| Gluk1 and NETO1 specifically promote dendrite growth of interneurons in the visual cortex. | Development of Cortical Pyramidal Cell and Interneuronal Dendrites: a Role for Kainate Receptor Subunits and NETO1.
Jack A, Hamad MIK, Gonda S, Gralla S, Pahl S, Hollmann M, Wahle P. | 01/18/2020 |
| Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain. | Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain.
Duan GF, Ye Y, Xu S, Tao W, Zhao S, Jin T, Nicoll RA, Shi YS, Sheng N., Free PMC Article | 12/22/2018 |
| In the CA1 hippocampal pyramidal cell, GluK1 had no effect on synaptic transmission. GluK1 which requires the auxiliary subunits Neto1 and Neto2 for surface and synaptic trafficking. It is the amino-terminal domains of GluK1 and GluK2 that control their strikingly different trafficking properties. | Amino-terminal domains of kainate receptors determine the differential dependence on Neto auxiliary subunits for trafficking.
Sheng N, Shi YS, Nicoll RA., Free PMC Article | 04/28/2018 |
| Functional GluK1 (kainic acid)-containing receptors are present postsynaptically on vasopressin neurons but not on oxytocin cells. | Kainate receptor-induced retrograde inhibition of glutamatergic transmission in vasopressin neurons.
Bonfardin VD, Theodosis DT, Konnerth A, Oliet SH., Free PMC Article | 03/17/2012 |
| ATPA up-regulated mRNA and protein levels of GluR5, but coriaria lactone down-regulated GluR5 and GluR6 in astrocytes. | [Different expression of GluR5 and GluR6 in rat astrocyte induced with coriaria lactone and ATPA].
Peng F, Li JM, Li Q, Yao ZP, Zhou D. | 10/1/2011 |
| study demonstrates there is a tonic effect on inhibitory synaptic transmission in hippocampal CA1 pyramidal cells regulated by endogenous glutamate via GluR5 kainate receptor which is age dependent | Age-dependent enhancement of inhibitory synaptic transmission in CA1 pyramidal neurons via GluR5 kainate receptors.
Xu C, Cui C, Alkon DL. | 01/21/2010 |
| Kainate receptors containing the GLU(K5) subunit are critically important for generation and frequency oscillation in the entorhinal cortex. | The role of GLU K5-containing kainate receptors in entorhinal cortex gamma frequency oscillations.
Stanger HL, Alford R, Jane DE, Cunningham MO., Free PMC Article | 01/21/2010 |
| Therefore, GLU(K5) kainate receptor subunits are involved in kindling-induced plasticity changes in the amygdala. | Activation of kainate GLU(K5) transmission rescues kindling-induced impairment of LTP in the rat lateral amygdala.
Schubert M, Albrecht D. | 01/21/2010 |
| analysis of how GluR5-containing kainate receptor activation has a role in neuroprotection against ischemic brain injury through decreasing tyrosine phosphorylation of N-methyl-D-aspartate receptors mediated by Src kinase | Neuroprotection of GluR5-containing kainate receptor activation against ischemic brain injury through decreasing tyrosine phosphorylation of N-methyl-D-aspartate receptors mediated by Src kinase.
Xu J, Liu Y, Zhang GY., Free PMC Article | 01/21/2010 |
| GluR5 subunit-containing kainate-type glutamate receptors have a role in the formation and/or stabilization of functional glutamatergic synapses in area CA1. | Activation of kainate receptors controls the number of functional glutamatergic synapses in the area CA1 of rat hippocampus.
Vesikansa A, Sallert M, Taira T, Lauri SE., Free PMC Article | 01/21/2010 |
| Hippocampal mossy-fiber long-term potentiation is independent of GLUR5. | Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
Breustedt J, Schmitz D., Free PMC Article | 01/21/2010 |
| Selective upregulation of kainate receptor subunit KA1 expression contributes to inflammatory hyperalgesia. | Activation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression.
Guo W, Zou S, Tal M, Ren K. | 01/21/2010 |
| High-resolution crystal structures of the GluR5 ligand-binding core complex with antagonists UBP302 & UBP310 show they bind by a new mechanism involving a 22-angstrom core extension. | Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists.
Mayer ML, Ghosal A, Dolman NP, Jane DE., Free PMC Article | 01/21/2010 |