| HSP90beta regulates EAAT2 expression and participates in ischemia-reperfusion injury in rats. | HSP90β regulates EAAT2 expression and participates in ischemia‑reperfusion injury in rats.
Liang T, Hu X, Zeng L, Zhou Z, Zhang J, Xu Z, Zeng J, Xu P., Free PMC Article | 11/30/2023 |
| Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats. | Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats.
Cheng S, Xu J, Wang W, Wang R, Li H, Jiang Z, Liu D, Pan F. | 10/28/2023 |
| Bone marrow stromal cells-derived exosomes reduce neurological damage in traumatic brain injury through the miR-124-3p/p38 MAPK/GLT-1 axis. | Bone marrow stromal cells-derived exosomes reduce neurological damage in traumatic brain injury through the miR-124-3p/p38 MAPK/GLT-1 axis.
Zhuang Z, Liu M, Dai Z, Luo J, Zhang B, Yu H, Xue J, Xu H. | 05/22/2023 |
| LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p. | LncRNA BIRF Promotes Brain Ischemic Tolerance Induced By Cerebral Ischemic Preconditioning Through Upregulating GLT-1 via Sponging miR-330-5p.
Li S, Zhang L, Lin J, Su A, Liu X, Zhang J, Xian X, Hu Y, Li W, Sun S, Zhang M., Free PMC Article | 06/18/2022 |
| Induction of Parkinsonian-Like Changes via Targeted Downregulation of Astrocytic Glutamate Transporter GLT-1 in the Striatum. | Induction of Parkinsonian-Like Changes via Targeted Downregulation of Astrocytic Glutamate Transporter GLT-1 in the Striatum.
Ren C, He KJ, Hu H, Zhang JB, Dong LG, Li D, Chen J, Mao CJ, Wang F, Liu CF. | 05/7/2022 |
| Downregulation of astroglial glutamate transporter GLT-1 in the lateral habenula is associated with depressive-like behaviors in a rat model of Parkinson's disease. | Downregulation of astroglial glutamate transporter GLT-1 in the lateral habenula is associated with depressive-like behaviors in a rat model of Parkinson's disease.
Lyu S, Guo Y, Zhang L, Tang G, Li R, Yang J, Gao S, Li W, Liu J. | 02/5/2022 |
| Glutamate transporter 1-expressing glia in the rat substantia nigra-Morphometric analysis and relationships to synapses. | Glutamate transporter 1-expressing glia in the rat substantia nigra-Morphometric analysis and relationships to synapses.
Kessler JP, Salin P, Kerkerian-Le Goff L. | 11/13/2021 |
| Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2. | Midazolam contributes to neuroprotection against hypoxia/reoxygenation-induced brain injury in neonatal rats via regulation of EAAT2.
Tang Z, Yang F, Dong Y, Ma C, Sun S, Shan Y, Zhang Y, Liu H. | 10/2/2021 |
| RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats. | RAGE Signaling pathway in hippocampus dentate gyrus involved in GLT-1 decrease induced by chronic unpredictable stress in rats.
Yang F, Wang H, Chen H, Ran D, Tang Q, Weng P, Sun Y, Jiang W. | 10/2/2021 |
| Rapid recycling of glutamate transporters on the astroglial surface. | Rapid recycling of glutamate transporters on the astroglial surface.
Michaluk P, Heller JP, Rusakov DA., Free PMC Article | 09/18/2021 |
| Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression. | Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression.
Martinez-Lozada Z, Robinson MB., Free PMC Article | 08/14/2021 |
| The role of glutamate transporter-1 in firing activity of locus coeruleus neurons and nociception in rats. | The role of glutamate transporter-1 in firing activity of locus coeruleus neurons and nociception in rats.
Nozad A, Hamidi N, Amani M. | 08/7/2021 |
| Dysregulation of EAAT2 and VGLUT2 Spinal Glutamate Transports via Histone Deacetylase 2 (HDAC2) Contributes to Paclitaxel-induced Painful Neuropathy. | Dysregulation of EAAT2 and VGLUT2 Spinal Glutamate Transports via Histone Deacetylase 2 (HDAC2) Contributes to Paclitaxel-induced Painful Neuropathy.
Wang XM, Gu P, Saligan L, Iadarola M, Wong SSC, Ti LK, Cheung CW. | 08/7/2021 |
| Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine. | Up-regulation of astrocyte excitatory amino acid transporter 2 alleviates central sensitization in a rat model of chronic migraine.
