The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction. | The myokine decorin improves the cardiac function in a rat model of isoprenaline-induced myocardial infarction. Hassan GM, Ebrahim RH. | 06/13/2023 |
Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury. | Decorin Protects Cardiac Myocytes against Simulated Ischemia/Reperfusion Injury. Gáspár R, Gömöri K, Kiss B, Szántai Á, Pálóczi J, Varga ZV, Pipis J, Váradi B, Ágg B, Csont T, Ferdinandy P, Barteková M, Görbe A., Free PMC Article | 03/6/2021 |
overexpression of decorin ameliorated diabetic cardiomyopathy and promoted angiogenesis through the IGF1R-AKT-VEGF signaling pathway in vivo and in vitro. | Overexpression of decorin promoted angiogenesis in diabetic cardiomyopathy via IGF1R-AKT-VEGF signaling. Lai J, Chen F, Chen J, Ruan G, He M, Chen C, Tang J, Wang DW., Free PMC Article | 11/10/2018 |
The spatio-temporal expression of Decorin, Semaphorin6D, SPARC, Spry-1 and Tsukushi in developing prostate is described and observed similar mesenchymal expression patterns in rat and human. | Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer. Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA., Free PMC Article | 01/12/2013 |
Data show that the overexpression of OTUB1 enhanced the ubiquitination and degradation of Decorin (DCN)in mesangial cells (MC). | OTUB1 overexpression in mesangial cells is a novel regulator in the pathogenesis of glomerulonephritis through the decrease of DCN level. Zhang Y, Hu R, Wu H, Jiang W, Sun Y, Wang Y, Song Y, Jin T, Zhang H, Mao X, Zhao Z, Zhang Z., Free PMC Article | 07/14/2012 |
Regulating the ubiquitination and degradation of DCN might be a novel approach for modulating mesangial cell bioactivity. | Regulation of intracellular decorin via proteasome degradation in rat mesangial cells. Wu H, Jiang W, Zhang Y, Liu Y, Zhao Z, Guo M, Ma D, Zhang Z. | 02/12/2011 |
analysis of the high-resolution model of the decoron-fibril collagen complex | Decorin core protein (decoron) shape complements collagen fibril surface structure and mediates its binding. Orgel JP, Eid A, Antipova O, Bella J, Scott JE., Free PMC Article | 02/8/2010 |
Decorin expression was significantly decreased on rat vocal fold postinjury days 1, 3, 7, and 56. | Extracellular matrix gene expression during wound healing of the injured rat vocal fold. Ohno T, Hirano S, Rousseau B. | 01/21/2010 |
Overexpression of decorin could inhibit mesangial cell proliferation by inducing apoptosis and cell growth arrest in vitro and it also downregulates expression of TGF-beta1. | Overexpression of decorin induces apoptosis and cell growth arrest in cultured rat mesangial cells in vitro. Wu H, Wang S, Xue A, Liu Y, Liu Y, Wang H, Chen Q, Guo M, Zhang Z. | 01/21/2010 |
These results suggest that decorin participates in the quiescence of myogenic cells. | Decorin expression in quiescent myogenic cells. Nishimura T, Nozu K, Kishioka Y, Wakamatsu J, Hattori A. | 01/21/2010 |
Overexpression of decorin down-regulates the expression of TGFbeta1 and extracellular matrix components from rat mesangial cells. | Decorin gene transfer inhibited the expression of TGFbeta1 and ECM in rat mesangial cells. Wu F, Yao H, Bader A, Dong F, Zhu F, Wu N, Wang B, Li H, Brockmeyer NH, Altmeyer P. | 01/21/2010 |
Decorin mRNA abundance in fetal skeletal muscle was significantly higher than those in neonates and adults. | Spatiotemporal expression of decorin and myostatin during rat skeletal muscle development. Nishimura T, Oyama K, Kishioka Y, Wakamatsu J, Hattori A. | 01/21/2010 |
a novel collagen binding domain in decorin acts cooperatively with leucine-rich repeat 4 to mask the alpha2beta1 integrin-binding site on collagen, an important sequence for the phagocytosis of collagen fibrils | Collagen phagocytosis by fibroblasts is regulated by decorin. Bhide VM, Laschinger CA, Arora PD, Lee W, Hakkinen L, Larjava H, Sodek J, McCulloch CA. | 01/21/2010 |