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    Dcn decorin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29139, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction.

    The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction.
    Hassan GM, Ebrahim RH.

    06/13/2023
    Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury.

    Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury.
    Gáspár R, Gömöri K, Kiss B, Szántai Á, Pálóczi J, Varga ZV, Pipis J, Váradi B, Ágg B, Csont T, Ferdinandy P, Barteková M, Görbe A., Free PMC Article

    03/6/2021
    overexpression of decorin ameliorated diabetic cardiomyopathy and promoted angiogenesis through the IGF1R-AKT-VEGF signaling pathway in vivo and in vitro.

    Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling.
    Lai J, Chen F, Chen J, Ruan G, He M, Chen C, Tang J, Wang DW., Free PMC Article

    11/10/2018
    The spatio-temporal expression of Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi in developing prostate is described and observed similar mesenchymal expression patterns in rat and human.

    Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
    Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA., Free PMC Article

    01/12/2013
    Data show that the overexpression of OTUB1 enhanced the ubiquitination and degradation of Decorin (DCN)in mesangial cells (MC).

    OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level.
    Zhang Y, Hu R, Wu H, Jiang W, Sun Y, Wang Y, Song Y, Jin T, Zhang H, Mao X, Zhao Z, Zhang Z., Free PMC Article

    07/14/2012
    Regulating the ubiquitination and degradation of DCN might be a novel approach for modulating mesangial cell bioactivity.

    Regulation of intracellular decorin via proteasome degradation in rat mesangial cells.
    Wu H, Jiang W, Zhang Y, Liu Y, Zhao Z, Guo M, Ma D, Zhang Z.

    02/12/2011
    analysis of the high-resolution model of the decoron-fibril collagen complex

    Decorin core protein (decoron) shape complements collagen fibril surface structure and mediates its binding.
    Orgel JP, Eid A, Antipova O, Bella J, Scott JE., Free PMC Article

    02/8/2010
    Decorin expression was significantly decreased on rat vocal fold postinjury days 1, 3, 7, and 56.

    Extracellular matrix gene expression during wound healing of the injured rat vocal fold.
    Ohno T, Hirano S, Rousseau B.

    01/21/2010
    Overexpression of decorin could inhibit mesangial cell proliferation by inducing apoptosis and cell growth arrest in vitro and it also downregulates expression of TGF-beta1.

    Overexpression of decorin induces apoptosis and cell growth arrest in cultured rat mesangial cells in vitro.
    Wu H, Wang S, Xue A, Liu Y, Liu Y, Wang H, Chen Q, Guo M, Zhang Z.

    01/21/2010
    These results suggest that decorin participates in the quiescence of myogenic cells.

    Decorin expression in quiescent myogenic cells.
    Nishimura T, Nozu K, Kishioka Y, Wakamatsu J, Hattori A.

    01/21/2010
    Overexpression of decorin down-regulates the expression of TGFbeta1 and extracellular matrix components from rat mesangial cells.

    Decorin gene transfer inhibited the expression of TGFbeta1 and ECM in rat mesangial cells.
    Wu F, Yao H, Bader A, Dong F, Zhu F, Wu N, Wang B, Li H, Brockmeyer NH, Altmeyer P.

    01/21/2010
    Decorin mRNA abundance in fetal skeletal muscle was significantly higher than those in neonates and adults.

    Spatiotemporal expression of decorin and myostatin during rat skeletal muscle development.
    Nishimura T, Oyama K, Kishioka Y, Wakamatsu J, Hattori A.

    01/21/2010
    a novel collagen binding domain in decorin acts cooperatively with leucine-rich repeat 4 to mask the alpha2beta1 integrin-binding site on collagen, an important sequence for the phagocytosis of collagen fibrils

    Collagen phagocytosis by fibroblasts is regulated by decorin.
    Bhide VM, Laschinger CA, Arora PD, Lee W, Hakkinen L, Larjava H, Sodek J, McCulloch CA.

    01/21/2010
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