Zhou X, Liang J, Wang J, Fei Z, Qin G, Zhang D, Zhou J, Chen L. | 03/13/2021 |
| Amyloid Fibril-Induced Astrocytic Glutamate Transporter Disruption Contributes to Complement C1q-Mediated Microglial Pruning of Glutamatergic Synapses. | Amyloid Fibril-Induced Astrocytic Glutamate Transporter Disruption Contributes to Complement C1q-Mediated Microglial Pruning of Glutamatergic Synapses.
Wu J, Bie B, Foss JF, Naguib M. | 02/6/2021 |
| Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model. | Ceftriaxone Treatment Preserves Cortical Inhibitory Interneuron Function via Transient Salvage of GLT-1 in a Rat Traumatic Brain Injury Model.
Hameed MQ, Hsieh TH, Morales-Quezada L, Lee HHC, Damar U, MacMullin PC, Hensch TK, Rotenberg A., Free PMC Article | 10/24/2020 |
| Study on ceramide modulates EAAT-2 participation in the immunoinflammatory response in schizophrenia. | Study on ceramide modulates EAAT-2 participation in the immunoinflammatory response in schizophrenia.
Ling WM, Chen MC, Zhang YC, Ou MM, Gu LZ. | 08/15/2020 |
| Results indicated that miR-124 could regulate GLT-1 expression in astrocytes after OGD/reperfusion through the Akt and mTOR pathway. | miR-124 upregulates astrocytic glutamate transporter-1 via the Akt and mTOR signaling pathway post ischemic stroke.
Huang WY, Jiang C, Ye HB, Jiao JT, Cheng C, Huang J, Liu J, Zhang R, Shao JF. | 07/25/2020 |
| Down-expressed GLT-1 in PSD astrocytes stimulated NSCs differentiating into astrocytes, but inhibiting the formation of functional synapses by influencing glutamate metabolism in vitro. | Down-expressed GLT-1 in PSD astrocytes inhibits synaptic formation of NSC-derived neurons in vitro.
Yu D, Cheng Z, Ali AI, Wang J, Le K, Chibaatar E, Guo Y., Free PMC Article | 02/22/2020 |
| The study suggested that low hippocampal content of SLC1A2 is a potential biomarker of epilepsy and may affect the function of neurons through the glutamatergic synapse pathway. | SLC1A2 mediates refractory temporal lobe epilepsy with an initial precipitating injury by targeting the glutamatergic synapse pathway.
Zhang Y, Dong H, Duan L, Yuan G, Liang W, Li Q, Zhang X, Pan Y. | 01/18/2020 |
| Study shows that chronic unexpected mild stress destroys synaptic plasticity of regenerated neurons in the hippocampus through a glutamate transporter, GLT-1, of astrocytes in the ischemic stroke rats. | Chronic Unexpected Mild Stress Destroys Synaptic Plasticity of Neurons through a Glutamate Transporter, GLT-1, of Astrocytes in the Ischemic Stroke Rat.
Yu D, Cheng Z, Ali AI, Wang J, Le K, Chibaatar E, Guo Y., Free PMC Article | 12/14/2019 |
| GLT1 is reduced around the somata of orexin neurons while increased around melanin-concentrating hormone neurons following sleep deprivation | Sleep Deprivation Distinctly Alters Glutamate Transporter 1 Apposition and Excitatory Transmission to Orexin and MCH Neurons.
Briggs C, Hirasawa M, Semba K., Free PMC Article | 07/13/2019 |
| The results of this study suggested that the initial increased GLT1 activity depends on injury input and serves to dampen the development of hyperalgesia. | Altered glial glutamate transporter expression in descending circuitry and the emergence of pain chronicity.
Guo W, Imai S, Zou S, Yang J, Watanabe M, Wang J, Dubner R, Wei F, Ren K., Free PMC Article | 05/18/2019 |
| Expression of glutamate transporter-1 (GLT-1) in the supplementary motor area is reduced after strenuous exercise, resulting in an increased extracellular glutamate concentration and decreased extracellular lactate level that may be responsible for the development of fatigue. GLT-1-mediated uptake of glutamate ameliorates exercise-induced fatigue in rat models. | GLT-1 mediates exercise-induced fatigue through modulation of glutamate and lactate in rats.
Wang D, Wang X. | 10/20/2018 |
| Chronic voluntary wheel running results in increased gene expression of GLT-1 (and VGLUT3) in the frontal cortex without changes in other glutamate transporter subtypes. | Increased gene expression of selected vesicular and glial glutamate transporters in the frontal cortex in rats exposed to voluntary wheel running.
Graban J, Hlavacova N, Jezova D. | 08/18/2018 |