatment Limits Drosha Protein Expression and Alters AngiomiR Maturation in Microvascular Primary Endothelial Cells via an Mdm2-dependent Mechanism.

    High Glucose Treatment Limits Drosha Protein Expression and Alters AngiomiR Maturation in Microvascular Primary Endothelial Cells via an Mdm2-dependent Mechanism.
    Lam B, Nwadozi E, Haas TL, Birot O, Roudier E., Free PMC Article

    10/23/2021
    Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.

    Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.
    Fawzy MS, Abu AlSel BT, Toraih EA., Free PMC Article

    10/23/2021
    Molecular determinants that govern scaRNA processing by Drosha/DGCR8.

    Molecular determinants that govern scaRNA processing by Drosha/DGCR8.
    McLaurin DM, Logan MK, Lett KE, Hebert MD., Free PMC Article

    10/16/2021
    Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.

    Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.
    Dai L, Hallmark L, Bofill De Ros X, Crouch H, Chen S, Shi T, Yang A, Lian C, Zhao Y, Tran B, Gu S., Free PMC Article

    09/18/2021
    A quantitative map of human primary microRNA processing sites.

    A quantitative map of human primary microRNA processing sites.
    Kim K, Baek SC, Lee YY, Bastiaanssen C, Kim J, Kim H, Kim VN.

    09/4/2021
    Dicer and Drosha expression in patients with nephrotic syndrome.

    Dicer and Drosha expression in patients with nephrotic syndrome.
    Hejazian SM, Rahbar Saadat Y, Bahmanpour Z, Hosseiniyan Khatibi SM, Ardalan M, Zununi Vahed S.

    08/28/2021
    Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8.

    Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8.
    de Kock L, Rivera B, Foulkes WD.

    06/12/2021
    Evaluation of the clinical significance of RNase III enzyme DROSHA in pediatrics acute lymphocytic leukemia.

    Evaluation of the clinical significance of RNase III enzyme DROSHA in pediatrics acute lymphocytic leukemia.
    Hajirostamlou M, Ghorbian S.

    05/22/2021
    DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.

    DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.
    Cardoso JV, Medeiros R, Dias F, Costa IA, Ferrari R, Berardo PT, Perini JA.

    04/24/2021
    Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma.

    Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma.
    Mohammadpour-Gharehbagh A, Heidari Z, Eskandari M, Aryan A, Salimi S.

    03/27/2021
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