Hirschsprung's disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3beta. | Hirschsprung's disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3β. Yang Y, Zhang M, Li N, Wang C, Yang H, Hou X, Yang J, Fan K, Yang L, Wu K. | 10/25/2024 |
Regulation of Glycogen Synthase Kinase-3beta by Phosphorylation and O-beta-Linked N-Acetylglucosaminylation: Implications on Tau Protein Phosphorylation. | Regulation of Glycogen Synthase Kinase-3β by Phosphorylation and O-β-Linked N-Acetylglucosaminylation: Implications on Tau Protein Phosphorylation. El Hajjar L, Page A, Bridot C, Cantrelle FX, Landrieu I, Smet-Nocca C. | 10/21/2024 |
Anti-inflammatory effects of MerTK by inducing M2 macrophage polarization via PI3K/Akt/GSK-3beta pathway in gout. | Anti-inflammatory effects of MerTK by inducing M2 macrophage polarization via PI3K/Akt/GSK-3β pathway in gout. Chen F, Li Y, Zhao L, Lin C, Zhou Y, Ye W, Wan W, Zou H, Xue Y. | 10/17/2024 |
Synergistic Effect between the APOE epsilon4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease. | Synergistic Effect between the APOE ε4 Allele with Genetic Variants of GSK3B and MAPT: Differential Profile between Refractory Epilepsy and Alzheimer Disease. Toral-Rios D, Pichardo-Rojas P, Ruiz-Sánchez E, Rosas-Carrasco Ó, Carvajal-García R, Gálvez-Coutiño DC, Martínez-Rodríguez NL, Rubio-Chávez AD, Alcántara-Flores M, López-Ramírez A, Martínez-Rosas AR, Ruiz-Chow ÁA, Alonso-Vanegas M, Campos-Peña V., Free PMC Article | 10/3/2024 |
Structural and functional effects of phosphopriming and scaffolding in the kinase GSK-3beta. | Structural and functional effects of phosphopriming and scaffolding in the kinase GSK-3β. Enos MD, Gavagan M, Jameson N, Zalatan JG, Weis WI., | 09/13/2024 |
GSK3: A potential target and pending issues for treatment of Alzheimer's disease. | GSK3: A potential target and pending issues for treatment of Alzheimer's disease. Zhao J, Wei M, Guo M, Wang M, Niu H, Xu T, Zhou Y., Free PMC Article | 07/11/2024 |
GSK3beta and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer. | GSK3β and UCHL3 govern RIPK4 homeostasis via deubiquitination to enhance tumor metastasis in ovarian cancer. Shan W, Peng W, Chen Y, Wang Y, Yu Q, Tian Y, Dou Y, Tu J, Huang X, Li X, Wang Z, Zhu Q, Chen J, Xia B. | 06/28/2024 |
MiR-29a efficiently suppresses the generation of reactive oxygen species and alpha-synuclein in a cellular model of Parkinson's disease by potentially targeting GSK-3beta. | MiR-29a efficiently suppresses the generation of reactive oxygen species and α-synuclein in a cellular model of Parkinson's disease by potentially targeting GSK-3β. Yang YL, Lin TK, Huang YH. | 05/30/2024 |
Association of glycogen synthase kinase-3beta with cognitive impairment in type 2 diabetes patients: a six-year follow-up study. | Association of glycogen synthase kinase-3β with cognitive impairment in type 2 diabetes patients: a six-year follow-up study. Wei W, Xu P, Li L, Mao H, Li N, Wang XQ, Wang L, Xu ZP, Zhao S., Free PMC Article | 05/8/2024 |
NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3beta. | NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β. McCurry CM, Sunilkumar S, Subrahmanian SM, Yerlikaya EI, Toro AL, VanCleave AM, Stevens SA, Barber AJ, Sundstrom JM, Dennis MD., Free PMC Article | 04/2/2024 |
Glutamine transporter SLC38A3 promotes breast cancer metastasis via Gsk3beta/beta-catenin/EMT pathway. | Glutamine transporter SLC38A3 promotes breast cancer metastasis via Gsk3β/β-catenin/EMT pathway. Tan Z, Boyapati K, Tressler CM, Jenkinson NM, Glunde K. | 03/19/2024 |
GSK3beta: A ray of hope for the treatment of diabetic kidney disease. | GSK3β: A ray of hope for the treatment of diabetic kidney disease. Liang LL, He MF, Zhou PP, Pan SK, Liu DW, Liu ZS. | 03/8/2024 |
Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3beta-mediated glucose uptake. | Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake. Lu W, Chen Z, Xu H, Shen Z, Wu Z, Li M. | 02/16/2024 |
