| Regulation of Synapse Weakening through Interactions of the Microtubule Associated Protein Tau with PACSIN1. | Regulation of Synapse Weakening through Interactions of the Microtubule Associated Protein Tau with PACSIN1.
Regan P, Mitchell SJ, Kim SC, Lee Y, Yi JH, Barbati SA, Shaw C, Cho K., Free PMC Article | 12/4/2021 |
| PACSIN1 is a versatile membrane deformation protein that links the endocytic and recycling machineries essential for dynamic AMPA receptor trafficking in neurons. | PACSIN1 regulates the dynamics of AMPA receptor trafficking.
Widagdo J, Fang H, Jang SE, Anggono V., Free PMC Article | 04/28/2018 |
| The SdpI-binding site was mapped to a proline-rich sequence of 22 amino acids within the intracellular loop of GlyRbeta. | Proteomic analysis of glycine receptor β subunit (GlyRβ)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors.
Del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I., Free PMC Article | 06/7/2014 |
| PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression. | PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.
Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY, Linden DJ, Plomann M, Huganir RL., Free PMC Article | 11/30/2013 |
| Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation | Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation.
Quan A, Xue J, Wielens J, Smillie KJ, Anggono V, Parker MW, Cousin MA, Graham ME, Robinson PJ., Free PMC Article | 05/5/2012 |
| Syndapin I was identified as the first non-kinase substrate for CaMKK. | Identification of a novel CaMKK substrate.
Fujimoto T, Hatano N, Nozaki N, Yurimoto S, Kobayashi R, Tokumitsu H. | 09/3/2011 |
| syndapin 1 and novel protein kinase Cepsilon (nPKCepsilon) were identified as the TP-associated proteins | Biochemical characterization of tau protein and its associated syndapin 1 and protein kinase Cepsilon for their functional regulation in rat brain.
Suzuki K, Kawakami F, Sasaki H, Maruyama H, Ohtsuki K. | 01/21/2010 |
| We propose syndapin and endophilin function either at different stages during SVE or in mechanistically distinct types of SVE. | Syndapin I and endophilin I bind overlapping proline-rich regions of dynamin I: role in synaptic vesicle endocytosis.
Anggono V, Robinson PJ. | 01/21/2010 |
| in addition to a crucial role in endocytic internalization, syndapin protein complexes play an important role in endocytic receptor recycling | EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling.
Braun A, Pinyol R, Dahlhaus R, Koch D, Fonarev P, Grant BD, Kessels MM, Qualmann B., Free PMC Article | 01/21/2010 |
| Syndapin has been identified as a binding partner for both neural cell adhesion molecule (NCAM)-140 and NCAM-180 isoforms in rat brain cytosol. | Novel cytosolic binding partners of the neural cell adhesion molecule: mapping the binding domains of PLC gamma, LANP, TOAD-64, syndapin, PP1, and PP2A.
Büttner B, Kannicht C, Reutter W, Horstkorte R. | 01/21/2010 |
| SPIN90-PRD, a syndapin-binding domain, significantly inhibited endocytosis, and the inhibition was reversed by co-expression of syndapin. | Interaction of SPIN90 with syndapin is implicated in clathrin-mediated endocytic pathway in fibroblasts.
Kim SH, Choi HJ, Lee KW, Hong NH, Sung BH, Choi KY, Kim SM, Chang S, Eom SH, Song WK. | 01/21/2010 |
| Syndapins may coordinate N-WASP and dynamin functions during receptor-mediated endocytosis. Local actin polymerization induced by syndapin-N-WASP interactions may support clathrin-coated vesicle detachment and movement away from the plasma membrane. | Syndapins integrate N-WASP in receptor-mediated endocytosis.
Kessels MM, Qualmann B., Free PMC Article | 01/21/2010 |
| Syndapin oligomers may act as multivalent organizers spatially and temporally coordinating vesicle fission with local actin polymerization. | Syndapin oligomers interconnect the machineries for endocytic vesicle formation and actin polymerization.
Kessels MM, Qualmann B. | 01/21/2010 |
| Thus syndapin I is a central component of the endocytic protein complex for SVE via stimulus-dependent recruitment to dynamin I and has a key role in synaptic transmission. | Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis.
Anggono V, Smillie KJ, Graham ME, Valova VA, Cousin MA, Robinson PJ., Free PMC Article | 01/21/2010 |