27-Hydroxycholesterol activates the GSK-3beta/beta-catenin signaling pathway resulting in intestinal fibrosis by inducing oxidative stress: effect of dietary interventions. | 27-Hydroxycholesterol activates the GSK-3β/β-catenin signaling pathway resulting in intestinal fibrosis by inducing oxidative stress: effect of dietary interventions. Xiao W, Hu C, Ni Y, Wang J, Jiao K, Zhou M, Li Z. | 02/16/2024 |
Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3beta at Thr252 by in Vitro Studies. | Determining Structural Changes for Ligand Recognition between Human and Rat Phosphorylated BACE1 in Silico and Its Phosphorylation by GSK3β at Thr252 by in Vitro Studies. Velazquez Toledano J, Bello M, Correa Basurto J, Guerrero González I, Pacheco-Yépez J, Rosales Hernández MC. | 02/13/2024 |
GSK-3beta as a Potential Coordinator of Anabolic and Catabolic Pathways in Hepatitis C Virus Insulin Resistance. | GSK-3β as a Potential Coordinator of Anabolic and Catabolic Pathways in Hepatitis C Virus Insulin Resistance. Das GC, Hollinger FB., Free PMC Article | 02/13/2024 |
GSK-3beta activation mediates apolipoprotein E4-associated cognitive impairment in type 2 diabetes mellitus: A multicenter, cross-sectional study. | GSK-3β activation mediates apolipoprotein E4-associated cognitive impairment in type 2 diabetes mellitus: A multicenter, cross-sectional study. Gao Y, Yu H, Liu Y, Xu Z, He B, Liu H, Wang Y, Zhang Y, Liang Y, Yang Y, Zheng J, Wang JZ., Free PMC Article | 02/7/2024 |
Intrarenal and Urinary Glycogen Synthase Kinase-3 Beta Levels in Diabetic and Nondiabetic Chronic Kidney Disease. | Intrarenal and Urinary Glycogen Synthase Kinase-3 Beta Levels in Diabetic and Nondiabetic Chronic Kidney Disease. Zeng L, Ng JK, Fung WW, Chan GC, Chow KM, Szeto CC., Free PMC Article | 01/11/2024 |
NRF1 knockdown alleviates lipopolysaccharide-induced pulmonary inflammatory injury by upregulating DKK3 and inhibiting the GSK-3beta/beta-catenin pathway. | NRF1 knockdown alleviates lipopolysaccharide-induced pulmonary inflammatory injury by upregulating DKK3 and inhibiting the GSK-3β/β-catenin pathway. Kang L, Wang X, Wang J, Guo J, Zhang W, Lei R., Free PMC Article | 12/20/2023 |
Phosphorylation of USP27X by GSK3beta maintains the stability and oncogenic functions of CBX2. | Phosphorylation of USP27X by GSK3β maintains the stability and oncogenic functions of CBX2. Xing Y, Ba-Tu J, Dong C, Cao X, Li B, Jia X, Juan Y, Lv X, Zhang H, Qin N, Han W, Wang D, Qi X, Wang Y, Hao X, Zhang S, Du X, Wang H, Wang M., Free PMC Article | 12/4/2023 |
Modulation of PI3K/Akt/GSK3beta signaling cascade through G protein-coupled receptor 55 (GPR55) activation: Prenatal lysophosphatidylinositol attenuates valproic acid-induced synaptic abnormalities and mitochondrial dysfunction. | Modulation of PI3K/Akt/GSK3β signaling cascade through G protein-coupled receptor 55 (GPR55) activation: Prenatal lysophosphatidylinositol attenuates valproic acid-induced synaptic abnormalities and mitochondrial dysfunction. Ahmed S, Abir AH, Sharmin O, Khurshid N, Akter A, Nakshy NT, Hasan MM, Yesmine S, Rahman M. | 11/29/2023 |
Transcriptional Regulation of the Human 5-HT1A Receptor Gene by Lithium: Role of Deaf1 and GSK3beta. | Transcriptional Regulation of the Human 5-HT1A Receptor Gene by Lithium: Role of Deaf1 and GSK3β. Harkin EF, Nasrallah G, Le François B, Albert PR., Free PMC Article | 11/29/2023 |
Interferon-gamma inducible protein 30 promotes the epithelial-mesenchymal transition-like phenotype and chemoresistance by activating EGFR/AKT/GSK3beta/beta-catenin pathway in glioma. | Interferon-γ inducible protein 30 promotes the epithelial-mesenchymal transition-like phenotype and chemoresistance by activating EGFR/AKT/GSK3β/β-catenin pathway in glioma. Chen Y, Xu H, Yu P, Wang Q, Li S, Ji F, Wu C, Lan Q., Free PMC Article | 11/28/2023 |
FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3beta/GLI1 pathway. | FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway. Yin L, Cao R, Liu Z, Luo G, Li Y, Zhou X, Chen X, Wu Y, He J, Zu X, Shen Y., Free PMC Article | 11/22/2023 |
Suspension state affects the stemness of breast cancer cells by regulating the glycogen synthase kinase-3beta. | Suspension state affects the stemness of breast cancer cells by regulating the glycogen synthase kinase-3β. Chen L, Lv Y. | 11/16/2023 |